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Researchers across North America team up to find genetic markers for autism
Date:4/18/2012

(Edmonton) A medical researcher at the University of Alberta is working with scientists from across North America to find out if there are genetic markers for autism. More than 15 scientists will examine DNA samples from children with autism and their infant siblings to see if the siblings are at high risk.

And if siblings are at high risk for developing autism, could intervention start before symptoms develop?

If theres a family of a child with autism, they of course wonder what the risk for the younger infant is, says Lonnie Zwaigenbaum, a U of A researcher with the Department of Pediatrics in the Faculty of Medicine & Dentistry, who is the principal investigator for the two-year study.

We want to know if its possible to use genetic biomarkers as a way of giving these families a more accurate estimate of what that siblings risk is. If there was a way of using genetic biomarkers to identify infants at high-risk before the more overt manifestations of autism were obvious, it would really open the door to provide support and intervention at earlier stages of development.

According to the Autism Speaks Canadian website, autism, part of a group of disorders known as Autism Spectrum Disorders (ASD), is a complex neurobiological disorder that typically lasts throughout a persons lifetime. The disorder is characterized by varying degrees of impairment in communication skills and social abilities, and also by repetitive behaviors. Autism, which is more common among boys than girls, affects 1 in 88 children, according to the Centers for Disease Control and Prevention.

Zwaigenbaum is working with scientists in Toronto, Hamilton, Halifax and various American universities including: the University of Washington, UC Davis, Vanderbilt, UC San Diego, Kennedy Krieger Institute/Johns Hopkins University, and the University of Miami.

This research initiative is funded by the Simons Found
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Contact: Raquel Maurier
raquel.maurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

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