Navigation Links
Researchers discover non-surgical test for brain cancer

Boston In a breakthrough for the way brain cancer is diagnosed and monitored, a team of researchers, lead by Anna M. Krichevsky, PhD, of the Center of Neurologic Diseases at Brigham and Women's Hospital (BWH) in Boston and Santosh Kesari, MD, PhD, director of Neuro-Oncology at UC San Diego Moores Cancer Center, have demonstrated that brain tumors can be reliably diagnosed and monitored without surgery. Previously, an accurate non-surgical test to detect brain tumors was unavailable and methods of monitoring a brain tumor's progression or response to treatment were not reliable. The results from this pilot study are published in the online edition of Neuro-Oncology.

"We are excited about the potential that this test has to ease the process of detecting and monitoring brain tumors," said Krichevsky. "The test needs to be further developed before it is used in a clinical setting, but I expect it could be particularly valuable for patients who are not surgical candidates due to the tumor's size or location, or due to an underlying medical condition."

In a study of 118 patients with different types of brain cancers, researchers showed that microRNA profiling of cerebrospinal fluid can be used to determine the presence of glioblastoma, the most common and lethal type of brain tumor. The test utilizes microRNAs, tiny RNA molecules that provide excellent biomarkers for various conditions, and whose levels can be accurately measured in body fluids simply and inexpensively. The same process can be used to detect the presence of cancer that started in another part of the body and spread to the brain, and furthermore, the process can also be used to monitor the tumor as it is treated.

A patent related to the test is pending. The study was funded by National Institutes of Health grants [R01CA138734-01A1, K08CA124804, and ARRA 3P30CA023100-25S8, the Sontag Foundation and the James S. McDonnell Foundation.


Contact: Tom Langford
Brigham and Women's Hospital

Page: 1

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
(Date:10/6/2015)... Oct. 6, 2015 Track Group, Inc. (OTCQX: ... it has signed a contract with the Virginia Department ... full range of sentences under the Department,s oversight. ... Americas. "This contract with the Virginia DOC will expand ... and advances our position as a trusted leader in ...
(Date:9/30/2015)... , Sept. 30, 2015  With nearly 300,000 ... number of new SCIs estimated to reach 12,500 annually, ... Southern California Resource Services for Independent Living (SCRS-IL) ... in California opening doors to ... of programs and services, notably assistive technology services and ...
(Date:9/28/2015)... YORK , Sept. 28, 2015 /PRNewswire/ ... announced today that its expedited traveler service ... innovative platform transforms travel, bringing a frictionless ... its members. "CLEAR offers our ... enhances customer service," said Jim Smith ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... Florida , October 13, 2015 ... specializing in the development of innovative peptide and gene-based ... metastatic disease, will be a featured presenting company at ... at the Wyndham Grand Hotel in Jupiter, ... TapImmune, Inc. (TPIV), a clinical-stage immunotherapy company ...
(Date:10/13/2015)... ... 2015 , ... Clinovo recently appointed Jeff Parr and Ed Donaldson to its ... solutions business. , Jeff Parr has spent the past decade providing quality management software ... Fisher, and Ab Sciex to name a few. He is based in Salt ...
(Date:10/13/2015)... -- the United States , ... about 14% of all new cases of kidney cancer.   ... and Europe .  PRCC represents about ... Hutchison China MediTech Limited ("Chi-Med") (AIM: HCM) today announces that ... (publ) ("AstraZeneca") have completed enrolment in a global Phase II study ...
(Date:10/12/2015)... , Oct. 12, 2015 This report covers ... include cell type, products, applications, end-user markets and geographic ... HIGHLIGHTS The global cell expansion market generated revenue ... to reach revenues of $9.7 billion in 2015 and ... rate (CAGR) of 17.8% from 2015 to 2020. ...
Breaking Biology Technology: