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Researchers discover how stealthy HIV protein gets into cells
Date:3/17/2008

ps on the membrane lipids in a way that caused the membrane to buckle in two different directions, bringing on the saddle splay curvature that allowed the pores to form.

When another positively charged amino acid, lysine, was used instead of arginine, the protein bent the membrane in one direction only, forming a shape more like a closed cylinder that would not allow materials to pass through.

These findings will aid researchers hoping to enhance the properties of the TAT protein that make it a good vehicle for transporting therapeutic molecules into cells, Wong said.

Wong also is a professor of physics and of bioengineering.


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Contact: Diana Yates
diya@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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Researchers discover how stealthy HIV protein gets into cells
Researchers discover how stealthy HIV protein gets into cells
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