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Researchers discover novel therapy for Crohn's disease
Date:3/19/2012

fessor of Immunology at NIMML.

NIMML strives to develop safer and more effective therapies for human chronic inflammatory diseases from Nature's own medicine cabinet. To achieve this, NIMML uses advanced computational modeling in addition to mechanistic and clinical experimentation. "The validation of the anti-inflammatory actions of CLA in the gut is in line with our goal because CLA is a natural fatty acid found in milk and ruminant products. The fully integrated bioinformatics, nutrition and immunology experimentation capabilities of NIMML enable the acceleration of translational biomedical research from computational and mathematical modeling into the clinic. CLA is an example of an anti-inflammatory compound in a pipeline of naturally occurring and synthetic compounds (e.g., abscisic acid, eleostearic acid, terephthalanilides) with tremendous therapeutic and prophylactic potential as anti-inflammatories," said Dr. Josep Bassaganya-Riera, a Professor of Immunology, principal investigator of this human clinical trial, and the Director of the NIMML and the Center for Modeling Immunity to Enteric Pathogens.

These findings, reported in the most recent edition of Clinical Nutrition1, were awarded the American College of Gastroenterology Presidential Poster of distinction for human clinical trials.


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Contact: Tiffany Trent
ttrebt@vbi.vt.edu
540-231-6822
Virginia Tech
Source:Eurekalert  

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