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Researchers apply systems biology and glycomics to study human inflammatory diseases
Date:10/28/2008

e new hypotheses that can be tested experimentally.

"Such an interative approach, using computational and experimental tools, can provide clues as to what reactions must be perturbed in order to alter the carbohydrate structure on cell surfaces in a defined manner," he explained.

The UB researchers noted that their computational and experimental approaches to the problem provide them with a unique insight.

"It's an extremely valuable way to apply engineering principles to biology, it's critical to merge both approaches," said Neelamegham.

In addition to providing new insights for the ultimate development of new drugs and therapeutic strategies, the UB research also is relevant to sectors of the biotech industry, which aim to apply glycan engineering principles during product development.


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Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-5000 x1415
University at Buffalo
Source:Eurekalert

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