Navigation Links
Researchers characterize biomechanics of ovarian cells according to phenotype at stages of cancer
Date:7/5/2011

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal: Nanomedicine http://www.nanomedjournal.com/article/S1549-9634%2811%2900184-5/abstract

By studying the viscoelastic properties of the ovarian cells of mice, they were able to identify differences between early stages of ovarian cancer and more advanced and aggressive phenotypes.

Their studies showed a mouse's ovarian cells are stiffer and more viscous when they are benign. Increases in cell deformation "directly correlates with the progression from a non-tumor benign cell to a malignant one that can produce tumors and metastases in mice," said Masoud Agah, director of Virginia Tech's Microelectromechanical Systems (MEMS) Laboratory http://www.ece.vt.edu/mems/ and the lead investigator on the study.

Their findings are consistent with a University of California at Los Angeles study that reported lung, breast, and pancreatic metastatic cells are 70 percent softer than benign cells. http://www.nature.com/nnano/journal/v2/n12/full/nnano.2007.388.html

The findings also support Agah group's previous reports on elastic properties of breast cell lines. The digital object identifiers to find the studies on the web are: doi:10.1016/j.biomaterials.2010.05.023 doi:10.1016/j.biomaterials.2010.02.034

Agah worked with Eva Schmelz of Virginia Tech's Department of Human Nutrition, Foods, and Exercise http://www.hnfe.vt.edu/about_us/Bios_faculty/bio_schmelz_eva.html, Chris Roberts of the Virginia-Maryland Reg
'/>"/>

Contact: Lynn Nystrom
tansy@vt.edu
540-231-4371
Virginia Tech
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers engineer functioning small intestine in laboratory experiments
2. Researchers can predict accurately the outcome of pregnancies threatening to miscarry
3. Researchers decipher protein structure of key molecule in DNA transcription system
4. Geneticist receives Excellence in Science Award from coalition of biomedical researchers
5. Researchers predict locations for deer vs. car collisions
6. UBC researchers invent new drug delivery device to treat diabetes-related vision loss
7. U of M researchers contribute to global plant database, expanding ecosystems research
8. Mount Sinai researchers develop new gene therapy for heart failure
9. UCI, French researchers find master switch for adult epilepsy
10. CU researchers develop new software to advance brain image research
11. Duke researchers learn how lung fibrosis begins and could be treated
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers characterize biomechanics of ovarian cells according to phenotype at stages of cancer
(Date:11/4/2014)... PA) – Temple University School of Medicine announced ... winner, an initiative funded by the Bill & ... Professor of Obstetrics, Gynecology and Reproductive Sciences; and ... Temple University School of Medicine will pursue an ... "Maternal Blood Biomarkers to Assess Fetal Neurodevelopment.", Grand ...
(Date:11/4/2014)... newly published research study examining only marketing directed ... fast food restaurants has found that the majority ... exposed to such marketing tactics. , Authored by ... colleagues, the study is the first to examine ... and exterior of fast food restaurants and its ...
(Date:11/4/2014)... HOUSTON – (Nov. 4, 2014) – A majority of ... and that could have serious consequences for the rainforests ... researchers shows the positive impacts lemurs can have on ... impact their disappearance could have on the region,s rich ... rainforest have fruits eaten by lemurs. Lemurs in ...
Breaking Biology News(10 mins):Temple University School of Medicine receives Grand Challenges Explorations grant 2Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... 12 new genes that are somewhat strange bedfellows: Some ... and sleep patterns to small increases in glucose levels ... While these associations are surprising, all the genes ... could help explain conditions that have been a mystery. ...
... in metabolism and diabetes has been suggested in new research ... Wellcome Trust Sanger Institute and the MRC Epidemiology Unit in ... the way the body responds to the 24 hour day-night ... and an increased risk of type 2 diabetes. The results ...
... new study presages a real aim of genetics: to look ... individual genetic variants for individual health. The research team, whose ... novel genetic variants that are associated with lipid levels, a ... of ,genetic microscopes, has increased because the methods are in ...
Cached Biology News:New genes present drug targets for managing cholesterol and glucose levels 2New genes present drug targets for managing cholesterol and glucose levels 3Discovery of new gene associated with diabetes risk suggests link with body clock 2The genetic heart of the lipids 2The genetic heart of the lipids 3
(Date:11/21/2014)... and SAN DIEGO , Nov. 20, 2014 ... President and CEO Marc Hedrick , M.D. will present ...   Thursday, December 4, 2014 TIME:    11:15 am ... or paste this URL into your browser,s address bar: ... pre-register to save time and receive event updates. ...
(Date:11/18/2014)... 18, 2014 Cord Blood Registry® (CBR®) ... 10th Annual World Stem Cell Summit, the largest global meeting ... World Stem Cell Summit will be held December 3-5 at ... . The World Stem Cell Summit ... cures and therapies, convening the most prominent figures in the ...
(Date:11/18/2014)... Cirrascale Corporation ®, a ... rackmount computing infrastructure, today announced it will offer ... its GPU-enabled blade server and high-performance workstation product ... proprietary 80-lane Gen3 PCIe switch-enabled risers, the GB5400 ... dual-GPU accelerator cards in a single blade, allowing ...
(Date:11/18/2014)... San Diego, CA (PRWEB) November 17, 2014 ... Emerson of Salk , Dr. Beverly Emerson, a professor in ... behavior of genes. Her most recent discovery points to an ... about Dr. Emerson’s career and how her local research is ... Emerson will present her findings and then join host Cheryl ...
Breaking Biology Technology:Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 2Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 3Cytori Therapeutics to Provide Corporate Update and Investor Presentation on December 4 through a Live, Interactive Webcast 4Cord Blood Registry Sponsors 2014 World Stem Cell Summit 2Cord Blood Registry Sponsors 2014 World Stem Cell Summit 3Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 2Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 3
... 24 Bone Biologics, Inc. announced today that it,s ... development of a recombinant cell line and initial production ... been developing the protein as a platform technology since ... the lab performed by the founding scientists at ...
... today announced,that the company has obtained an exclusive ... proprietary chiral lipid DOTAP Chloride in,Versamune(TM)-HPV and other ... The use of enantiomerically pure DOTAP Chloride shows ... Eprova AG will be providing,enantiomerically pure DOTAP Chloride ...
... Environment of Care managers can now ... and maintain their organization,s environment of care ... of brief, web-based audio interviews with EC experts called ... download at http://www.eheinc.com/ec_bits.htm feature expert advice to ...
Cached Biology Technology:Bone Biologics Announces UCB-1 (NELL-1) Bone Growth Protein Production Process With Aragen Biosciences 2PDS Biotechnology Corporation Finalizes Commercial Licensing Agreement with Merck Eprova AG to Utilize Merck Eprova's Enantiomers of DOTAP Chloride in Immunotherapies 2Web-based Audio Interviews Keep Environment of Care Managers Up-to-Date on Key EC Compliance Issues 2
Rabbit polyclonal to SpUlp2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: SNNERQSLSSGSND, corresponding to amino acids 622-635 of Schizosaccharomyces pombe SpUlp2...
Lipid Phosphate Phosphohydrolase 2...
Request Info...
Chicken polyclonal to Thioredoxin domain containing 9 ( Abpromise for all tested applications). Antigen: Full length protein (Human) Entrez Gene ID: 10190 Swiss Protein ID: O14530...
Biology Products: