Navigation Links
Researchers create vaccine for dust-mite allergies
Date:7/22/2014

the body's natural inclination to defend itself against foreign bodies. A key to the formula lies in the use of an adjuvantwhich boosts the potency of the vaccinecalled CpG. The booster has been used successfully in cancer vaccines but never had been tested as a vaccine for dust-mite allergies. Put broadly, CpG sets off a fire alarm within the body, springing immune cells into action. Those immune cells absorb the CpG and dispose of it.

This is important, because as the immune cells absorb CpG, they're also taking in the vaccine, which has been added to the package, much like your mother may have wrapped a bitter pill around something tasty to get you to swallow it. In another twist, combining the antigen (the vaccine) and CpG causes the body to change its immune response, producing antibodies that dampen the damaging health effects dust-mite allergens generally cause.

In lab tests, the CpG-antigen package, at 300 nanometers in size, was absorbed 90 percent of the time by immune cells, the UI-led team reports. The researchers followed up those experiments by giving the package to mice and exposing the animals to dust-mite allergens every other day for nine days total. In analyses conducted at the UI College of Public Health, packages with CpG yielded greater production of the desirable antibodies, while lung inflammation was lower than particles that did not contain CpG, the researchers report.

"This is exactly what we were hoping for," says Salem, whose primary appointment is in the College of Pharmacy.

The researchers will continue to test the vaccine in the hope that it can eventually be used to treat patients.


'/>"/>

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
4. UNH researchers find African farmers need better climate change data to improve farming practices
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. Researchers print live cells with a standard inkjet printer
8. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
9. Researchers reveal how a single gene mutation leads to uncontrolled obesity
10. Researchers discover novel therapy for Crohns disease
11. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers create vaccine for dust-mite allergies
(Date:6/1/2015)... According to a new market research report ... & Touchless), Application (Consumer Electronics, Automotive, & Others), Product ... Forecast to 2020", published by MarketsandMarkets, the Gesture Recognition ... Billion by 2020, at a CAGR of 28.23% between ... data T ables and   86   F ...
(Date:6/1/2015)... 1, 2015 According to ... Market by Application (Government, Military & Defense, Healthcare, ... and Security), Technology (Face Recognition, Fingerprint Recognition, Iris ... Recognition, and Others), Function (Contact and Non-Contact) & ... Europe , APAC, Row) - Global ...
(Date:5/29/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/2w6zgs/facial ... "Facial Recognition Market by Solution, by Software, by ... 2020" report to their offering. ... technology become more efficient and cost effective. This ... investment from the commercial sector. The development of ...
Breaking Biology News(10 mins):Gesture Recognition & Touchless Sensing Market Worth $23.55 Billion by 2020 2Gesture Recognition & Touchless Sensing Market Worth $23.55 Billion by 2020 3Gesture Recognition & Touchless Sensing Market Worth $23.55 Billion by 2020 4Next Generation Biometrics Market Worth $24,448.84 Million by 2020 2Next Generation Biometrics Market Worth $24,448.84 Million by 2020 3Next Generation Biometrics Market Worth $24,448.84 Million by 2020 4Global advanced Facial Recognition Market Expected to Grow From $2.77 Billion in 2015 to $6.19 Billion in 2020, at an Estimated CAGR of 17.4% 2
... with a common condition that causes frequent nighttime ... minimally invasive treatment that shrinks the prostate, suggests a ... 38th Annual Scientific Meeting in New Orleans. The early ... prostatic artery embolization (PAE), which reduces blood flow to ...
... Inc. (OTC Markets: MDBX) ( www.medboxinc.com ), a leader ... to various medical and retail related industries worldwide, seeks ... in the mushrooming legal marijuana industry and has issued a ... past, present, and future projects. Company CEO, ...
... sea levels, new research indicates that cutting emissions of ... this century. The research team found that reductions ... atmosphere could temporarily forestall the rate of sea level ... avoid potentially dangerous sea level rise, we could cut ...
Cached Biology News:Nonsurgical treatment turns back the clock, shrinks enlarged prostate 2Medbox Positions Itself as the Leader on Wall Street in the Legalized Marijuana Industry 2Medbox Positions Itself as the Leader on Wall Street in the Legalized Marijuana Industry 3Medbox Positions Itself as the Leader on Wall Street in the Legalized Marijuana Industry 4Medbox Positions Itself as the Leader on Wall Street in the Legalized Marijuana Industry 5Cutting specific pollutants would slow sea level rise 2Cutting specific pollutants would slow sea level rise 3
(Date:6/2/2015)... Mass. , June 2, 2015  Alere ... in rapid diagnostics, joined the White House Antibiotic ... of commitments to support and advance the President,s ... Company,s commitments include a number of measurable goals ... when achieved, will help healthcare providers protect their ...
(Date:6/2/2015)... June 02, 2015 Through rare discovery ... Yancy Corporation is enabling World Scientists to ... and biological sample, displaying the full nature (position, shape, ... atoms. , Jeff Porter, Co-Founder of the Yancy Corporation, ... that – rare. They come once in a lifetime, ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 German-based Moenninghoff ... United States distributor for the Moenninghoff product line ... “I am pleased to announce that the R.M. Hoffman ... For our firm, founded in 1916, this is a ... Hoffman is the kind of professional distributor we need ...
(Date:6/1/2015)... 2015 Chosen for his engaging ... Uldrich has been selected as keynote speaker for ... He will deliver his keynote: "Don't Stop Thinking ... presentations to the American Medical Association, Blue Cross ... Alcetel-Lucent/Verizon Forum on Wireless Healthcare, United Healthcare, IASIS ...
Breaking Biology Technology:Alere Announces Broad Initiatives to Help Combat Antibiotic Resistance during White House Antibiotic Stewardship Forum 2Scientists Eying Rare Discovery Of New Physics & Light Microscope Technology 2R.M. Hoffman Company designated official United States distributor for the Moenninghoff product line. 2R.M. Hoffman Company designated official United States distributor for the Moenninghoff product line. 3Futurist Jack Uldrich to Address the Future of Pharmaceuticals 2
... Live On Company,s Website -, TUSTIN, Calif., Oct. ... clinical stage biopharmaceutical,company developing monoclonal antibodies for the treatment ... management will,present at the BIO Investor Forum 2008 on ... EDT). The conference will be held at the Palace ...
... 28 Neurocrine Biosciences,(Nasdaq: NBIX ) announces the following Webcast:, ... When: October 28, 2008 @ 5 p.m. Eastern ... How: Live over the Internet -- Simply log ... above., Contact: Claudia Woodworth, 858-617-7759 ...
... MEMY ) today announced that it has received,notice ... of the,Company,s common stock will be transferred from The ... the opening of trading on October,28, 2008. The Company,s ... The Panel has also notified the Company that it ...
Cached Biology Technology:Peregrine Pharmaceuticals to Present at BIO Investor Forum 2008 2Memory Pharmaceuticals Provides Update on NASDAQ Listing Status 2Memory Pharmaceuticals Provides Update on NASDAQ Listing Status 3
Anti-Human Factor XI Purified (Polyclonal) (sheep IgG)...
...
This antibody detects an ~25 kDa band, corresponding to the expected molecular mass of Rab3A, on immunoblots. The antibody specificity is confirmed in peptide inhibition immunoblotting studies....
HLA II DG+DR+DP Monoclonal Antibody, Purified, Unconjugated, Clone: IQU9 This antibody is specific for the monomorphic determinant of the HLA Class II beta chains of the human MHC (28 kDa)....
Biology Products: