Navigation Links
Researchers develop genetic control mechanism for major livestock pest
Date:6/19/2014

Researchers from North Carolina State University have developed a technique to control populations of the Australian sheep blowfly a major livestock pest in Australia and New Zealand by making female flies dependent upon a common antibiotic to survive.

Dr. Max Scott, professor of entomology at NC State, and his research team genetically modified lines of female Australian sheep blowflies (Lucilia cuprina) so that they required doses of tetracycline in order to live. Female blowflies that did not receive the antibiotic died in the late larval or pupal stages, before reaching adulthood. Several genetically modified lines lacking tetracycline showed 100 percent female deaths.

Scott says that the gene construct responsible for lethality in antibiotic-free diets is female-specific. Interestingly and unexpectedly, the genetically modified female larvae containing the tetracycline lethality genes also took on a crimson color due to overexpression of the linked red fluorescent protein "marker gene." This allows scientists to tell which larvae will be females and which will be males.

"Overexpression of the gene responsible for the reliance on tetracycline also seems to overexpress this marker gene," Scott says.

Since the females will die when not provided tetracycline in their diets, the males can be separated out in the larval stage. This is essential for a "male-only" genetic control program to reduce blowfly populations, Scott says, as fertile males would pass the lethality construct on to female offspring, which would die in the absence of tetracycline. Male larval offspring, however, would still be dangerous to livestock.

In the study, the researchers showed that the tetracycline gene construct also works in Drosophila, the fruit fly "lab rat" of the insect world that is a distant cousin of the sheep blowfly. This holds promise that the genetic system will function in the New World and Old World screwworm, two major livestock pests that are close relatives of the sheep blowfly. Scott is working with the U.S. Department of Agriculture to make "male-only" strains of the New World screwworm (Cochliomyia hominivorax).

"The New World screwworm is a devastating pest of livestock that was eradicated from North and Central America by releasing sterilized male and female flies," Scott says. However, a male-only strain offers several advantages, including potentially more efficient population suppression for the ongoing program. "Efficient genetic control systems have the potential to help eradicate some of the biggest problem pests across the globe," he said.


'/>"/>

Contact: Dr. Max Scott
max_scott@ncsu.edu
919-515-0275
North Carolina State University
Source:Eurekalert

Related biology news :

1. Portable brain-mapping device allows UT Arlington researchers to see where memory fails
2. NJIT researchers probe links between vision problems and cognition in a pioneering study
3. Top Monash researchers recognised with NHMRC Excellence Awards
4. No link found between soy food and endometrial cancer risk, say researchers
5. Researchers use virus to reveal nanopore physics
6. Researchers identify regulation process of protein linked to bipolar disorder
7. Researchers develop free online database for soybean studies
8. NYU and UCSF researchers develop a framework for monitoring oral cancer
9. LSTM researchers identify the complex mechanisms controlling changes in snake venom
10. CU researchers explain mechanism that helps viruses spread
11. UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/6/2016)... 6, 2016 Securus Technologies, a leading ... for public safety, investigation, corrections and monitoring, and ... a five (5) year funding commitment by Securus ... the rehabilitation and reentry support to more inmates ... in 2004, the Prison Entrepreneurship Program (PEP) is ...
(Date:12/2/2016)... , December 1, 2016 ... type (Fingerprint, Voice), Future Technology (Iris Recognition System), ... Region - Global Forecast to 2021", published by ... 442.7 Million in 2016, and is projected to ... a CAGR of 14.06%.      (Logo: ...
(Date:11/30/2016)... , Nov. 30, 2016 Not many of us realize that we ... of recovery so we need to do it well. Inadequate sleep levels have been ... blood pressure, stroke, diabetes, and even cancer. Maybe now is the best ... that could help them to manage their sleep quality? ... ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... ... December 08, 2016 , ... ... for their exceptionally efficient human mesenchymal stem/stromal cell (hMSC) expansion medium. ... media products engineered to radically streamline culture processes, minimize processing time, significantly ...
(Date:12/8/2016)... TAMPA, Fla. , Dec. 8, 2016 /PRNewswire/ ... biopharmaceutical company that discovers, develops and plans to ... today that its shares of common stock were approved ... stock will begin trading on the OTCQX, effective ... To qualify for the OTCQX market, companies must ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... I/II dose escalation and expansion clinical trial for its lead drug candidate, AC0010, ... purpose of the trial was to determine the safety, antitumor activity, and recommended ...
(Date:12/7/2016)... /PRNewswire/ - Zenith Capital Corp. ("Zenith" or the "Company") announces webcast ... the Company,s Annual and Special Meeting. The ... on Thursday, December 15, 2016 at Mount Royal ... 4825 Mount Royal Gate SW, Calgary, Alberta ... and management information circular, containing the matters to be considered ...
Breaking Biology Technology: