Navigation Links
Researchers develop nano-sized 'cargo ships' to target and destroy tumors
Date:9/11/2008

Scientists have developed nanometer-sized 'cargo ships' that can sail throughout the body via the bloodstream without immediate detection from the body's immune radar system and ferry their cargo of anti-cancer drugs and markers into tumors that might otherwise go untreated or undetected.

In a forthcoming issue of the Germany-based chemistry journal Angewandte Chemie, scientists at UC San Diego, UC Santa Barbara and MIT report that their nano-cargo-ship system integrates therapeutic and diagnostic functions into a single device that avoids rapid removal by the body's natural immune system. Their paper is now accessible in an early online version at: http://www3.interscience.wiley.com/journal/121376053/abstract?CRETRY=1&SRETRY=0

"The idea involves encapsulating imaging agents and drugs into a protective 'mother ship' that evades the natural processes that normally would remove these payloads if they were unprotected," said Michael Sailor, a professor of chemistry and biochemistry at UCSD who headed the team of chemists, biologists and engineers that turned the fanciful concept into reality. "These mother ships are only 50 nanometers in diameter, or 1,000 times smaller than the diameter of a human hair, and are equipped with an array of molecules on their surfaces that enable them to find and penetrate tumor cells in the body."

These microscopic cargo ships could one day provide the means to more effectively deliver toxic anti-cancer drugs to tumors in high concentrations without negatively impacting other parts of the body.

"Many drugs look promising in the laboratory, but fail in humans because they do not reach the diseased tissue in time or at concentrations high enough to be effective," said Sangeeta Bhatia, a physician, bioengineer and professor of Health Sciences and Technology at MIT who played a key role in
'/>"/>

Contact: Kim McDonald
kimmcdonald@ucsd.edu
858-534-7572
University of California - San Diego
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Gap junction protein vital to successful pregnancy, researchers find
2. Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
3. Researchers seeking to identify Alzheimers risk focus on specific blood biomarker
4. ISU researchers help map first plant-parasitic nematode genome sequence
5. Collaboration between researchers yields more comprehensive portrait of brain cancer
6. Tel Aviv University researchers create new stem cell screening tool
7. Hopkins researchers piece together gene network linked to schizophrenia
8. TGen and Washington University researchers discover new approach to treating endometrial cancer
9. Researchers devise means to create blood by identifying earliest stem cells
10. Researchers discover atomic bomb effect results in adult-onset thyroid cancer
11. Antidepressants need new nerve cells to be effective, UT Southwestern researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers develop nano-sized 'cargo ships' to target and destroy tumors
(Date:5/11/2015)... May 11, 2015 Curemark LLC, a privately ... of a new Phase III double blind, randomized, placebo-controlled ... formulation, CM-AT, on all children ages 3-8 with Autism. ... Phase III double blinded clinical trial for CM-AT in ... of the digestive enzyme chymotrypsin. This new trial will ...
(Date:5/6/2015)... TEL AVIV, Israel , May 6, 2015 /PRNewswire/ ... the world,s most established helmet producer, announced today that ... LifeBEAM Smart Helmet, the world,s first bio-sensing cycling helmet ... will be released in two new colors in order ... demand for the product. In addition, LifeBEAM and Lazer ...
(Date:4/27/2015)... Profile Solutions, Inc. (OTC: PSIQ), a leading ... pleased to announce that Dr Gerry Bedore ... of its scientific advisory board. ... leader in technology-enhanced learning models. He was a co-founder ... studies and books focused on online student success and ...
Breaking Biology News(10 mins):Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... of the patients who received injections of steroids contaminated ... Compounding Center has found that some patients had fungal ... of their symptoms and that magnetic resonance imaging (MRI) ... received injections from highly contaminated lots. The ...
... extremely disappointed that the European Chemicals Agency (ECHA) Board ... Benelux B.V.to conduct a pre-natal developmental toxicity study in ... expose pregnant rats and their unborn pups to the ... to comply with the European Community,s Regulation on the ...
... are threatened with extinction as a result of rising human ... Ohio State University in the US. Their work is also ... human population will continue to pose a threat to other ... a threshold above which population growth would cease to have ...
Cached Biology News:Evolution of an outbreak: Complications from contaminated steroid injections 2Are we pushing animals over the edge? 2
(Date:5/28/2015)... 27, 2015 Research and Markets( http://www.researchandmarkets.com/research/6cg3zw/cell_therapy ... new report "Cell Therapy - Technologies, Markets ... This report describes and evaluates cell therapy technologies ... an important role in the practice of medicine. ... fashioned bone marrow transplants. Role of cells in ...
(Date:5/28/2015)... 28, 2015 DryLet, LLC a ... applications such as animal waste reduction, bioremediation, wastewater ... in wastewater treatment plants and restaurant kitchen settings, ... Pork Expo, June 3-5 in Des Moines, Iowa. ... a Wall Street Journal article because of its ...
(Date:5/28/2015)... , May 28, 2015  GenVec, Inc. (Nasdaq: ... CEO, Douglas J. Swirsky , will present a ... at 11 a.m. EDT on Thursday, June 4, 2015. ... Mr. Swirsky,s presentation will be available at the following ... available on GenVec,s website.  To access, visit www.genvec.com ...
(Date:5/28/2015)... Minneapolis, MN (PRWEB) May 28, 2015 ... makes it a point to ask his audiences ... of future trends including robotics, solar cells, fuel ... sequencing, 3D printers, advanced battery storage technology, driverless ... assistants, and high-quality but inexpensive online education. ...
Breaking Biology Technology:Global Cell Therapy Market 2015-2020 - Technologies, Markets and Companies 2DryLet to Showcase Patented ManureMagicâ„¢ at the 2015 World Pork Expo, June 3-5 in Des Moines, Iowa 2GenVec To Present At The Jefferies Healthcare Conference 2Futurist Jack Uldrich to Deliver 4 Keynote Addresses in June 2
... Corporation,(Nasdaq: CRVL ), a leading provider of ... over 150,000 facility and,provider locations to its national ... new provider network additions are the,result of a ... St. Petersburg, FL. With more than 5,500 ...
... The following statement,was issued today by the law firm of ... that a class action lawsuit was filed in the,United States ... of,all purchasers of securities of LCA-Vision, Inc. (Nasdaq: LCAV ... 30, 2007, inclusive (the,"Class Period"). If you wish to ...
... AviaraDx announced today that,the company,s Carlsbad, CA, ... Pathology (CAP) accreditation. The laboratory offers,two new molecular ... States. CancerTYPE ID(TM) is a 92-gene expression ... ID(TM) provides a molecular classification of metastatic,cancer and ...
Cached Biology Technology:CorVel Corporation Medical Provider Network Adds New Providers to Increase Savings and Improve Access to Care 2CorVel Corporation Medical Provider Network Adds New Providers to Increase Savings and Improve Access to Care 3Shareholder Class Action Filed Against LCA-Vision, Inc. by the Law Firm of Schiffrin Barroway Topaz & Kessler, LLP 2Shareholder Class Action Filed Against LCA-Vision, Inc. by the Law Firm of Schiffrin Barroway Topaz & Kessler, LLP 3AviaraDx Announces CAP Accreditation of Its Laboratory Operations 2
...
...
...
... submicron range are part of your production ... of particle size is important to you. ... detect the component populations in your sample ... Analyzer uses Photon Correlation Spectroscopy (PCS) , ...
Biology Products: