Navigation Links
Researchers develop new ultrasensitive assay to detect most poisonous substance known
Date:5/1/2008

DUARTE, Calif. -- Scientists at City of Hope and the California Department of Public Health have developed a new ultrasensitive assay to detect botulinum neurotoxin. The toxin is one of the most poisonous substances known that can cause life-threatening disease, and is considered a major potential bioterrorism threat agent. The research teams work is published today in the online journal PLoS ONE (http://www.plosone.org/doi/pone.0002041).

Botulinum neurotoxin is produced by the bacterium Clostridium botulinum. When ingested, the toxin disables nerve function and can result in paralysis and even death. Botulism normally results when a person eats food tainted with C. botulinum bacteria or if a wound is infected by the bacterium. Infants, whose digestive systems are not yet fully developed, also are susceptible to the disease if the bacterium gains a foothold in their intestinal tract. The Centers for Disease Control and Prevention identify botulinum neurotoxin as one of six maximum threat bioterrorism agents due to its potency, lethality and ease of production and transport. One gram of botulinum toxin could kill more than 1 million people, according to a 2001 study in the Journal of the American Medical Association.

The new test is at least ten thousand times more sensitive and produces results much faster than the current detection method for botulinum neurotoxin, said Markus Kalkum, Ph.D., assistant professor, Division of Immunology, City of Hope, and lead researcher in the study. Wide use of the new assay would improve food safety and food processing technology, speed up and improve the diagnosis and treatment of human disease, advance the development of novel therapeutics, and greatly enhance the countrys ability to detect and defend against a bioterrorism attack.

The collaborative research team developed a test that is less expensive, faster and easier to perform than c
'/>"/>

Contact: Shawn Le
sle@coh.org
800-888-5323
Public Library of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. USC School of Dentistry researchers uncover link between osteoporosis drugs and jaw infection
2. UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells
3. Researchers discover molecular basis of a form of muscular dystrophy
4. Sunflower debate ends in Mexico, researchers say
5. Carnegie Mellon researchers urge development of low carbon electricity
6. In computer models and observations, researchers see potential for significant red tide season
7. Montana State researchers study spread of lake trout in Glacier National Park
8. Medical College researchers find dinosaur clues in fat
9. Researchers discover gene for branchio-oculo-facial syndrome
10. Researchers reveal structure of protein that repairs damage to cancer cells
11. Purdue researchers propose way to incorporate deforestation into climate change treaty
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition of ... report to their offering. One ... adoption of multimodal biometric systems. Multimodal biometric systems ... for verification and identification purposes. This helps to ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here before: ... but can,t remember your password, site key or the answer ... your first grade teacher? Today, Hoyos ... app that will finally put an end to the ... 1U TM . 1U leverages a user,s smartphone to ...
(Date:12/10/2014)... 2014 CIE San Diego has launched an ... connective tissue that enhances care coordination among social service ... client-level information; earned a second $1 million grant from ... seniors aging in community and; will be recognized as ... th 4-6p. CIE San Diego today ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... Materials engineers have created a new type of membrane ... be used for environmental cleanup, water purification and industrial ... conventional filters for separating oil from water and works ... usually mutually exclusive. Researchers attached the material to a ...
... the Netherlands Royal Academy of Arts and Sciences (KNAW) ... a new research programme: the Joint Scientific Thematic Research ... and the Academy will work together on developing bilateral ... and the Academy launched the joint research programme during ...
... Journal of Preventive Medicine special issue on climate ... Climate Changing People" conference today in Los Angeles. ... MD, DrPH, speaking about the impacts of climate change ... public health challenge. Health professionals need to understand the ...
Cached Biology News:New filtering technology has environmental, industrial applications 2New filtering technology has environmental, industrial applications 3NWO and Academy launch research program with China 2Issues at intersection of climate change and health impact global well-being 2Issues at intersection of climate change and health impact global well-being 3Issues at intersection of climate change and health impact global well-being 4
(Date:12/17/2014)... 16, 2014 “Never say, ‘I ... Universität Marburg’s Department of Physics, advises young women ... newly released SPIE Women in Optics 18-month ... shy to ask questions.” , In the annual ... mathematics) occupations ranging from university professor and laboratory ...
(Date:12/17/2014)... BASKING RIDGE, N.J. (PRWEB) December 17, 2014 ... Ipsen (Euronext: IPN; ADR: IPSEY), ... 120 mg (referred to as Somatuline®) was approved ... for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) ... differentiated, locally advanced or metastatic disease to improve ...
(Date:12/17/2014)... This report is a professional ... For an overview analysis, the report introduces quartz ... structure, industry overview, policy analysis, and news analysis, ... has witnessed rapid development with key manufacturers increasing ... report mentions quartz tubing upstream raw materials and ...
(Date:12/17/2014)... December 17, 2014 Gene synthesis ... it has entered into a technology access and ... to apply DNA2.0’s proprietary protein engineering technology, known ... , “We are extremely excited that the global ... This proprietary bioengineering technology has now been ...
Breaking Biology Technology:Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 82020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2
... /PRNewswire-FirstCall/ - Oncothyreon Inc. (NASDAQ: ONTY ) (TSX: ONY) ... basic and diluted share, for the three months ended June 30, ... per basic and diluted share, for the comparable period in 2008. ... months ended June 30, 2009 for the change in the fair ...
... , , , ... Accera, Inc., a biotechnology company delivering breakthrough therapies in central ... paper in the peer-reviewed journal Nutrition & Metabolism . ... mild to moderate Alzheimer,s disease: a randomized, double-blind, placebo-controlled, multicenter ...
... , , , ... Cempra Pharmaceuticals today announced the appointment of John H. ... of Eli Lilly and Company, to the company,s Board of ... executive and operational management experience, including leadership of successful anti-infective ...
Cached Biology Technology:Oncothyreon reports second quarter 2009 financial results 2Oncothyreon reports second quarter 2009 financial results 3Oncothyreon reports second quarter 2009 financial results 4Oncothyreon reports second quarter 2009 financial results 5Oncothyreon reports second quarter 2009 financial results 6Oncothyreon reports second quarter 2009 financial results 7Accera Announces Peer-Reviewed Publication of the Results of its 90-Day Clinical Study of AC-1202 (Axona(TM) ) in Mild to Moderate Alzheimer's Disease 2Accera Announces Peer-Reviewed Publication of the Results of its 90-Day Clinical Study of AC-1202 (Axona(TM) ) in Mild to Moderate Alzheimer's Disease 3Cempra Pharmaceuticals Announces Appointment of John H. Johnson to Board of Directors 2Cempra Pharmaceuticals Announces Appointment of John H. Johnson to Board of Directors 3
APG5 autophagy 5-like (S. cerevisiae)...
Human Jagged 2 Biotinylated Affinity Purified PAb...
Mouse/Rat WNK1 Affinity Purified Polyclonal Ab...
Griess Reagent component for determination of nitrite in aqueous solutions....
Biology Products: