Navigation Links
Researchers develop gene therapy that could correct a common form of blindness
Date:1/23/2012

A new gene therapy method developed by University of Florida researchers has the potential to treat a common form of blindness that strikes both youngsters and adults. The technique works by replacing a malfunctioning gene in the eye with a normal working copy that supplies a protein necessary for light-sensitive cells in the eye to function. The findings are published today (Monday, Jan. 23) in the Proceedings of the National Academy of Sciences online.

Several complex and costly steps remain before the gene therapy technique can be used in humans, but once at that stage, it has great potential to change lives.

"Imagine that you can't see or can just barely see, and that could be changed to function at some levels so that you could read, navigate, maybe even drive it would change your life considerably," said study co-author William W. Hauswirth, Ph.D., the Rybaczki-Bullard professor of ophthalmology in the UF College of Medicine and a professor and eminent scholar in department of molecular genetics and microbiology and the UF Genetics Institute. "Providing the gene that's missing is one of the ultimate ways of treating disease and restoring significant visual function."

The researchers tackled a condition called X-linked retinitis pigmentosa, a genetic defect that is passed from mothers to sons. Girls carry the trait, but do not have the kind of vision loss seen among boys. About 100,000 people in the U.S. have a form of retinitis pigmentosa, which is characterized by initial loss of peripheral vision and night vision, which eventually progresses to tunnel vision, then blindness. In some cases, loss of sight coincides with the appearance of dark-colored areas on the usually orange-colored retina.

The UF researchers previously had success pioneering the use of gene therapy in clinical trials to reverse a form of blindness known as Leber's congenital amaurosis. About 5 percent of people who have retinitis pigmentosa
'/>"/>

Contact: Czerne M. Reid
czerne@ufl.edu
352-273-5814
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers meet to refine carbon budget for US East Coast
2. Penn researchers help solve questions about Ethiopians high-altitude adaptations
3. Notre Dame researchers report fundamental malaria discovery
4. Researchers find gene critical to sense of smell in fruit fly
5. Native forest birds in unprecedented trouble, according to University of Hawaii at Manoa researchers
6. Researchers discover green pesticide for citrus pests
7. 2-timing and hybrids: RUB researchers look back on 100 million years of evolution
8. Researchers identify possible receptor for key breast cancer regulator
9. UH Manoa researchers discover novel chemical route to form organic molecules
10. Researchers: Honeybee deaths linked to seed insecticide exposure
11. Worm seeks worm: Caltech researchers find chemical cues driving aggregation in nematodes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... , Dec. 18, 2014   LaunchKey , the ... the post-password and Internet of Things era, today announced ... The venture round was led by Metamorphic Ventures with ... Venture Partners, VegasTechFund, and others.  LaunchKey has raised $4 ...
(Date:12/17/2014)... 16, 2014 Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ... Chemical Sensor Market 2015-2019" report to their offering. ... One major trend upcoming in this market is the ... sensors help in recording of patient data for quick ...
(Date:12/11/2014)... SALEM, N.C. , Dec. 10, 2014  That blood pressure ... quite a while. Hypertension – the medical term for high ... the early 1800s, and the inflatable cuff that,s used in ... doesn,t, however, mean there,s nothing new about hypertension, its triggers ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... new bacterium in an immune-compromised patient, according to a ... belongs to the family Acetobacteraceae and includes bacteria common ... industry, such as vinegar-making. "This is the first ... of the Acetobacteraceae," according to the article. ...
... single atom from the molecular structure of vancomycin aglycon, ... cell wall synthesis, significantly increasing the drug's spectrum of ... common strains of enterococci have become resistant to vancomycin ... This re-engineering effort could help make the drug more ...
... flu is bad enough for healthy people, but the ... weakened immune systems, such as patients on chemotherapy. A ... of Philadelphia will support research to determine how adults ... vulnerable to influenza, and will seek better ways to ...
Cached Biology News:Soil-bound prions that cause CWD remain infectious 2Scientists re-engineer a well-known antibiotic to counter drug resistance 2How can we protect patients with weakened immune systems from influenza? 2How can we protect patients with weakened immune systems from influenza? 3
(Date:1/22/2015)... 22, 2015  Derma Sciences, Inc. (Nasdaq: ... advanced wound care, announces that AMNIOEXCEL® and AMNIOMATRIX®, ... added to the Premier, Inc. Regenerative Skin Grafting ... the AMNIOEXCEL® and AMNIOMATRIX® product lines, which continue ...
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 PlasmaTech Biopharmaceuticals, ... in critical areas, announced the closing of an underwritten public ... purchase up to an aggregate 3,500,000 shares of common stock, ... per warrant.  The warrants have a per share exercise price ...
(Date:12/24/2014)... 23, 2014 “Preparative & Process ... Flash), Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), ... Agriculture) - Forecasts to 2019” provides a detailed ... current market trends, and strategies impacting the preparative ...
(Date:12/24/2014)... December 23, 2014 SoundConnect’s ... to introduce cutting edge communication technology, provide continued ... upgrades. This webinar series demonstrates online communication features ... leverage web conferencing’s most innovative and powerful tools. ...
Breaking Biology Technology:Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
...   Hospitals, health systems to benefit,from ... and other,performance management solutions Elsevier ... products,and services, has struck an exclusive partnership with ... learning solutions for process,improvement. Elsevier will market ...
... carbon, has the potential to make consumer electronic devices ... shrinking scale of electronics, also make graphene difficult to ... In September 2010, a UCLA research team ... and were able to fabricate graphene transistors with unparalleled ...
... 2011 Pharmacyclics, Inc. (Nasdaq: PCYC ) ... agreements with various institutional investors and its CEO for ... in a registered direct offering at $8.85 per share, ... of the offering, before deducting expenses, are expected to ...
Cached Biology Technology:Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 2Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 3Elsevier Strikes Exclusive eLearning Partnership with The Quality Group 4UCLA team reports scalable fabrication of self-aligned graphene transistors, circuits 2Pharmacyclics Announces Results of Registered Direct Offering 2Pharmacyclics Announces Results of Registered Direct Offering 3
... provides a genome-wide microRNA (miRNA) expression profiling ... design, which enable highly sensitive and specific ... standard arrays for mature miRNA of all ... the Sanger miRBase database (Release 8.2). Our ...
... Microarrays designed for immunological studies, vaccine ... the flexible and powerful Paraflo microfluidic ... available as part of our comprehensive ... Custom Probe Content Probe content ...
... Custom peptide microarrays designed for ... serum samples and built on the ... platform. Thousands of customer specified sequences ... Sciences can provide assistance with custom ...
... the first time, you can identify and ... efficiently without interferences. The Agilent Multiple Affinity ... multiple high-abundant proteins from human serum, plasma, ... one device. With this revolutionary system, you ...
Biology Products: