Navigation Links
Researchers capture bacterial infection on film
Date:7/27/2009

Researchers have developed a new technique that allows them to make a movie of bacteria infecting their living host.

Whilst most studies of bacterial infection are done after the death of the infected organism, this system developed by scientists at the University of Bath and University of Exeter is the first to follow the progress of infection in real-time with living organisms.

The researchers used developing fruit fly embryos as a model organism, injecting fluorescently tagged bacteria into the embryos and observing their interaction with the insect's immune system using time-lapse confocal microscopy.

The researchers can also tag individual bacterial proteins to follow their movement and determine their specific roles in the infection process.

The scientists are hoping to use this system in the future with human pathogens such as Listeria and Trypanosomes. By observing how these bacteria interact with the immune system, researchers will gain a better understanding of how they cause an infection and could eventually lead to better antibacterial treatments.

Dr Will Wood, Research Fellow in the Department of Biology & Biochemistry at the University of Bath, explained: "Cells often behave very differently once they have been taken out of their natural environment and cultured in a petri dish.

"In the body, immune surveillance cells such as hemocytes (or macrophages in vertebrates) are exposed to a battery of signals from different sources. The cells integrate these signals and react to them accordingly.

"Once these cells are removed from this complex environment and cultured in a petri dish these signals are lost. Therefore it is really important to study whole organisms to fully understand how bacteria interact with their host."

Dr Nick Waterfield, co-author on the study and Research Officer at the University of Bath, said: "To be able to film the microscopic battle between single ba
'/>"/>

Contact: Vicky Just
v.j.just@bath.ac.uk
44-122-538-6886
University of Bath
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers capture bacterial infection on film
(Date:7/22/2014)... genus of planthopper known as Conosimus, which now includes ... in the southern part of the Iberian Peninsula in ... appears in the open-access Journal of Insect Science ... Conosimus baenai , has been named after Manuel ... taxonomy of Iberian Hemiptera. , Conosimus baenai ...
(Date:7/21/2014)... Jocelyn Millar , a professor of entomology ... of Chemistry at the University of California, Riverside, ... by the International Society of Chemical Ecology ( ISCE ... Silver Medal is the society,s highest honor. It ... contributions to chemical ecology, the study of chemicals that ...
(Date:7/21/2014)... tracking to monitor seals, every movement, researchers have shown ... drawn to offshore wind farms and pipelines. Those man-made ... grounds, according to a study published in the Cell ... , "I was shocked when I first saw ... Sheringham Shoal," an offshore wind farm in the United ...
Breaking Biology News(10 mins):UC Riverside entomologist receives international honor for chemical ecology contributions 2Seals forage at offshore wind farms 2
... CRUZ, CA--Researchers at the University of California, Santa Cruz, ... from wounds and skin infections, using light to trigger ... developed a photoactive compound that releases nitric oxide when ... biocompatible material that could be applied as a sprayable ...
... percent of their time indoors, but we,re never alone ... of the world,s biomasssome 10 nonillion (1 followed by ... enclosed spaces. So, that,s where the modern microbe hunter ... National Institute of Standards and Technology (NIST) offers guidance ...
... in Action, conference will be held in Copenhagen, ... Europe,s space programme for the GMES Global Monitoring ... European citizens alike. User testimonials of pre-operational ... operational programme and socio-economic assessments will form the ...
Cached Biology News:Light-induced delivery of nitric oxide eradicates drug-resistant bacteria 2Light-induced delivery of nitric oxide eradicates drug-resistant bacteria 3Report details efforts to improve, advance indoor microbial sampling 2
(Date:7/22/2014)... og SHENZHEN , Kina, ... Co., LTD, (BGI Tech), et datterselskab af BGI, ... en ny human whole exome-sekvenseringstjeneste baseret på Complete ... højt anset i branchen for at levere patenterede ... af alle typer varianter, blev købt af BGI ...
(Date:7/22/2014)... , July 22, 2014 Hussey Copper ... MD-Cu 29 antimicrobial copper announces Pullman Regional Hospital,s ... first EPA-registered antimicrobial solid touch surface, at a nominal ... of MRSA, E-coli and other bacteria within 2 hours of ... protecting against bacteria and infectious diseases in its facilities. ...
(Date:7/22/2014)... Quorum Review IRB, the industry leader in central ... called Quick Step™ . The offering went live on ... industry’s need for seamless study start-up with a large volume ... planning 50 or more North American investigator sites, as well ... count of 80 or more. Qualifying studies may also enroll ...
(Date:7/22/2014)... Biofeedback – When a behavioral problem ... medication to best treat it can become a matter ... electroencephalography (EEG) can help predict which medicine will offer ... adverse drug events. , The article “Medication Prediction ... issue of the journal Biofeedback offers evidence that quantitative ...
Breaking Biology Technology:BGI Tech lancerer Human Whole Exome-sekvenseringstjeneste på Complete Genomics avancerede platform 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 3Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 3Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 2Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 3
... this: Web-software services provider Zywave Inc. recently announced ... building being constructed in the Milwaukee County Research Park ... commercial real estate development circles, but the news is more ... story playing out, and an example of how a powerful ...
... Wis. - Claiming that patents and publications used to ... to the isolation and proliferation of human embryonic stem cells, ... response refuting an initial determination by the ... relevancy, made by Carl Gulbrandsen, managing director of WARF, were ...
... - Einstein Wireless , a Wisconsin-based wireless carrier, ... via cell phone about natural disasters, terrorist attacks, and ... its kind in the United States, will use Einstein's ... across most of Wisconsin, and notification equipment from the ...
Cached Biology Technology:Corporate venturing can nurture software success 2Corporate venturing can nurture software success 3Corporate venturing can nurture software success 4Corporate venturing can nurture software success 5Corporate venturing can nurture software success 6WARF questions relevancy of documents used to uphold patent challenge 2WARF questions relevancy of documents used to uphold patent challenge 3
The product contains 2 ml Dynabeads® Epoxy (4.5 μm). Supplied at 4 x 10e8 beads/ml...
... to Endothelin B Receptor Like Protein ... Protein 2 (ETBR-LP-2) has been reported ... isolated from human brain and colon ... peptide (unfortunately, the amino acid sequence ...
... recognized by A300-183A maps to ... of human quaking homolog according ... The epitope is not ... 3, 4, 6, 7 or ...
Flotillin-2 (ESA) Purified Anti-Mouse, Anti-Rat, Anti-Human, Anti-Dog, Anti-Chicken clone 29, Isotype Mouse IgG 1 , 150 µg Consult technical datasheet for details....
Biology Products: