Navigation Links
Researchers develop method to grow artificial tissues with embedded nanoscale sensors
Date:8/26/2012

Boston, Mass.A multi-institutional research team has developed a method for embedding networks of biocompatible nanoscale wires within engineered tissues. These networkswhich mark the first time that electronics and tissue have been truly merged in 3Dallow direct tissue sensing and potentially stimulation, a potential boon for development of engineered tissues that incorporate capabilities for monitoring and stimulation, and of devices for screening new drugs.

The researcher teamled by Daniel Kohane, MD, PhD, in the Department of Anesthesia at Boston Children's Hospital; Charles M. Lieber, PhD, at Harvard University; and Robert Langer, ScD, at the Massachusetts Institute of Technologyreported their work online on August 26 in Nature Materials.

One of the major challenges in developing bioengineered tissues is creating systems to sense what is going on (e.g., chemically, electrically) within a tissue after it has been grown and/or implanted. Similarly, researchers have struggled to develop methods to directly stimulate engineered tissues and measure cellular reactions.

"In the body, the autonomic nervous system keeps track of pH, chemistry, oxygen and other factors, and triggers responses as needed," Kohane explained. "We need to be able to mimic the kind of intrinsic feedback loops the body has evolved in order to maintain fine control at the cellular and tissue level."

With the autonomic nervous system as inspiration, a postdoctoral fellow in the Kohane lab, Bozhi Tian, PhD, and his collaborators built mesh-like networks of nanoscale silicon wiresabout 80 nm in diametershaped like flat planes or in a "cotton-candy"-like reticular conformation. The networks were porous enough to allow the team to seed them with cells and encourage those cells to grow in 3D cultures.

"Previous efforts to create bioengineered sensing networks have focused on 2D layouts, where culture cells grow on top of electronic components,
'/>"/>

Contact: Keri Stedman
keri.stedman@childrens.harvard.edu
617-919-2110
Boston Children's Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
4. UNH researchers find African farmers need better climate change data to improve farming practices
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. Researchers print live cells with a standard inkjet printer
8. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
9. Researchers reveal how a single gene mutation leads to uncontrolled obesity
10. Researchers discover novel therapy for Crohns disease
11. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/8/2015)... Calif. , May 8, 2015 Synaptics Inc. ... solutions, today announced that members of the executive management team ... Morgan 43rd Annual Technology, Media and Telecom Conference Date: ... Hotel in Boston, MA ... 27, 2015 Time: 2:45pm ET Location: The New York Palace ...
(Date:4/27/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces that its ... the first week of May, 2015 and will be ... Gino Pereira , Chief Executive ... company as Wocket® enters the consumer market. We would ...
(Date:4/17/2015)... 2015 Increasing adoption ... advancement to drive biometric systems market in ... According to a recently released TechSci ... ", biometric systems market in Saudi ... at CAGR of over 22% through 2020. The ...
Breaking Biology News(10 mins):Synaptics to Present at Upcoming Investor Conferences 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... Washington, D.C. (October 5, 2010) -- Carbon nanotubes -- ... in diameter -- have many potential uses in nanotechnology, ... of nanotubes depend on their structure, and scientists as ... determined during the initial formation -- or growth -- ...
... BOZEMAN, Mont. -- Montana State University researchers have discovered a ... geothermal vents at the bottom of Yellowstone Lake. A ... in an area where the water is inky black, about ... poisons, the researchers reported in the September issue of Geobiology. ...
... toxic pollution falling onto Puget Sound,s waters has decreased ... below earlier estimates, according to a region-wide study. Despite ... like Tacoma still have the Puget,s Sound,s highest air-deposited ... of Energy,s Pacific Northwest National Laboratory and Texas A&M ...
Cached Biology News:The effects of hydrogen on growing carbon nanotubes 2Montana State team finds rare oasis of life on floor of Yellowstone Lake 2Montana State team finds rare oasis of life on floor of Yellowstone Lake 3Montana State team finds rare oasis of life on floor of Yellowstone Lake 4The sky is falling (less) onto Puget Sound 2The sky is falling (less) onto Puget Sound 3The sky is falling (less) onto Puget Sound 4
(Date:5/28/2015)... , May 28, 2015 Natera, ... announced a study published in Ultrasound in ... single-nucleotide polymorphism (SNP)-based non-invasive prenatal test (NIPT) can ... trimester. A study based upon ... molar pregnancies occur in about 1 in 1,000 ...
(Date:5/28/2015)... 28, 2015 RXi Pharmaceuticals Corporation (NASDAQ: ... developing innovative therapeutics, primarily in the areas of dermatology ... offering of 26 million units at a price to ... of approximately $10.4 million. Each unit consists of (i) ... purchase right to purchase 0.50 of a share of ...
(Date:5/28/2015)... The Fertility Centers of New England is proud to ... on a new and expanded role as Medical Director. ... oversight and quality assurance for the practice. , “We ... of experienced reproductive endocrinologists,” said Fertility Centers of New ... expertise and compassionate, individualized care have helped set FCNE ...
(Date:5/28/2015)... Atlanta, Georgia (PRWEB) May 28, 2015 ... Ridge National Laboratory (Oak Ridge, TN) recently ... strength of 3D printing plastic resins using nanocellulose, ... well-known constraint of 3D printing is the limited ... resins provide inadequate mechanical strength to printed parts ...
Breaking Biology Technology:First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 3RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 3Danielle Vitiello, MD of Fertility Centers of New England, Named New Medical Director 2American Process Inc. Announces Partnership with Oak Ridge National Laboratory to Make 3D Printing Plastic Resins Stronger and More Sustainable 2American Process Inc. Announces Partnership with Oak Ridge National Laboratory to Make 3D Printing Plastic Resins Stronger and More Sustainable 3
... OREX ), a biopharmaceutical company focused on ... Patent and Trademark Office,(USPTO) has issued a patent for ... (U.S. Patent No. 7,462,626), which provides,coverage for Contrave(R), the ... trials. , The patent broadly ...
... BELGIUM, Wis., Jan. 5 Mach One Corporation,(Pink Sheets: ... a positive long term benefit to the agricultural and ... non-binding letter of,intent dated December 30, 2008 related to ... BioPharm) (the "Seller" or "BioPharm") to,acquire all of the ...
... of Norton & Associates with Divisions in NORTECH ... Carbon Credit Today. The group,s announcement of a ... private equity land investments and the acquisition funding ... commercial market conditions, Norton & Associates Inc. provides ...
Cached Biology Technology:Orexigen(R) Therapeutics Issued a Key Fourth U.S. Patent on Contrave(R) 2Orexigen(R) Therapeutics Issued a Key Fourth U.S. Patent on Contrave(R) 3Mach One Corporation Enters Letter of Intent 2Norton & Associates Inc. Adds $3bnUSD Commercial Real Estate Investment P & L Management Holding Group; US Property Portfolio Inc. 2
ABgene® supplies a 94kDa ultra-pure recombinant thermostable DNA polymerase obtained by high level expression of the Taq DNA polymerase gene in E. coli....
From formula-fed bovine calves Sterile, Cell culture tested...
... Taq DNA Polymerase is a thermostable ... Having optimal activity at temperatures above ... enzyme used for PCR and remains ... The enzyme has an intrinsic 5'?3' ...
Mouse monoclonal [YPF19] to Yersinia pestis F1 antigen ( Abpromise for all tested applications)....
Biology Products: