Navigation Links
Researchers at NYU Langone Medical Center review the microbiome and its possible role in cancers

(New York City, October 20, 2011) In the October 20th edition of the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome.

The authors suggest that the bacteria that reside in us play a crucial role in maintaining our health. This starts early in our lives, when a newborn is "seeded" with bacteria in the birth canal. This relationship changes later in life during our eventual decline and deterioration.

They also show that early exposures to bacteria like H. pylori might protect us early in life but may also be associated with gastric cancers later in life. The authors discuss the potential impact of gut bacterial genes that code for enzymes that metabolize estrogen, which they define as the estrobolome.

"The estrobolome provides a framework for understanding how an individual's resident gut bacteria may modulate lifetime estrogen exposure," said Dr. Plottel. "States of estrogen excess are associated with an increased risk of developing estrogen-related cancers, so knowledge and characterization of the estrabolome represents a novel area of promising scientific and biomedical research."

Dr. Blaser added, "Understanding and harnessing the microbiome will allow us to develop improved preventives, diagnostics, and treatments for many cancers. This is an incredible opportunity for medical science."


Contact: Lorinda Klein
NYU Langone Medical Center / New York University School of Medicine

Page: 1

Related biology news :

1. Researchers discover that same gene has opposite effects in prostate, breast cancers
2. Researchers do precise gene therapy without a needle
3. Researchers explore planktons shifting role in deep sea carbon storage
4. Stanford researchers examine impact of green politics on recent national elections
5. NIH grant will allow researchers to look for viral cause of most severe form of multiple sclerosis
6. UNH researchers receive NSF grant to scale up stream ecology
7. Medical College of Wisconsin researchers show molecule inhibits metastasis
8. Researchers study agings effect on the brain
9. Notre Dame researchers report progress on compound to treat neurological diseases
10. UNH researchers: Multibeam sonar can map undersea gas seeps
11. Researchers realize high-power, narrowband terahertz source at room temperature
Post Your Comments:
(Date:10/29/2015)... , Oct. 29, 2015   MedNet Solutions ... the entire spectrum of clinical research, is pleased to ... High Tech Association (MHTA) as one of only three ... the "Software – Small and Growing" category. The Tekne Awards ... who have shown superior technology innovation and leadership. ...
(Date:10/29/2015)... 2015  Connected health pioneer, Joseph C. Kvedar ... technology-enabled health and wellness, and the business opportunities that ... The Internet of Healthy Things . Long before ... existed, Dr. Kvedar, vice president, Connected Health, Partners HealthCare, ... moving care from the hospital or doctor,s office into ...
(Date:10/27/2015)... October 27, 2015 Munich, ... Gaze Mapping technology (ASGM) automatically maps data from mobile ... Glasses , so that they can be quantitatively ... Munich, Germany , October 28-29, 2015. ... data from mobile eye tracking videos created with ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... CITY , Nov. 25, 2015 /PRNewswire/ - Aeterna ... affirms that its business and prospects remain fundamentally ... , Zoptrex™ (zoptarelin doxorubicin) recently received DSMB recommendation ... to completion following review of the final interim ... Phase 2 Primary Endpoint in men with heavily ...
(Date:11/25/2015)... 25, 2015 Orexigen® Therapeutics, Inc. (Nasdaq: ... a fireside chat discussion at the Piper Jaffray 27th ... . The discussion is scheduled for Wednesday, December 2, ... .  A replay will be available for 14 days ... , Julie NormartVP, Corporate Communications and Business Development , ...
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and ... early in their initial angel funding process. Now, they are paying it forward ... make early stage investments in the microbiome space. In this, they join ...
(Date:11/24/2015)... ... 24, 2015 , ... The United States Golf Association (USGA) today announced Dr. ... Award. Presented annually since 1961, the USGA Green Section Award recognizes an individual’s distinguished ... , Clarke, of Iselin, N.J., is an extension specialist of turfgrass pathology in ...
Breaking Biology Technology: