Navigation Links
Researcher tests promising drug on those with Down syndrome
Date:8/2/2011

AURORA, Colo. (Aug. 1, 2011) A University of Colorado School of Medicine scientist is completing a major clinical trial on a drug that could boost cognitive function in those with Down syndrome, significantly improving their quality of life and representing a potential milestone in research on this genetic condition.

"We are hoping to enhance memory and learning in those with Down syndrome," said Alberto Costa, MD, PhD, an associate professor of medicine and the neuroscientist leading the effort. "We have been studying this drug for three years and are now ready to analyze the data on our trial. Our team at the University of Colorado and Children's Hospital Colorado expects to have the results in the next two or three months."

Costa, whose work was chronicled in last Sunday's New York Times Magazine, is testing the drug memantine, currently used to relieve symptoms of Alzheimer's disease, in 39 people with Down syndrome. About half received the drug and the others a placebo. In 2007, Costa demonstrated that memantine could improve memory function in mice with Down syndrome.

And now, for the first time, he is taking a drug effective in the treatment of learning and memory deficits in mice with Down syndrome and applying it to humans, a move described by the New York Times as "a milestone in the history of Down syndrome research."

Costa is no disinterested researcher. His 16-year-old daughter Tyche named for the Greek goddess of Fortune - has Down syndrome. Like others with the condition, she faces the specter of a steady decline in mental functioning as she gets older and a roughly 20 percent chance of getting Alzheimer's in her 50's. After that diagnosis, death is often just five years away.

"I feel I am racing the clock to find something that will at least keep her functioning at the level she is at now," Costa said. "As they age, parts of their brain will shrink and their functions will diminish."

Costa
'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-315-6374
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related biology news :

1. U of M researchers use improved imaging technique; discover a better approach to diagnosing epilepsy
2. RUB researchers decipher the molecular basis of blue-green algae
3. Researchers discover the mechanism that determines cell position in the intestinal epithelium
4. Caltech researchers increase the potency of HIV-battling proteins
5. Researchers tap yeasts as source of green surfactants
6. Lawson researchers take control of cancer
7. U researchers look to dogs to better understand intricacies of bone cancer
8. Penn researchers help graft olfactory receptors onto nanotubes
9. U of M researchers may have discovered key to help women fight infections during pregnancy
10. Behavior 2011 to draw global contingent of more than 1,100 animal researchers to IU next week
11. U of M researchers discover gene required to maintain male sex throughout life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the addition ... Systems Market" report to their offering. ... security market is estimated to grow at a CAGR of ... a larger share in this market, Canada ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB SM ... (GCP) audit to confirm its adherence to current U.S. ... HITLAB to conduct regulated smart device and smart phone ... and research quality. "HITLAB is determined to ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... advances in technology, it is important to upgrade biometric ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... an Applera Corporation business, today announced the introduction ... Provider Program, a new program for service providers ... solution for gene expression analysis, including the highly ... and gold-standard TaqMan® Gene Expression Assays for target ...
... an organization dedicated to humane alternatives to the use of ... your own that requires using animals as part of the ... Physicians Committee for Responsible Medicine, you invent your own test. ... has developed the world's first cruelty-free insulin assay, a test ...
... today that they have entered into a non-exclusive ... customers with new software solutions for GeneChip(R) data ... develop a new software package for Affymetrix, ArrayAssist(R) ... statistical analysis solution of Affymetrix gene expression microarrays. ...
Cached Biology News:Harnessing microbes, one by one, to build a better nanoworld 2PCRM develops world's first cruelty-free insulin assay 2Affymetrix and Stratagene Announce Strategic Software Alliance 2
(Date:1/22/2015)... Mass (PRWEB) January 21, 2015 Cambridge Semantics, ... Web technology, today announced that 2014 was a record-breaking year ... the capabilities of the Anzo Smart Data Platform and our ... and utilize insights from diverse data which led to record ...
(Date:1/22/2015)... January 22, 2015 Pipette.com has added ... to their comprehensive portfolio of Eppendorf products. , The ... purchase a Centrifuge 5424/5424 R and receive the following:, ... Eppendorf Research plus or Eppendorf Reference 2 , ...
(Date:1/22/2015)... 22, 2015 Selexis SA, a serial ... Cell Banks (RCBs) used for drug discovery to commercial ... will include Next-Generation Sequencing (NGS) data packages. ... biologic manufacturing by ensuring the integrity of the gene, ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... been honored for its commitment to sustainability with inclusion on ... is the highest ranked healthcare equipment company among the Corporate ... the World Economic Forum at Davos, Switzerland ...
Breaking Biology Technology:Cambridge Semantics Announces Record Results for 2014 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Varian Honored Among World's 100 Most Sustainable Corporations 2
... , , , ... (GSK) (NYSE: GSK ) today announced that it has completed ... share capital of Stiefel for a cash consideration of $2.9 billion. ... of the agreement, GSK may be obligated to make additional cash payments ...
... ... SBIR grants from the National Institutes of Health to develop original in silico technologies to ... rates of DNA and RNA experiments. , ... (Vocus) July 22, 2009 -- DNA Software, Inc. has been awarded three Fast ...
... , , PHILADELPHIA and LONDON, ... and often cited compendium of pharmaceutical research and development statistics, the ... year,s Factbook offers extended content including patent information and ... "The R&D Factbook provides the data that ...
Cached Biology Technology:GlaxoSmithKline Completes Acquisition of Stiefel 2DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies 2DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies 3DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies 4Thomson Reuters Announces 2009 Edition of the CMR International Pharmaceutical R&D Factbook 2
Originally developed for the culture of Drosophila; suitable for culture of other dipteran cell lines. Powder, Insect cell culture tested...
... is a new product number, ... product number. If showing no ... the old Sigma-Aldrich number (C7046) ... assistance. Mfr Desig: Corning ...
... Disposable. Virgin, optically clear polystyrene ... and alphanumeric coordinates for cell counting. ... number is a new product number, ... number. If showing no availability yet, ...
... ® Ek Adaptor encodes a T7 ... site (rbs), ATG translation initation codon, and ... is a small epitope tag (11 aa) ... target protein with T7•Tag Monoclonal Antibody and ...
Biology Products: