Navigation Links
Researchers at NYU Langone Medical Center review the microbiome and its possible role in cancers
Date:10/21/2011

(New York City, October 20, 2011) In the October 20th edition of the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome.

The authors suggest that the bacteria that reside in us play a crucial role in maintaining our health. This starts early in our lives, when a newborn is "seeded" with bacteria in the birth canal. This relationship changes later in life during our eventual decline and deterioration.

They also show that early exposures to bacteria like H. pylori might protect us early in life but may also be associated with gastric cancers later in life. The authors discuss the potential impact of gut bacterial genes that code for enzymes that metabolize estrogen, which they define as the estrobolome.

"The estrobolome provides a framework for understanding how an individual's resident gut bacteria may modulate lifetime estrogen exposure," said Dr. Plottel. "States of estrogen excess are associated with an increased risk of developing estrogen-related cancers, so knowledge and characterization of the estrabolome represents a novel area of promising scientific and biomedical research."

Dr. Blaser added, "Understanding and harnessing the microbiome will allow us to develop improved preventives, diagnostics, and treatments for many cancers. This is an incredible opportunity for medical science."


'/>"/>

Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers discover that same gene has opposite effects in prostate, breast cancers
2. Researchers do precise gene therapy without a needle
3. Researchers explore planktons shifting role in deep sea carbon storage
4. Stanford researchers examine impact of green politics on recent national elections
5. NIH grant will allow researchers to look for viral cause of most severe form of multiple sclerosis
6. UNH researchers receive NSF grant to scale up stream ecology
7. Medical College of Wisconsin researchers show molecule inhibits metastasis
8. Researchers study agings effect on the brain
9. Notre Dame researchers report progress on compound to treat neurological diseases
10. UNH researchers: Multibeam sonar can map undersea gas seeps
11. Researchers realize high-power, narrowband terahertz source at room temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:4/24/2017)... 2017 Janice Kephart , former ... Strategy Partners, LLP (IdSP) , today issues the ... Trump,s March 6, 2017 Executive Order: Protecting ... can be instilled with greater confidence, enabling the ... refugee applications are suspended by until at least ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. ... company, announces the filing of its 2016 Annual Report on Form ... Exchange Commission. ... Form 10-K is available in the Investor Relations section of the ... on the SEC,s website at http://www.sec.gov . 2016 ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ComplianceOnline’s Medical ... place on 7th and 8th June 2018 in San Francisco, CA. The Summit brings ... well as several distinguished CEOs, board directors and government officials from around the world ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... maternal age to IVF success. , After comparing the results from the fresh ...
(Date:10/10/2017)... , ... October 10, 2017 , ... Dr. Bob Harman, ... his local San Diego Rotary Club. The event entitled “Stem Cells ... and had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human ...
(Date:10/9/2017)... 9, 2017  BioTech Holdings announced today identification ... its ProCell stem cell therapy prevents limb loss ... Company, demonstrated that treatment with ProCell resulted in ... as compared to standard bone marrow stem cell ... in reduction of therapeutic effect.  ...
Breaking Biology Technology: