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Researchers capture 'most complete' picture of gene expression in cancer cell cycle
Date:3/6/2014

ony Ly, the lead researcher on the project in Professor Lamond's team, said, "This work provides a better understanding of the complex relationship between the levels of an mRNA and its corresponding protein product. It also demonstrates how it may be possible to detect subtle but important differences between cell types and disease states, including different types of cancer."

The work of the Dundee team providing this new high-resolution mapping of gene expression at the protein level offers great promise also for the future development of safer new drugs. Almost all drugs directly or indirectly affect proteins.

Proteomics the comprehensive detailed analysis of cell proteins is rapidly emerging as the next major phase beyond genome analysis, with great potential to improve our understanding of human disease and help the development of new treatments.

The proteomics research team in Dundee led by Professor Lamond has established a major international role in this new field that is set to soon increase further with the imminent opening of the new Centre for Translational and Interdisciplinary Research (CTIR) building at the University of Dundee.

The CTIR building, due to open this summer, will provide space for a major expansion in proteomics equipment combined with new computing resources for advanced data analysis. This will cement the leading role Dundee has established in advanced protein analysis within the UK.


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Contact: Roddy Isles
r.isles@dundee.ac.uk
44-138-238-4910
University of Dundee
Source:Eurekalert  

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