Navigation Links
Researchers combine active proteins with material derived from fruit fly
Date:4/20/2011

a strand of a spider's web, Bondos said.

"It clued us in that this was making materials," said Matthews, Rice's Stewart Memorial Professor of Biochemistry and Cell Biology and former dean of the Wiess School of Natural Sciences.

The chance discovery prompted a 2009 paper in the journal Biomacromolecules about the material they dubbed "ultrax," a superstrong and highly elastic natural fiber.

"We found that if you put a little drop of this protein solution on a slide, the Ubx forms a film. And if you touch a needle to that film, you can draw a fiber," Matthews said. "Then we asked, What if we could incorporate other functions into these materials? Can we make chimeras?" The answer was yes, though it took ingenuity to prove.

Chimeras in the biological world contain genetically distinct cells from two or more sources. In Greek mythology, chimeras are beings with parts from multiple animals; a pig with wings, for instance, would qualify. But real chimeras are usually more subtle. On the molecular level, chimeras are proteins that are fused into a single polypeptide and can be purified as a single molecular entity.

As a proof of principle, the team used gene-fusion techniques to create chimeras by combining Ubx with fluorescent and luminescent proteins to see if they remained functional. They did. The combined materials still formed a film on water. Drawn into fibers and put under a microscope, Ubx combined with enhanced green fluorescent protein (EGFP) kept its bright green color. Ubx-mCherry was bright red, the brown protein myoglobin (from sperm whales) was brown, and luciferase glowed.

Huang was able to make patterns with strands generated by the chimeras by twisting red and green fluorescent proteins into candy cane-like tubes, or lacing them on a frame. "This patterning technique is pretty unique and very simple," said Huang, who recently defended his thesis on the subject. He said making solid materials with fu
'/>"/>

Contact: David Ruth
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... July 29, 2014 Research and Markets ... Business Intelligence (BI) Market 2014-2018" report to their ... The term BI refers to applications and ... or analyzing information about a company,s operations. BI help ... their business; for example, metrics on sales, production, and ...
(Date:7/29/2014)... of a stroke is an immensely complex challenge ... as effective therapy. Advancing such knowledge to improve ... focus of research by Sergei Adamovich, associate professor ... faculty more than a decade ago. It is ... from sources such as the National Institutes of ...
(Date:7/29/2014)... YORK , July 29, 2014  When it comes to ... new devices, if not the last. However, when it comes to ... Though the market for the Internet of Things and its ... make an impact in the healthcare industry, whether it,s in the ... to keep us fit. With that in mind, InformationWeek ...
Breaking Biology News(10 mins):Global SaaS-based Business Intelligence (BI) Market 2014-2018 2Continuing the quest for better stroke therapies 2Continuing the quest for better stroke therapies 3
... 2013Dr. Carissa Klein of Australia was awarded the APEC ... by John Wiley & Sons, Inc., and Elsevier, on ... Research and Technology. Dr. Klein,s selection is ... Queensland that uniquely addresses the issue of sustainable ocean ...
... The strain of cholera that has sickened thousands in Haiti ... to the island over the past three years as some ... mBio , the online open-access journal of the American Society ... are consistent with earlier findings that indicate Vibrio cholerae ...
... TEMPE, Ariz -- Knowing virtually everything about how the ... for instance, precisely how particular cells develop into ... in understanding the basics of what drives biological processes. ... advances in medical science, bioengineering and related areas. ...
Cached Biology News:ASPIRE prize winner balances ocean conservation and socioeconomic viability 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 3Biomedical research revealing secrets of cell behavior 2
(Date:7/29/2014)... , July 29, 2014  Discovery Laboratories, Inc. ... advancing a new standard of respiratory critical care, will ... August 5, 2014 before the open of the ... will host a live teleconference and webcast at ... conference call, Discovery Labs, management will discuss the ...
(Date:7/29/2014)... , July 29, 2014  ImmunoClin Corporation (IMCL) ... medicine, treatment of infectious diseases as well as ... and prevention of pathologies like cardiovascular disease, Alzheimer,s ... 2014, ImmunoClin Corporation will complete the strategic relocation ... D.C. , a key center of North ...
(Date:7/29/2014)... 2014 Genera Energy Inc. ... innovation and supply chain advancements, has announced the ... Energy Grange™ and Supply ASSURE™. Both systems ... testing aimed at consolidating and simplifying the entire ... farmers and feedstock end users. , “Through the ...
(Date:7/29/2014)... July 29, 2014  United Therapeutics Corporation (NASDAQ: ... financial results for the second quarter ended ... shows that our medicines are reaching increasing ... hypertension (PAH)," said Martine Rothblatt, Ph.D., United ... commercial launch this quarter of our extended-release ...
Breaking Biology Technology:Discovery Labs to Report 2014 Second Quarter Financial Results and Hold Conference Call on Tuesday, August 5, 2014 at 9:00 a.m. Eastern Time 2ImmunoClin Corporation (IMCL) Relocates Corporate Headquarters to Washington, DC 2ImmunoClin Corporation (IMCL) Relocates Corporate Headquarters to Washington, DC 3Genera Energy Introduces Proprietary Feedstock Management Systems 2Genera Energy Introduces Proprietary Feedstock Management Systems 3Genera Energy Introduces Proprietary Feedstock Management Systems 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 2United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 5United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 6United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 7United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 8United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 9United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 10United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 11United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 12United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 13
...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... Neurocrine Biosciences, will be presenting at the 24th Annual Roth ... takes place on Tuesday, March 13 at 2:00 p.m. Pacific ... webcast and may be accessed on the Company,s website at ...
... ATLANTA, March 7, 2012 Harriet L. Robinson, Ph.D., ... a biotech company specializing in the development of HIV/AIDS ... scientists may be one step closer to a vaccine ... study results were unveiled by Dr. Robinson during a ...
... BETHESDA, Md., March 7, 2012   Spherix Incorporated ... innovator in biotechnology for therapy in diabetes, metabolic ... regulatory consulting services to food, supplement, biotechnology and ... its drug candidates, SPX-106T, arrested development and reduced ...
Cached Biology Technology:GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 2GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 3GeoVax Labs Presents New Findings on Potential HIV Vaccine at 2012 Conference on Retroviruses and Opportunistic Infections (CROI) 4SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 2SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 3SPX-106T Arrests Development of Atherosclerotic Plaques in Mouse Model of Cardiovascular Disease 4
Request Info...
Prepared in distilled water....
... white. The extinction coefficient , E(1%) at ... phosphate-buffered saline, pH 7.4, containing ... 50% glycerol. Avidin (from egg white) is conjugated ... molecular sieving and is completely ...
NM522 contains an F episome, which is required for production of ssDNA and for blue/white color selection. To maintain the F, NM522 should be grown on minimal (M-9) medium....
Biology Products: