Navigation Links
Researchers develop new method for analyzing cell function
Date:6/26/2012

Researchers in Finland and Germany have developed an open-source software that will make it significantly easier to process bioimaging data. The software, named BioImageXD, will help in analysing cell and tissue functions. The work to develop the software has been funded by the Academy of Finland (through the FinNano Research Programme), the European Union and Tekes the Finnish Funding Agency for Technology and Innovation. Version 1.0 of BioImageXD has been accepted for publication in Nature Methods, the top journal in the field.

Among other things, the BioImageXD software is a tool for analysing how molecules move on cell surfaces and how they bond together. With the software, scientists can analyse the composition of cell surfaces, study how cancer cells spread in a three-dimensional environment, or measure how effectively viruses and targeted drugs enter cells. Such calculations have not been possible before.

In recent years, cell and tissue imaging with new, specialised microscopes has considerably advanced research in bioscience and biomedicine. The new methods also allow for studies on living cells. However, the microscopic images are not displayable as such and need to be rendered into three-dimensional models. These 3D renderings carry significant weight as evidence already by themselves, but reliable scientific data also requires numerical values, which can then be used in mathematical calculations. In addition, these calculations must be feasible with extremely large datasets.

So far, the lack of suitable software has clogged up this development. To solve the problem, researchers in Turku, Jyvskyl and Dresden drew up precise specifications for software for processing of imaging data. A key criterion was that the software would be based on the principles of open source, freely available to all researchers.

The work resulted in BioImageXD, a software program that thanks to its versatile and open-source nature has received much positive feedback from hundreds of researchers around the world.

From extensive development to test success

One of the unique features of BioImageXD is that it can be used to create completely new analysis methods (and users do not even need programming skills), process thousands of images at the same time and analyse millions of molecules. Comparison tests have shown that BioImageXD is faster and more sensitive than other similar programs.

The development of the BioImageXD software began ten years ago in a University of Jyvskyl research team led by Jyrki Heino. Since then, the work has continued through active collaboration between Heino's team, Varpu Marjomki's team and Daniel White from Max Planck Institute of Molecular Cell Biology and Genetics.

The main development has been led by Pasi Kankaanp, who now works at Turku Centre for Biotechnology as Coordinator of the Cell Imaging Core.

The BioImageXD software will be featured in a special issue of Nature Methods, focusing on the processing of biomedical images.


'/>"/>

Contact: Pasi Kankaanp
pkanka@utu.fi
358-405-221-090
Academy of Finland
Source:Eurekalert

Related biology news :

1. Maths formula leads researchers to source of pollution
2. 7 pharmaceutical companies join academic researchers to speed TB drug discovery
3. Researchers advance biometric security
4. Argonne researchers receive 4 R&D 100 awards
5. Researchers identify need to sample multiple tumor zones in breast cancer
6. London researchers discover novel mechanism involved in key immune response
7. NTU researchers study little mighty creature for scientific breakthrough
8. UTMB researchers create powerful new method to analyze genetic data
9. Researchers at GW receive federal funds to study the effect earthquakes have on nuclear reactors
10. Stanford researchers help predict the oceans of the future with a mini-lab
11. Researchers complete the first epigenome in Europe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... India , March 23, 2017 The report "Gesture ... Touchless Biometric), Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, ... at a CAGR of 29.63% between 2017 and 2022. ... ... ...
(Date:3/22/2017)... March 21, 2017 Vigilant Solutions , ... law enforcement agencies, announced today the appointment of retired ... of public safety business development. Mr. Sheridan ... experience, including a focus on the aviation transportation sector, ... recent position, Mr. Sheridan served as the Aviation Liaison ...
(Date:3/13/2017)... , March 13, 2017 Future of security: Biometric ... ... DERMALOGs Face Matching enables to match face pictures ... the basis to identify individuals. (PRNewsFoto/Dermalog Identification Systems) ... DERMALOG,s "Face Matching" is the fastest software for biometric Face ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... RESEARCH TRIANGLE PARK, N.C. , April 27, ... UTHR ) today announced that its Board of Directors ... the company,s common stock. This program will became effective ... Purchases may be made in the open market, accelerated ... to time as determined by United Therapeutics, management and ...
(Date:4/27/2017)... SEATTLE, WA (PRWEB) , ... April 27, 2017 ... ... a revolutionary, cloud-based and secure electronic informed consent (eConsent) solution that simplifies research ... the technology and consulting division of Quorum, Q Consent™ is the first ...
(Date:4/27/2017)... ... April 27, 2017 , ... ... name change to Fluence Analytics. , Fluence Analytics provides proprietary hardware ... biopharmaceutical manufacturing processes and R&D applications. The company’s patented technologies improve production ...
(Date:4/27/2017)... a distinguished resource for research, development and commercialization of ... Thomas C. Seoh as President and CEO. Mr. Seoh ... becomes Executive Chairman and will continue to serve as ... Thomas Seoh commented, "I am excited and honored ... firm,s remarkable team of life science professionals, all of ...
Breaking Biology Technology: