Navigation Links
Researchers discover novel anti-viral immune pathway in the mosquito
Date:1/10/2012

As mosquito-borne viral diseases like West Nile fever, dengue fever, and chikungunya fever spread rapidly around the globe, scientists at Virginia Tech are working to understand the mosquito's immune system and how the viral pathogens that cause these diseases are able to overcome it to be transmitted to human and animal hosts.

In nearly every part of the world, humans and animals experience high levels of morbidity and mortality after being bitten by mosquitoes infected with viruses. More than 100 different viruses transmitted by blood feeding arthropods like mosquitoes have been associated with human or animal disease.

Two especially prolific vectors are the yellow fever mosquito (Aedes aegypti) and Asian tiger mosquito (Aedes albopictus), which is easy to spot because of its striped patterning. Although native to Africa and Asia, these insects can spread through the western world by hitching rides in used tires, which trap water to create a perfect breeding site.

Virginia Tech researchers have identified a novel anti-viral pathway in the immune system of culicine mosquitoes, the insect family to which both vectors belong. Kevin Myles and Zach Adelman, both associate professors of entomology in the College of Agriculture and Life Sciences, lead the research, which is published in the Jan . 5 PLoS Pathogens article, "Production of Virus-Derived Ping-Pong-Dependent piRNA-like Small RNAs in the Mosquito Soma," by Elaine M. Morazzani and Michael R. Wiley, Ph.D. students in entomology; Marta G. Murreddu, research associate in entomology; and Adelman; and Myles.

"We have previously shown that an antiviral response directed by small interfering RNAs (siRNAs) is present in culicine mosquito vectors. However, we show here that another class of virus-derived small RNAS, exhibiting many similarities with ping-pong-dependent piwi-interacting RNAs (piRNAs) is also produced in the soma of culicine mosquitoes,"
'/>"/>

Contact: Lindsay Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert  

Page: 1 2

Related biology news :

1. MU researchers find unique protein organization in arteries associated with cardiovascular disease
2. Frogs use calls to find mates with matching chromosomes, University of Missouri researchers find
3. Viagra against heart failure: Researchers at the RUB and from Rochester throw light on the mechanism
4. DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels
5. Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers
6. Researchers develop new method of cleaning toxins from the oilsands
7. Researchers discover a way to significantly reduce the production costs of fuel cells
8. San Diego Zoo researchers contribute to project using mummy DNA to differentiate croc species
9. Researchers create living neon signs composed of millions of glowing bacteria
10. Georgetown researchers lead discovery expected to significantly change biomedical research
11. 4 UC Riverside researchers receive national recognition
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover novel anti-viral immune pathway in the mosquito
(Date:7/29/2014)... July 29, 2014 Research and Markets ... Business Intelligence (BI) Market 2014-2018" report to their ... The term BI refers to applications and ... or analyzing information about a company,s operations. BI help ... their business; for example, metrics on sales, production, and ...
(Date:7/29/2014)... of a stroke is an immensely complex challenge ... as effective therapy. Advancing such knowledge to improve ... focus of research by Sergei Adamovich, associate professor ... faculty more than a decade ago. It is ... from sources such as the National Institutes of ...
(Date:7/29/2014)... YORK , July 29, 2014  When it comes to ... new devices, if not the last. However, when it comes to ... Though the market for the Internet of Things and its ... make an impact in the healthcare industry, whether it,s in the ... to keep us fit. With that in mind, InformationWeek ...
Breaking Biology News(10 mins):Global SaaS-based Business Intelligence (BI) Market 2014-2018 2Continuing the quest for better stroke therapies 2Continuing the quest for better stroke therapies 3
... 2013Dr. Carissa Klein of Australia was awarded the APEC ... by John Wiley & Sons, Inc., and Elsevier, on ... Research and Technology. Dr. Klein,s selection is ... Queensland that uniquely addresses the issue of sustainable ocean ...
... The strain of cholera that has sickened thousands in Haiti ... to the island over the past three years as some ... mBio , the online open-access journal of the American Society ... are consistent with earlier findings that indicate Vibrio cholerae ...
... TEMPE, Ariz -- Knowing virtually everything about how the ... for instance, precisely how particular cells develop into ... in understanding the basics of what drives biological processes. ... advances in medical science, bioengineering and related areas. ...
Cached Biology News:ASPIRE prize winner balances ocean conservation and socioeconomic viability 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 3Biomedical research revealing secrets of cell behavior 2
(Date:7/29/2014)... , July 29, 2014  Discovery Laboratories, Inc. ... advancing a new standard of respiratory critical care, will ... August 5, 2014 before the open of the ... will host a live teleconference and webcast at ... conference call, Discovery Labs, management will discuss the ...
(Date:7/29/2014)... , July 29, 2014  ImmunoClin Corporation (IMCL) ... medicine, treatment of infectious diseases as well as ... and prevention of pathologies like cardiovascular disease, Alzheimer,s ... 2014, ImmunoClin Corporation will complete the strategic relocation ... D.C. , a key center of North ...
(Date:7/29/2014)... 2014 Genera Energy Inc. ... innovation and supply chain advancements, has announced the ... Energy Grange™ and Supply ASSURE™. Both systems ... testing aimed at consolidating and simplifying the entire ... farmers and feedstock end users. , “Through the ...
(Date:7/29/2014)... July 29, 2014  United Therapeutics Corporation (NASDAQ: ... financial results for the second quarter ended ... shows that our medicines are reaching increasing ... hypertension (PAH)," said Martine Rothblatt, Ph.D., United ... commercial launch this quarter of our extended-release ...
Breaking Biology Technology:Discovery Labs to Report 2014 Second Quarter Financial Results and Hold Conference Call on Tuesday, August 5, 2014 at 9:00 a.m. Eastern Time 2ImmunoClin Corporation (IMCL) Relocates Corporate Headquarters to Washington, DC 2ImmunoClin Corporation (IMCL) Relocates Corporate Headquarters to Washington, DC 3Genera Energy Introduces Proprietary Feedstock Management Systems 2Genera Energy Introduces Proprietary Feedstock Management Systems 3Genera Energy Introduces Proprietary Feedstock Management Systems 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 2United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 5United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 6United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 7United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 8United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 9United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 10United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 11United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 12United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 13
...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... Neurocrine Biosciences, will be presenting at the 24th Annual Roth ... takes place on Tuesday, March 13 at 2:00 p.m. Pacific ... webcast and may be accessed on the Company,s website at ...
... ATLANTA, March 7, 2012 Harriet L. Robinson, Ph.D., ... a biotech company specializing in the development of HIV/AIDS ... scientists may be one step closer to a vaccine ... study results were unveiled by Dr. Robinson during a ...
... BETHESDA, Md., March 7, 2012   Spherix Incorporated ... innovator in biotechnology for therapy in diabetes, metabolic ... regulatory consulting services to food, supplement, biotechnology and ... its drug candidates, SPX-106T, arrested development and reduced ...
Cached Biology Technology:GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 2GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 3GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 4SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 2SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 3SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 4
Mouse monoclonal [4i144] to HLA Class II DQ1 7 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 2 Antigen DQ1,7....
ASCIZ...
Goat polyclonal to CHMP5 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-NKDGVLVDEFGLPQ, corresponding to C terminal amino acids 202-215 of Human CHMP5 Entrez GeneID: ...
...
Biology Products: