Navigation Links
Researchers develop genetic control mechanism for major livestock pest
Date:6/19/2014

Researchers from North Carolina State University have developed a technique to control populations of the Australian sheep blowfly a major livestock pest in Australia and New Zealand by making female flies dependent upon a common antibiotic to survive.

Dr. Max Scott, professor of entomology at NC State, and his research team genetically modified lines of female Australian sheep blowflies (Lucilia cuprina) so that they required doses of tetracycline in order to live. Female blowflies that did not receive the antibiotic died in the late larval or pupal stages, before reaching adulthood. Several genetically modified lines lacking tetracycline showed 100 percent female deaths.

Scott says that the gene construct responsible for lethality in antibiotic-free diets is female-specific. Interestingly and unexpectedly, the genetically modified female larvae containing the tetracycline lethality genes also took on a crimson color due to overexpression of the linked red fluorescent protein "marker gene." This allows scientists to tell which larvae will be females and which will be males.

"Overexpression of the gene responsible for the reliance on tetracycline also seems to overexpress this marker gene," Scott says.

Since the females will die when not provided tetracycline in their diets, the males can be separated out in the larval stage. This is essential for a "male-only" genetic control program to reduce blowfly populations, Scott says, as fertile males would pass the lethality construct on to female offspring, which would die in the absence of tetracycline. Male larval offspring, however, would still be dangerous to livestock.

In the study, the researchers showed that the tetracycline gene construct also works in Drosophila, the fruit fly "lab rat" of the insect world that is a distant cousin of the sheep blowfly. This holds promise that the genetic system will function in the New World and Old World screwworm, two major livestock pests that are close relatives of the sheep blowfly. Scott is working with the U.S. Department of Agriculture to make "male-only" strains of the New World screwworm (Cochliomyia hominivorax).

"The New World screwworm is a devastating pest of livestock that was eradicated from North and Central America by releasing sterilized male and female flies," Scott says. However, a male-only strain offers several advantages, including potentially more efficient population suppression for the ongoing program. "Efficient genetic control systems have the potential to help eradicate some of the biggest problem pests across the globe," he said.


'/>"/>

Contact: Dr. Max Scott
max_scott@ncsu.edu
919-515-0275
North Carolina State University
Source:Eurekalert

Related biology news :

1. Portable brain-mapping device allows UT Arlington researchers to see where memory fails
2. NJIT researchers probe links between vision problems and cognition in a pioneering study
3. Top Monash researchers recognised with NHMRC Excellence Awards
4. No link found between soy food and endometrial cancer risk, say researchers
5. Researchers use virus to reveal nanopore physics
6. Researchers identify regulation process of protein linked to bipolar disorder
7. Researchers develop free online database for soybean studies
8. NYU and UCSF researchers develop a framework for monitoring oral cancer
9. LSTM researchers identify the complex mechanisms controlling changes in snake venom
10. CU researchers explain mechanism that helps viruses spread
11. UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. (NASDAQ: ... announces the filing of its 2016 Annual Report on Form 10-K ... Commission. ... 10-K is available in the Investor Relations section of the Company,s ... the SEC,s website at http://www.sec.gov . 2016 Year ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... (PRWEB) , ... June 22, 2017 , ... The first ... took 20 years until the first data on cross-contamination of human cell lines with ... been an increasing issue in cell culture labs and is associated with dramatic consequences ...
(Date:6/20/2017)... ... 20, 2017 , ... HorizonScan is providing food and ingredient ... likely threat to their products at the annual IFT conference in Las Vegas, ... expo attracts over 20,000 attendees representing food science professionals from over 90 countries ...
(Date:6/19/2017)... ... June 19, 2017 , ... ... activities supporting EDETEK’s products including training, implementation, support, and client process and SOP ... role. He has previously held leadership roles for service providers and top-tier pharmaceuticals, ...
(Date:6/16/2017)... ... June 16, 2017 , ... Cambridge ... announced that its Anzo Smart Data Lake® (Anzo SDL) solution was named ... the 2017 Software & Information Industry Association (SIIA) CODiE Awards. , Finalists ...
Breaking Biology Technology: