Navigation Links
Researchers develop new method for creating tissue engineering scaffolds
Date:2/10/2012

Researchers at Northwestern University have developed a new method for creating scaffolds for tissue engineering applications, providing an alternative that is more flexible and less time-intensive than current technology.

A paper describing the results, "Low-Pressure Foaming: A Novel Method for the Fabrication of Porous Scaffolds for Tissue Engineering," was featured in the February issue of the journal Tissue Engineering.

Through tissue engineering, researchers seek to regenerate human tissue, such as bone and cartilage, that has been damaged by injury or disease. Scaffolds artificial, lattice-like structures capable of supporting tissue formation are necessary in this process to provide a template to support the growing cells. Over time, the scaffold resorbs into the body, leaving behind the natural tissue.

Scaffolds are typically engineered with pores that allow the cells to migrate throughout the material. The pores are often created with the use of salt, sugar, or carbon dioxide gas, but these additives have various drawbacks; They create an imperfect pore structures and, in the case of salt, require a lengthy process to remove the salt after the pores are created, said Guillermo Ameer, professor of biomedical engineering at the McCormick School of Engineering and professor of surgery at the Feinberg School of Medicine.

The new scaffolds, created from a combination of ceramic nanoparticles and elastic polymers, were formed in a vacuum through a process termed "low-pressure foaming" that requires high heat, Ameer said. The result was a series of pores that were highly interconnected and not dependent on the use of salt.

The new process creates scaffolds that are highly flexible and can be tailored to degrade at varying speeds depending on the recovery time expected for the patient. The scaffolds can also incorporate nano-sized fibers, providing a new range of mechanical and biological properties, Ameer said.

"The technology could prove very useful in repairing ACL (anterior cruciate ligament) tears and in bone void fillers," Ameer said.


'/>"/>

Contact: Pat Vaughan Tremmel
p-tremmel@northwestern.edu
847-491-4892
Northwestern University
Source:Eurekalert

Related biology news :

1. No entry without protein recycling: RUB researchers discover new coherence in enzyme transport
2. Biodiversity enhances ecosystems global drylands -- Ben-Gurion U researchers
3. Boston University researchers develop novel drug delivery system
4. MSU researchers show how new viruses evolve, and in some cases, become deadly
5. Researchers show how viruses evolve, and in some cases, become deadly
6. Berkeley Lab researchers discover critical rotational motion in cells
7. CU School of Medicine researchers look at effects of 2 common sweeteners on the body
8. Researchers develop gene therapy that could correct a common form of blindness
9. Researchers meet to refine carbon budget for US East Coast
10. Penn researchers help solve questions about Ethiopians high-altitude adaptations
11. Notre Dame researchers report fundamental malaria discovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... Florida , April 11, 2017 ... a security technology company, announces the appointment of independent Directors ... Bendheim to its Board of Directors, furthering the company,s ... ... of NXT-ID, we look forward to their guidance and benefiting ...
(Date:4/5/2017)... 2017  The Allen Institute for Cell Science today ... one-of-a-kind portal and dynamic digital window into the human ... first application of deep learning to create predictive models ... and a growing suite of powerful tools. The Allen ... future publicly available resources created and shared by the ...
(Date:4/5/2017)... KEY FINDINGS The global market ... CAGR of 25.76% during the forecast period of 2017-2025. ... for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is segmented ... The stem cell market of the product is segmented ...
Breaking Biology News(10 mins):
(Date:4/28/2017)... ... April 28, 2017 , ... While things have been quiet for ... company and provide a new outlook for the future. As a continued effort ... management with the retirement of Mr. Siegel as CEO. With the new adjustments in ...
(Date:4/27/2017)... ... April 27, 2017 , ... ... digital pathology, today announced their digital pathology technology has the potential to eliminate ... five medical centers in The Netherlands as part of the 2017 ISBI ...
(Date:4/27/2017)... ... April 27, 2017 , ... During the course ... how testing for 1,25-Dihydroxyvitamin D can enhance clinical practice. Participants will learn the ... dihydroxyvitamin D. , Dr. Gregory Plotnikoff, senior consultant with Minnesota Personalized Medicine, will ...
(Date:4/27/2017)... ... 27, 2017 , ... The Council for Agricultural Science and ... Lusk, a consummate communicator who promotes agricultural science and technology in the public ... explains how innovation and growth in agriculture are critical for food security and ...
Breaking Biology Technology: