Navigation Links
Researchers at NYU Langone Medical Center review the microbiome and its possible role in cancers
Date:10/21/2011

(New York City, October 20, 2011) In the October 20th edition of the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome.

The authors suggest that the bacteria that reside in us play a crucial role in maintaining our health. This starts early in our lives, when a newborn is "seeded" with bacteria in the birth canal. This relationship changes later in life during our eventual decline and deterioration.

They also show that early exposures to bacteria like H. pylori might protect us early in life but may also be associated with gastric cancers later in life. The authors discuss the potential impact of gut bacterial genes that code for enzymes that metabolize estrogen, which they define as the estrobolome.

"The estrobolome provides a framework for understanding how an individual's resident gut bacteria may modulate lifetime estrogen exposure," said Dr. Plottel. "States of estrogen excess are associated with an increased risk of developing estrogen-related cancers, so knowledge and characterization of the estrabolome represents a novel area of promising scientific and biomedical research."

Dr. Blaser added, "Understanding and harnessing the microbiome will allow us to develop improved preventives, diagnostics, and treatments for many cancers. This is an incredible opportunity for medical science."


'/>"/>

Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers discover that same gene has opposite effects in prostate, breast cancers
2. Researchers do precise gene therapy without a needle
3. Researchers explore planktons shifting role in deep sea carbon storage
4. Stanford researchers examine impact of green politics on recent national elections
5. NIH grant will allow researchers to look for viral cause of most severe form of multiple sclerosis
6. UNH researchers receive NSF grant to scale up stream ecology
7. Medical College of Wisconsin researchers show molecule inhibits metastasis
8. Researchers study agings effect on the brain
9. Notre Dame researchers report progress on compound to treat neurological diseases
10. UNH researchers: Multibeam sonar can map undersea gas seeps
11. Researchers realize high-power, narrowband terahertz source at room temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2016)... DALLAS , June 20, 2016 ... criminal justice technology solutions for public safety, investigation, ... by the prisons involved, it has secured the ... Corrections (DOC) facilities for Managed Access Systems (MAS) ... (4) additional facilities to be installed by October, ...
(Date:6/7/2016)... 2016  Syngrafii Inc. and San Antonio Credit ... includes integrating Syngrafii,s patented LongPen™ eSignature "Wet" solution ... will result in greater convenience for SACU members ... maintaining existing document workflow and compliance requirements. ... Highlights: ...
(Date:6/1/2016)... -- Favorable Government Initiatives Coupled With Implementation ... to Boost Global Biometrics System Market Through 2021  ... " Global Biometrics Market By Type, By End ... - 2021", the global biometrics market is projected to ... growing security concerns across various end use sectors such ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
(Date:6/23/2016)... 23, 2016 Andrew ... http://doi.org/10.17925/OHR.2016.12.01.22 Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
(Date:6/23/2016)... ... 23, 2016 , ... ClinCapture, the only free validated electronic ... showcase its product’s latest features from June 26 to June 30, 2016 for ... Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug Information ...
(Date:6/23/2016)... ... June 23, 2016 , ... Velocity Products, ... tools designed, tuned and optimized exclusively for Okuma CNC machining centers at The ... of a collaboration among several companies with expertise in toolholding, cutting tools, machining ...
Breaking Biology Technology: