Navigation Links
Researcher says microchannels could advance tissue engineering methods
Date:8/17/2009

as a stored electrical charge is released. This branching pattern occurs on the surface or interior of insulating materials during an electric discharge.

The patterns are similar to the branching patterns seen in a lightning strike. They also can be seen on the skin of lightning-strike victims or on the ground at the point where a lightning strike occurred. A more common example of this effect can be seen in crystal blocks that are often sold as decorative pieces.

Observing these patterns, Ugaz saw the similarities to the artificial network he envisioned creating and wondered if liquid could be transported through these branching pathways, similar to the way nutrients are transported through a tree's vasculature.

He went to work, teaming with Texas A&M's National Center for Electron Beam Research to implant a high level of electric charge inside an acrylic block using electron beam irradiation. When a point of release for the charge was created, Ugaz was left with the expected fractal patterns.

In his laboratory, he and his research group continue to account for such variables as size, range of size, angles, average area ratios and diameters, as well as how all of this relates to the intensity and frequency of charge. Together with Jayaraman, Ugaz is working to translate these microchannels into a biomedical application.

Their work appears promising. So far, the team has found that these fractal pathways can indeed serve as an elaborate vasculature that is capable of sustaining transport in manner suited for tissue engineering purposes. What's more, by adjusting certain variables, Ugaz can reliably reproduce these architectures not only in acrylic blocks but in biodegradable porous materials that allow for cell cultures to be embedded in the area surrounding the vasculature. He's even begun widening the vascular channels to facilitate flow through them and interconnecting separate networks to form larger vasculatures.

And unlike other m
'/>"/>

Contact: Victor Ugaz
ugaz@tamu.edu
979-458-1002
Texas A&M University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Researchers find genetic link between physical pain and social rejection
2. UTSA biology researchers demystify elusive war zone bacterium
3. UGA researchers propose model for disorders caused by improper transmission of chromosomes
4. Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
5. NIH-funded researchers sequence exomes of 12 people
6. USC researchers identify regulatory genetic sequences that may predict risk for prostate cancer
7. K-State lab gives researchers the tools to study porcine circovirus associated diseases
8. Hebrew U. researchers shed light on the brain mechanism responsible for processing of speech
9. SLAC researchers reveal the dance of water
10. McGill/JGH researchers successfully reverse multiple sclerosis in animals
11. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... the fist-like club of a mantis shrimp, a team ... collaboration with University of Southern California and Purdue University, ... is more impact resistant and tougher than the standard ... club of this tiny crustacean, the more we realize ... every day," said David Kisailus, a Kavli Fellow of ...
(Date:4/22/2014)... University of Kentucky has discovered new methods to build ... The research, led by Peixuan Guo, professor and ... College of Pharmacy and Markey Cancer Center, is reported ... Polymer Material To Build Robust Structures with Defined Shape ... L. Jasinski. , The article, which will appear in ...
(Date:4/22/2014)... French . , ... complete genome and subsequent phylogenetic analysis show that the ... is distinct from strains previously identified in the Democratic ... linked the laboratory confirmed cases with the initial deaths ... is a lethal, highly contagious virus for which there ...
Breaking Biology News(10 mins):Mantis shrimp stronger than airplanes 2Mantis shrimp stronger than airplanes 3RNA shows potential as boiling-resistant anionic polymer material for nanoarchitectures 2Inserm and the Institut Pasteur identify a new variant of Ebola virus in Guinea 2
... HOUSTON -- (Feb. 11, 2013) -- Cancer researchers from Rice ... effective at killing cancer and drug-resistant bacteria could best deliver ... from naturally occurring toxins. "One of the oldest ... your opponent with one attack and deliver a knockout blow ...
... reached a decade high in 2012, while worldwide fatalities remained ... File report released today. The U.S. saw an upturn ... seven fatalities worldwide, which is lower than 2011 but higher ... It is the second consecutive year for multiple shark attacks ...
... The Federation of American Societies for Experimental Biology (FASEB) ... Conference (SRC): Melatonin Biology: Actions & Therapeutics. ... Therapeutics is an important and unique scientific conference where ... molecule and a physiological marker of circadian phase will ...
Cached Biology News:1-2 punch strategy against bacteria and cancer 21-2 punch strategy against bacteria and cancer 3University of Florida reports 2012 US shark attacks highest since 2000 2University of Florida reports 2012 US shark attacks highest since 2000 3
(Date:1/15/2014)... 15, 2014 Look inside the new ... for the lab, from fluid handling to instruments to ... ship when you order. , Preferred Solutions features ... from the L/S® model for precise flow control and ...
(Date:1/15/2014)... 2014 ­ RedBrick Health , a fast-growing leader ... announces that EmblemHealth , the New ... now providing the RedBrick Compass health assessment, combined with ... of its members. EmblemHealth is among the first health ...
(Date:1/15/2014)... TX (PRWEB) January 15, 2014 More ... disease, and about 1 in 3 seniors will die ... source ). These jaw-dropping figures have shocked many Americans ... and, hopefully, help prevent these tragic age-related cognitive disorders. ...
(Date:1/15/2014)... DTS Language Services, Inc . is pleased to announce ... organizations who need document translations. Clients will now have ... in advance with a selection of nearly 50 life science ... critical factor in clinical and scientific fields, and decrease the ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2DTS Improves Efficiency for Life Science Document Translations 2
... , For transfection of a wide variety of cells, , ... Features and benefits , , ... for most cell lines , Transfection in the presence of serum ... High transfection efficiencies and minimal cytotoxicity, ...
... , , , , ... gene silencing in eukaryotic cell culture by targeting complementary endogenous ... enables targeted gene , silencing in functional genomics ... oligonucleotide synthesis service that includes a range of modifications , ...
... , , Frank Narz, Silke Janhsen, and Ute ... , Primary neurons are extremely ... by delivery of either siRNA or plasmid DNA challenging , ... of endogenous genes in primary rat hippocampal and cortical neurons using , ...
Cached Biology Technology:Effectene Transfection Reagent 2Effectene Transfection Reagent 3Effectene Transfection Reagent 4Custom and library siRNA for efficient gene silencing 2Custom and library siRNA for efficient gene silencing 3Custom and library siRNA for efficient gene silencing 4Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 2Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 3Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 4Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 5Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 6
These Costar 96-well, flat-bottom polystyrene EIA plates are used for EIAs, ELISAs, and other protein binding assays. Supplied as box of 100 (20 packages; 5 plates per package)....
... Assay provides a convenient method to probe conformational ... MDR1 substrates. Thus, the kit may be used ... act as transport substrates for MDR1. Because UIC2 ... MDR1 substrates, the MDR1 Shift Assay can be ...
... The wide and long ... of Polaroid gel documentation systems. ... holds the camera in place ... that allows photography on the ...
... are derived from Paraffin embedded tissue blocks, ... procedures to ensure the highest quality. Tissues ... one block, sectioned at a thickness of ... Sections are large (3-5 mm in diameter) ...
Biology Products: