Navigation Links
Researchers coat titanium with polymer to improve integration of joint replacements
Date:7/1/2008

Research at the Georgia Institute of Technology shows that coating a titanium implant with a new biologically inspired material enhances tissue healing, improves bone growth around the implant and strengthens the attachment and integration of the implant to the bone.

"We designed a coating that specifically communicates with cells and we're telling the cells to grow bone around the implant," said Andrs Garca, professor and Woodruff Faculty Fellow in Georgia Tech's Woodruff School of Mechanical Engineering and the Petit Institute for Bioengineering and Bioscience.

Details of the new coating appear in the July issue of the journal Biomaterials. The research was supported by the National Institutes of Health, the Arthritis Foundation and the Georgia Tech/Emory National Science Foundation Engineering Research Center on the Engineering of Living Tissues.

Total knee and hip replacements typically last about 15 years until the components wear down or loosen. For many younger patients, this means a second surgery to replace the first artificial joint. With approximately 40 percent of the 712,000 total hip and knee replacements in the United States in 2004 performed on younger patients 45-64 years old, improving the lifetime of the titanium joints and creating a better connection with the bone becomes extremely important.

Current clinical practice includes roughening the surface of the titanium implant or coating it with a flaky, hard-to-apply ceramic that bonds directly to bone.

In collaboration with Georgia Tech School of Chemistry and Biochemistry professor David Collard, graduate students Tim Petrie and Jenny Raynor, and research technician Kellie Burns, Garca coated the titanium with a thin, dense polymer.

"Our coating consists of a high density of polymer strands, akin to the bristles on a toothbrush, that we can then modify to present our bio-inspired, bioactive protein," explained Garca.'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers link early stem cell mutation to autism
2. Montreal Heart Institute and Mount Sinai Hospital researchers contribute to Crohns disease study
3. Salk researchers reprogram adult stem cells in their natural environment
4. UIC researchers make promising finding in severe lung disease
5. Montana State researchers release guide to noninvasive carnivore research
6. Growth hormones link to starvation may be clue to increasing life span, researchers find
7. Researchers explain nitrogen paradox in forests
8. UNH researchers test sediment-scrubbing technology in NH river
9. Florida researchers receive JDRF Excellence in Clinical Research Award
10. LIAI researchers discover new cellular mechanism that will significantly advance vaccine development
11. Stem cell researchers give old muscle new pep
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers coat titanium with polymer to improve integration of joint replacements
(Date:10/15/2014)... virus is spreading rapidly and to an unexpected extent. ... the past and the virus shows a new disease ... before. For this reason, the German National Academy of ... and Engineering, and the Union of the German Academies ... the Ebola epidemic today. , In the statement the ...
(Date:10/14/2014)... Like discriminating thieves, prostate cancer tumors scavenge and hoard ... But such avarice may be a fatal weakness. ... to kill prostate cancer cells by delivering a trove ... the diseased cells brimming with the mineral, leaving non-cancer ... drugs already commercially available for other uses, could soon ...
(Date:10/14/2014)... research team has discovered a new kind of stem cell ... that lines liver blood vessels, according to a study published ... existence of such a cell type contradicts current theory on ... may hold clues to origins of, and future treatment for, ... single cell into a complex being made up of more ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Prostate cancer's penchant for copper may be a fatal flaw 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
... scientists at the University of Minnesota Medical School and ... and made suggestions on how to advance research and ... published in the January 2008 issue of the Lancet ... , Many neurological disorders are difficult to treat because ...
... and the National Center for Ecological Analysis and Synthesis ... predict gene flow across landscapes. Their approach could give ... for wildlife corridors, which are crucial to protecting biodiversity. ... theory and ecological connectivity, said Brad McRae, head of ...
... the University of California, San Diego have discovered a ... in the gene are present in both the female ... a paper that appears online today in the journal ... consent mutation because of its unusual properties. Mutations ...
Cached Biology News:International scientists tackle obstacles to treating brain disorders 2International scientists tackle obstacles to treating brain disorders 3Model connects circuit theory to wildlife corridors 2Biologists find unusual plant gene: abstinence by mutual consent 2Biologists find unusual plant gene: abstinence by mutual consent 3
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... defines and segments the bio-based advanced phase change ... of revenue. , Browse through the TOC of ... report to get an idea of the in-depth ... the segmentation in the Asia-Pacific bio-based advanced phase ...
(Date:10/18/2014)... The Asia-Pacific Liquid Crystal on Silicon (LCoS) display ... Asia-Pacific with analysis and forecast of revenue. This market ... expected to reach $380.0 million by 2018, at a ... through the TOC of the Asia-Pacific LCoS display market ... provided. This also provides a glimpse of the segmentation ...
(Date:10/18/2014)... The report " Cloud Analytics Market ... Speech; Machine; Video; Predictive Analytics: Global Advancements, Delivery ... Analysis (2013 - 2018) ", defines and segments ... segments with an in-depth analysis and forecasting of ... driving this market, various restraints, and opportunities impacting ...
(Date:10/17/2014)... Germany , October 17, 2014 ... Translational research in cancer and other diseases will ... American Society of Human Genetics annual meeting   ... to Ingenuity ®  Knowledge Base greatly exceeds any ... Ingenuity ®  Variant Analysis™ adds fully integrated ...
Breaking Biology Technology:The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 4The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 2Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 4Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... , ... , , , , ... 2100 bioanalyzer can,be used in combination with Standardized RT (StaRT)-PCR ... obtain highly reproducible, standardized gene expression,measurement with RT-PCR. The internal ...
... , , ... , , , This Application ... kit can be used to detect cell surface,and intracellular protein targets ... staining on CCRF-CEM cells and intracellular,glucocorticoid receptor (GR) staining of H4 ...
... , ... , , This Application Note describes ... be used to determine the efficiency,of transfection of mammalian cells using ... with,expression vectors encoding GFP from two different sources, and optimization,of transfection ...
Cached Biology Technology:Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 2Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 3Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 4Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 5Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 6Quantitative end-point RT-PCR gene,expression measurement using the,Agilent 2100 Bioanalyzer and,standardized RT-PCR 7Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 2Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 3Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 4Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 5Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 6Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 7Detection of antibody-stained cell,surface and intracellular protein targets,with the Agilent 2100 bioanalyzer 8Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 2Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 3Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 4Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 5Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 6Monitoring transfection efficiency by,green fluorescent protein (GFP) detection,with the Agilent 2100 bioanalyzer 7
... Error-free cloning of BAC (100+kb), fosmid ... Greater insert stability than any othe BAC ... for high yields and easy recombinant DNA ... or transcription-free (pSMART VC) vectors for the ...
Anti-Goat HRP-DAB Cell & Tissue Staining Kit...
CHIMAERIC HUMAN IgA2 ANTI NP...
... Cloning Kit includes the pZErO-2 ... selection in E. coli. The ... to eliminate high background. The ... reagents you need for simple ...
Biology Products: