Navigation Links
Researchers develop MRSA-killing paint
Date:8/16/2010

he American Chemical Society.

Dordick said the nanotube-enzyme coating builds on several years of previous work embedding enzymes into polymers. In previous studies, Dordick and Kane discovered that enzymes attached to carbon nanotubes were more stable and more densely packed when embedded into polymers than enzymes alone.

"If we put an enzyme directly in a coating (such as paint) it will slowly pop out," Kane said. "We wanted to create a stabilizing environment, and the nanotubes allow us to do that."

Having established the basics of embedding enzymes into polymers, they turned their attention to practical applications.

"We asked ourselves were there examples in nature where enzymes can be exploited that have activity against bacteria?" Dordick said. The answer was yes and the team quickly focused on lysostaphin, an enzyme secreted by non-pathogenic Staph strains, harmless to humans and other organisms, capable of killing Staphylococcus aureus, including MRSA, and commercially available.

"It's very effective. If you put a tiny amount of lysostaphin in a solution with Staphylococcus aureus, you'll see the bacteria die almost immediately," Kane said.

Lysostaphin works by first attaching itself to the bacterial cell wall and then slicing open the cell wall (the enzyme's name derives from the Greek "lysis" meaning "to loosen or release").

"Lysostaphin is exceptionally selective," Dordick said. "It doesn't work against other bacteria and it is not toxic to human cells."

The enzyme is attached to the carbon nanotube with a short flexible polymer link, which improves its ability to reach the MRSA bacteria, said Kane.

"The more the lysostaphin is able to move around, the more it is able to function." Dordick said.

They successfully tested the resulting nanotube-enzyme conjugate at Albany Medical College, where Metzger maintains strains of MRSA.

"At the en
'/>"/>

Contact: Mary Martialay
martim12@rpi.edu
518-276-2146
Rensselaer Polytechnic Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers discover genetic link between immune system, Parkinsons disease
2. Ben-Gurion U. researchers receive US-AID MERC grant for water project with the Palestinian authority
3. Illinois researchers use pyrosequencing to study canine intestinal bacteria
4. Researchers find that one type of stem cell creates a niche for another type in bone marrow
5. VIB and UGent researchers identify key mechanisms of cell division in plants
6. Rutgers researchers assess severity of prostate cancers using magnetic resonance imaging
7. Carnegie Mellon researchers turn up brightness on fluorescent probes
8. Researchers demonstrate highly directional terahertz laser rays
9. Hebrew University researchers identify gene related to chronic pain
10. UC Riverside researchers measure diesel emissions on the freeway
11. Windy cities: Researchers invent new tool to calculate hurricane risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/12/2014)... come under attack from a pathogen, they sometimes respond ... the attack, committing "cell suicide" to thwart further damage ... small, often microscopic, spots or lesions on the plant. ... understand how the plant regulates this "spotty" defense mechanism ... Researchers at North Carolina State University have identified a ...
(Date:9/12/2014)... and POINT ROBERTS, Washington , September 12, ... http://www.investorideas.com ) a global news source covering leading sectors including ... on the September 9 th launch of Apple Pay, ... Intelligence, Janice Kephart , founder of the Secure Identity ... of NXT-ID, Inc, (NASDAQ: NXTD ) a company ...
(Date:9/11/2014)... Amsterdam, NL, 11 September 2014 Patients with ... preparation and ingestion, which could contribute to poor ... Published studies have also suggested that PD is ... control groups. A report published in the ... in patients with mild-to-moderate PD, finding that the ...
Breaking Biology News(10 mins):Corn spots: Study finds important genes in defense response 2Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 2Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 3Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 4Biometric Experts Comment on Launch of Apple Pay Smart Wallet Payment Service 5Few mild-to-moderate Parkinson's disease patients suffer from malnutrition, yet almost one-third are at risk 2
... Study of Hepatitis C (PEDS-C) trial reveals that children ... display significant changes in height, weight, body mass index ... issue of Hepatology , a journal of the ... that most growth-related side effects are reversible with cessation ...
... New Rochelle, NY, August 9, 2012Despite criticism from Congressional ... its Rim of the Pacific (RIMPAC) 2012 international maritime ... 50% biofuels blend. The Navy contends that renewable energy ... play in enhancing national security and energy independence. Tom ...
... University researchers are teaming up with Coastal Carolina University ... along the Savannah River to gather data for the ... and transmit real-time information about the quality and quantity ... project leaders Gene Eidson, director of Clemson,s Institute of ...
Cached Biology News:Height, weight and BMI changes seen in children treated with peginterferon alpha for hepatitis C 2US Navy defends renewable fuels strategy in Industrial Biotechnology Journal 2Clemson, Coastal Carolina universities to set hundreds of sensors in Savannah River 2
(Date:9/12/2014)... an electric field (magnetoelectric memory [MEM] effect), can ... for information processing and storage. Multiferroic materials are ... the coexistence of electric and magnetic orders. On ... and magnetic polarizations is rare in known materials, ... effect. This article briefly reviews a new family ...
(Date:9/12/2014)... Advancing the front lines of ... and biological threats is the mission of an ... (WPI) and the Georgian National Academy of Sciences, ... and Security Programme of the North Atlantic Treaty ... Workshop series, the event is titled “Nanotechnology to ...
(Date:9/12/2014)... (PRWEB) September 12, 2014 Today, “The ... on Indiegogo. , The film, directed by former ... Aldrin, Shimon Peres, Ashton Kutcher, Will.i.Am, Michio Kaku, and ... and there’s only one university in the world devoted ... change the lives of a billion people: Singularity University. ...
(Date:9/12/2014)... NM (PRWEB) September 12, 2014 Sandia ... an exclusive option agreement with STC.UNM (STC) for a ... Mexico (UNM) in Albuquerque, New Mexico, and Queen Mary ... of technologies, called the Recombinant Fluorescent Antibody Technology Platform ... Department of Internal Medicine and Dr. Angray Kang from ...
Breaking Biology Technology:Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 2Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 3Sandia Biotech and STC.UNM Announce Option Agreement to License Novel Recombinant Antibody Technology 4
... Enanta Pharmaceuticals, Inc. announced today that its lead ... inhibitor program, EDP-239, has been recognized on Windhover,s list ... to Watch." EDP-239 was chosen by independent experts at ... a clinically-validated target, is a non-structural viral protein that ...
... at deCODE Genetics and academic collaborators from Iceland, The Netherlands, ... today report the discovery of a variant in the sequence ... cell carcinoma of the skin (BCC), as well as prostate ...  The study was done in collaboration with Illumina, Inc., and ...
... Sept. 23, 2011 Citizens Bank today announced that ... a major expansion by The Wistar Institute that includes ... historic facility at 36th and Spruce streets in University ... an international leader in basic biomedical research, particularly cancer ...
Cached Biology Technology:Enanta's Lead NS5A Inhibitor Candidate for HCV, EDP-239, Selected as One of Windhover's Top 10 Infectious Disease Projects to Watch 2Enanta's Lead NS5A Inhibitor Candidate for HCV, EDP-239, Selected as One of Windhover's Top 10 Infectious Disease Projects to Watch 3deCODE genetics, Together with Academic Collaborators and Illumina, Discovers Genetic Risk Factor for Skin, Prostate and Brain Cancers 2deCODE genetics, Together with Academic Collaborators and Illumina, Discovers Genetic Risk Factor for Skin, Prostate and Brain Cancers 3Citizens Bank Provides $70 Million in Financing Toward $100 Million Expansion of The Wistar Institute 2
... Description: ,Kit containing Dermal Fibroblasts ... supplied as a long-term culture, and is ... of continuous growth from the date supplied, ... ,Source: Dermis, mouse/BalbC, embryonic day 18.5 ...
... Protein G bind specifically to Fc regions ... Protein G conjugates are commonly used as ... immunoglobulin subtypes from serum, hybridoma ascites fluids, ... These reagents are also commonly used to ...
... SigmaStat 3.5 is a user-friendly statistical software ... them to perform statistical analysis without being ... about your data and research and SigmaStat ... data against the tests underlying assumptions and ...
... SOS Protein Solubility Service, We ... , New SOS technology yields the best ... parameters applied on each clone submitted , ... ,The new protein Solubility Optimization Service ...
Biology Products: