Navigation Links
Researchers discover how key enzyme repairs sun-damaged DNA
Date:7/25/2010

that the electron and proton are automatically ejected out of the DNA helix and back into the photolyase, presumably so it could start the cycle over again and go on to heal other sites.

All plants and most animals have photolyase to repair severe sun damage. Everything from trees to bacteria to insects enjoys this extra protection. Only mammals lack the enzyme.

Humans do possess some enzymes that can undo damage with less efficiency. But we become sunburned when our DNA is too damaged for those enzymes to repair, and our skin cells die. Scientists have linked chronic sun damage to DNA mutations that lead to diseases such as skin cancer.

Now that researchers know the mechanism by which photolyase works, they might use that information to design drugs or lotions that heal sun damage, Zhong said.

Normal sunscreen lotions convert UV light to heat, or reflect it away from our skin. A sunscreen containing photolyase could potentially heal some of the damage from UV rays that get through.

Perhaps ironically, photolyase captures light of a different wavelength -- visible light, in the form of photons -- to obtain enough energy to launch the healing electron and proton into the DNA that has been damaged by UV light.

Researchers knew that visible light played a role in the process -- hence the term "photo" in the enzyme's name -- but nobody knew exactly how, until now.


'/>"/>

Contact: Dongping Zhong
Zhong.28@osu.edu
614-292-3044
Ohio State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... the bladders of healthy women differ from bacteria ... according to researchers from Loyola University Chicago Stritch ... July 9, 2014, in the American Society for ... bacterial communities may play a role in female ... a common, yet poorly understood, condition with symptoms ...
(Date:7/9/2014)... associate professor of plant pathology and microbiology ... the 2014 Alexopoulos Prize by the Mycological ... the science of mycology the study of fungi ... plant pathogens, and medically important fungi. , The award ... mycologist. Stajich received the award last month in East ...
(Date:7/9/2014)... As climate change shifts the geographic ranges in which ... it has on their parasites. Does an increased range ... as well? , Not necessarily, says a team of ... Armand Kuris. In a study published in the ... that for some species, the opposite may happen: Hosts ...
Breaking Biology News(10 mins):UC Riverside plant pathologist receives national recognition 2Not at home on the range 2Not at home on the range 3Not at home on the range 4
... COLUMBUS, Ohio Ohio State University cancer researchers ... brain-tumor cells and blocks the growth of new tumor ... to kill cancer cells oncolytic viruses might ... also carry a gene for a protein that inhibits ...
... NEW YORK, Dec. 1 iQor, a global provider of business ... 100 Awards Top 100 IT project of 2009 for its ... , "We are honored to be recognized among this prestigious list ... is completely transforming the way we do business, allowing us to ...
... bad cold, can spread among groups of people, research ... Diego and Harvard shows. Using longitudinal data from a ... more than 60 years, a team of scholars found ... others. Gradually over time, a group of lonely, disconnected ...
Cached Biology News:Tumor-attacking virus strikes with 'one-two punch' 2iQor Named to InfoWorld 100 List of Top IT Projects of 2009 2Loneliness can be contagious 2Loneliness can be contagious 3
(Date:1/14/2014)... January 14, 2014 iLab Solutions, the leader ... the new Director of Product Strategy. In this role, Michelle ... iLab sub-teams to guide in the development of iLab products. ... the maximum possible benefit to the scientific community by offering ...
(Date:1/14/2014)... 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), a ... innovative therapies addressing major unmet medical needs using ... Notice of Allowance from the United States Patent ... compounds (sd-rxRNA®), for the treatment of fibrosis. The ...
(Date:1/14/2014)... , Jan. 14, 2014   Kinaxis ®, provider of ... ) and sales and operations planning ( S&OP ) service, ... Biomanufacturing Summit , which will be held at the Hilton ... conference, join Kinaxis customer Elisabeth Kaszas , Director of ...
(Date:1/14/2014)... 14, 2014 Kerr Corporation, a leading manufacturer ... additional how-to information about dual arch impressions on its dental ... Arch Impressions,” the blog entry serves up a list of ... a step-by-step demonstration by Dr. David Little as he crafts ...
Breaking Biology Technology:iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... 1 Iomai Corporation,(Nasdaq: IOMI ) ... merger of,Iomai with a wholly-owned subsidiary of ... shares entitled to vote at the special,meeting ... of the,votes cast. The transaction remains subject ...
... MS, EDMONTON, Aug. 1 /PRNewswire-FirstCall/ - BioMS ... treatment of multiple sclerosis (MS), today,announced that it ... trial of MBP8298 (dirucotide) for the treatment of ... approximately,510 patients, and is being conducted at 68 ...
... Associates has announced the development of the Core Communications Program, ... investors, collaborators, and customers. , ... ... http://www.mainsgate.com [Mains Associates] has announced the availability of ...
Cached Biology Technology:BioMS Medical completes patient recruitment in phase III U.S. multiple sclerosis trial 2BioMS Medical completes patient recruitment in phase III U.S. multiple sclerosis trial 3BioMS Medical completes patient recruitment in phase III U.S. multiple sclerosis trial 4Bay-Area Company Gives Science-Based Startups a Voice 2
... 26] to Presenilin 2 Alzheimer's disease ... the disease carry mutations in the presenilin ... protein (APP). These disease-linked mutations result in ... amyloid-beta (main component of amyloid deposits found ...
One-step, microplate or cuvet, colorimetric, linear detection range 0.7 mg/dL to 35 mg/dL. Procedure: 5 min....
One-step, microplate or cuvet, colorimetric, linear detection range 0.9 mg/dL to 200 mg/dL. Procedure: 2 min....
[5,6,8,9,12,14,15(n)-3H]Prostaglandin D2, 925 kBq, 25 uCi. Methanol:water:acetonitrile (3:2:1) solution.> 3.0 TBq/mmol, > 80 Ci/mmol.3.7 MBq/ml, 100 uCi/ml. Category: Radiochemicals &Radiation Safety...
Biology Products: