Navigation Links
Researchers characterize stem cell function
Date:3/11/2010

The promise of stem cells lies in their unique ability to differentiate into a multitude of different types of cells. But in order to determine how to use stem cells for new therapeutics, scientists and engineers need to answer a fundamental question: if a stem cell changes to look like a certain type of cell, how do we know if it will behave like a certain type of cell?

Researchers at Northwestern University's McCormick School of Engineering are the first to fully characterize a special type of stem cell, endothelial progenitor cells (EPCs) that exist in circulating blood, to see if they can behave as endothelial cells in the body when cultured on a bioengineered surface.

The results, published online in the journal Stem Cells show promise for a new generation of tissue-engineered vascular grafts which could improve the success rate of surgery for peripheral arterial disease. Peripheral arterial disease is estimated to affect one in every 20 Americans over the age of 50, a total of 8 to 12 million people.

"Normally, stem cells are not studied in the context of improving vascular grafts for bypass surgery. Therefore, we had to develop new tests to assess their use in this application," says Guillermo Ameer, senior author of the paper and associate professor of biomedical engineering and surgery. "We looked at the function of the cells on a citric acid-based polymer, which will be the basis for a new generation of bioengineered vascular grafts."

In the study, Josephine Allen, then a graduate student in Ameer's lab, and colleagues isolated endothelial progenitor cells from eight tablespoons of blood. In approximately half of the attempts, the team was able to isolate the EPCs to expand to make millions of endothelial cells that can behave like the cells of a blood vessel.

Once the endothelial-like cell colonies were established, the research team performed a battery of tests to examine the properties and funct
'/>"/>

Contact: Kyle Delaney
k-delaney@northwestern.edu
847-467-4010
Northwestern University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Penn researchers identify immune cells that fight parasites may promote allergies and asthma
2. VAI researchers develop tool to help study prostate cancer
3. Researchers examine plants ability to identify, block invading bacteria
4. Community involvement important in fight against childhood obesity, according to UTHealth researchers
5. Exercise counters negative effects of weight regain, researchers find
6. Rice researchers make graphene hybrid
7. New dinosaur rears its head; U-M researchers part of team announcing find
8. Discovery in legumes could reduce fertilizer use, aid environment: Stanford researchers
9. Researchers fishing for cancer cure discover active DHA derivatives
10. Researchers determine how ATP, molecule bearing the fuel of life, is broken down in cells
11. NOAA, NASA and Old Dominion researchers measure impacts of changing climate on ocean biology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... Kina, 31. juli 2015 Den 10. internationale ... af BGI fra den 22. - 25. oktober i ... fejrer sin 10-års fødselsdag i år. Siden starten i ... årlige møder på ,omik,-feltet, og er en af de ... ICG-10 fokuserer på nylige gennembrud og fremskridt inden ...
(Date:7/31/2015)... 2015 BGI llevará a cabo la 10ª Conferencia ... 25 de octubre de 2015, en Shenzhen, ... décimo aniversario este año. Desde su inauguración en 2006, ... anuales más influyentes del mundo en los campos de ... más dinámicas, entusiastas y amenas. ICG-10 se ...
(Date:7/31/2015)... julho de 2015 A 10 a. ... realizada pela BGI de 22-25 de outubro de 2015, em ... A conferência está celebrando seu 10 o. aniversário este ... tornou uma das reuniões mais influentes do mundo no ... dinâmicos, entusiastas e prazerosos. A ICG-10 ...
Breaking Biology News(10 mins):Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3
... become even heavier, resulting in amplification of obesity across ... who found that chemical changes in the ways genes ... affect successive generations of mice. "There is an ... recognized as a worldwide phenomenon," said Dr. Robert A. ...
... by the Centre for Plant Integrative Biology at The University ... unseen side of plant biology the root. Although ... critical to our lives. They provide the crops we eat ... store food. Roots are complex branching organs and show a ...
... who eat nuts or nut products like peanut butter ... asthma by more than 50 percent over women who ... to new research from the Netherlands. "We were ... versus rare nut product consumption during pregnancy and symptoms ...
Cached Biology News:The epigenetics of increasing weight through the generations 2The emerging story of plant roots 2Consumption of nut products during pregnancy linked to increased asthma in children 2
(Date:7/31/2015)... , July 31, 2015 In ... resources that help them drive positive health outcomes, ... vital source of patient care in their communities. ... annual tradeshow and conference, AmerisourceBergen announced a new ... Pharmacy Services Administration Organization and help independent pharmacies ...
(Date:7/31/2015)... Texas (PRWEB) , ... July 31, 2015 , ... ... report, offering competitive market analysis and premium industry insights on the global resorcinol ... based on a collective study of vivid market scenarios and analysis of primary ...
(Date:7/31/2015)... 2015 China Cord Blood Corporation (NYSE: CO) ... leading provider of cord blood collection, laboratory testing, hematopoietic ... announced that the Company has filed its Annual Report ... Commission. The filed Form 20-F includes audited financial statements ... Form 20-F can be accessed by visiting the U.S. ...
(Date:7/31/2015)... , ... July 31, 2015 , ... ... the detection and quantification of partially hydrolyzed gluten in foods, has been accepted ... adopted the method “Partially Hydrolyzed Gluten in Fermented Cereal-Based Products by R5 Competitive ...
Breaking Biology Technology:AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4China Cord Blood Corporation Files Its Annual Report on Form 20-F 2RIDASCREEN® Competitve Gliadin Receives AOAC Official First Action Status 2
... have a penchant for the CSI side of project management ... calls suggesting a spinoff. "CSI: Project Management" has such a ... recently is the flurry of news about Acela, the fast ... the story, cracks have developed in the disc brakes and ...
... some of the same technology used by Internet search engines ... crowded. , ,The University of Wisconsin-Madison E-Business Consortium ... efficiency, security and enterprise readiness in a recently published ... overall winner, ceding ground only in security to ...
... effective and proper networking techniques, you may not be maximizing ... other professionals. While people have their own networking style that ... ,You need to do what works best for you and ... learn new ideas about networking from other professionals who have ...
Cached Biology Technology:When innovation gets off track 2When innovation gets off track 3Improve your networking skills by learning from other professionals 2Improve your networking skills by learning from other professionals 3Improve your networking skills by learning from other professionals 4
C/EBPalpha Antibody Shipping Temperature: Cold Storage Temperature: -20C...
Mouse monoclonal [GB3] to Kalinin ( Abpromise for all tested applications). entrezGeneID: 3918 SwissProtID: Q13753...
Rabbit polyclonal to VEZT ( Abpromise for all tested applications). Antigen: Full length human VEZT conjugated to GST Entrez Gene ID: 55591 Swiss Protein ID: Q9HBM0...
AADAC Immunogen: AADAC (NP_001077, 201 a.a. ~ 301 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Biology Products: