Navigation Links
Researchers discover atomic bomb effect results in adult-onset thyroid cancer
Date:8/28/2008

PHILADELPHIA Radiation from the atomic bomb blasts in Hiroshima and Nagasaki, Japan, in 1945, likely rearranged chromosomes in some survivors who later developed papillary thyroid cancer as adults, according to Japanese researchers.

In the September 1, 2008, issue of Cancer Research, a journal of the American Association for Cancer Research, the scientists report that subjects who lived close to the blast sites, were comparably young at the time, and developed the cancer quickly once they reached adulthood, were likely to have a chromosomal rearrangement known as RET/PTC that is not very frequent in adults who develop the disease.

"Recent in vitro and in vivo studies suggest that a single genetic event in the MAP kinase-signaling pathway may be sufficient for thyroid cell transformation and tumor development," said the study's lead author, Kiyohiro Hamatani, Ph.D., laboratory chief, Department of Radiobiology and Molecular Epidemiology at the Radiation Effects Research Foundation (RERF) in Hiroshima.

"Thyroid cancer is associated with exposure to external or internal ionizing radiation.Elucidation of mechanisms of radiation-induced cancer in humans, especially early steps and pathways, has potential implications for epidemiological risk analyses, early clinical diagnosis, and chemopreventive interventions," Hamatani said.

He adds that there are several irradiated populations worldwide that have been shown to have an increase in thyroid cancer, and that children exposed to radioactive fallout from the 1986 Chernobyl nuclear power plant accident who develop papillary thyroid cancer have also been found to have RET/PTC rearrangements, although they are slightly different.

This study is part of the foundation's long running follow-up research on 120,000 atomic bomb survivors. During 1958 to 1998, the study found about 470 thyroid cancer cases of which the estimated number of excess cases attributable to radiatio
'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Antidepressants need new nerve cells to be effective, UT Southwestern researchers find
2. Indiana U researchers launch social networking and research management tool for scientists
3. UC Davis researchers define characteristics, treatment options for XXYY syndrome
4. Munich researchers discover key allergy gene
5. Rapid test for pathogens developed by K-State researchers
6. OU researchers isolate microorganisms that convert hydrocarbons to natural gas
7. UH researchers win top prize for research with humanitarian applications
8. Caltech researchers awarded $10M for molecular programming project
9. Researchers study facial structures, brain abnormalities to reveal formula for detection of autism
10. Mount Sinai researchers discover technology that silences genes
11. Researchers link cocoa flavanols to improved brain blood flow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... TX Invasives is now available from the Lady Bird ... Austin for identifying harmful non-native plant, insect and other ... United States cause about $137 billion in economic and ... waterways, kill native plants and more. , "By having ... where invasive species occur, we,re more likely to catch ...
(Date:8/28/2014)... Yale University researchers have identified a handful of bacterial ... as Crohn,s disease and ulcerative colitis, using patients, own ... are published Aug. 28 in the journal Cell ... intestinal microbiota, which plays a critical role in the ... only a small number of bacterial species affect a ...
(Date:8/28/2014)... This news release is available in German . ... fresh water fish, owes its name to a striking pattern ... cell types, black cells, reflective silvery cells, and yellow cells ... fish and arrange as a multilayered mosaic to compose the ... all three cell types have to interact to form proper ...
Breaking Biology News(10 mins):Mobile app makes ID of harmful plants, insects in Texas a snap 2Yale study identifies possible bacterial drivers of IBD 2How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3
... be developed for detecting SCID (primary immunodeficiency) in newborns ... at the New York Academy of Sciences' and Jeffrey ... The meeting will take place on April 25 ... from 8 a.m. to 5:30 p.m. Thirty of ...
... too when there's no picture in this kind of article ... plays a key role in activating the Epstein Barr Virus ... the European Molecular Biology Laboratory (EMBL) and the Institut de ... Fourier and the CNRS, in Grenoble. , Like Sleeping Beauty, ...
... nearly 5 percent of pneumonia patients in rural Thailand, ... Centers for Disease Control and Prevention report their findings ... , "Our preliminary data suggests that human bocavirus may ... children," says Alicia Fry, one of the researchers on ...
Cached Biology News:First SCID gene chip to be introduced at Academy meeting on immunodeficiencies 2First SCID gene chip to be introduced at Academy meeting on immunodeficiencies 3Waking a sleeping virus 2Bocavirus infection may be associated with pneumonia in Thailand, especially in children 2
(Date:8/29/2014)... , Aug. 29, 2014 /PRNewswire/ - iCo ... ICOTF), today reported financial results for the six ... otherwise, are expressed in Canadian dollars and presented ... Second Quarter 2014 Highlights , Announced ... acuity (VA) primary endpoint for subjects enrolled in ...
(Date:8/29/2014)... Boston, MA (PRWEB) August 29, 2014 ... ones in the biotech start-up dense realm of Boston-Cambridge, ... alliances and able investors. James Sherley, the Director of ... made increasing the local and national visibility of his ... in September 2013. , In addition to a social ...
(Date:8/28/2014)... Best Sanitizers, Inc., the first company ... sanitizer, asks food processors and food handling professionals to ... they’re currently using to Best Sanitizers’ Alpet® E3 ... to fighting cross-contamination and the spread of pathogens in ... are key criteria that make a hand sanitizer most ...
(Date:8/28/2014)... , Aug. 28, 2014 /PRNewswire/ ... new market research report is ... Whole Exome Sequencing Market ... Preparation, Target Enrichment), by Services ... Synthesis), by Application (Cancer, Monogenic ...
Breaking Biology Technology:iCo Therapeutics Announces Second Quarter 2014 Financial Results 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 3iCo Therapeutics Announces Second Quarter 2014 Financial Results 4The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 3Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 4Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 5Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 6Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 7Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 8Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 9Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 10Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 11Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 12Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 13
... Update, by WTN's Mike Klein: The Wisconsin Alumni Research Foundation ... its contributions to technology transfer. Wingra Technologies has been ... Wave Technologies has posted improved financial results for the past ... Listen to this episode Read ...
... addicts, take heart: A public-private effort is moving toward ... AOL-SkyCable has been chosen to enter negotiations for ... the general public. The "Wireless Wisconsin" service would create ... and the Dane County Regional Airport. The project also ...
... Mondays Wall Street Journal detailed the news of ... talked about the consolidation of the Japanese pharma industry. The ... both American and European companies have been consolidating for years ... that the only company above that did not ...
Cached Biology Technology:Madison wi-fi plans move ahead 2Japan's pharma mergers will trickle to the Midwest 2Japan's pharma mergers will trickle to the Midwest 3Japan's pharma mergers will trickle to the Midwest 4
Anti-G-alpha-i 1 G-Protein Host: mouse monoclonal Species Reactivity: human, mouse, rat Applications: WB Storage: 4C...
WIF-1 (N-20)...
Mouse monoclonal [1.T.4] to WAVE 1 ( Abpromise for all tested applications). Antigen: His6 fusion protein corresponding to full-length rat WAVE1. Entrez Gene ID: 8936...
IgG2b, k APC clone A95-1, Isotype Rat IgG2b, kappa, 0.1 mg ....
Biology Products: