Navigation Links
Researcher says microchannels could advance tissue engineering methods
Date:8/17/2009

ue engineering as the ability to provide nutrients to all depths of growing tissue is extremely critical," says Jayaraman, assistant professor in the department. "Typically, as the tissue grows, the inner regions tend to be nutrient-limited, which affects the overall viability of the tissue-engineered product. The development of 3-D vascular networks in bio-compatible materials addresses this specific need in the tissue engineering community."

Without such a network in place, the tissue created by engineers is dependent upon diffusion for the transport of nutrients and waste products. Diffusion, however, is a slow process, taking about 17 minutes to traverse a span of 200 microns, or about twice the thickness of a human hair. Increase that distance to an inch, and it takes close to four months for diffusion to occur. That length of time won't support cell growth, Ugaz notes.

"That's just a fundamental limit of this diffusion mechanism the timescale," Ugaz says. "If your aim is to manufacture artificial organs, you'll need a network that has the ability to supply all of the cells in a three-dimensional volume with nutrients while moving waste products out and keeping these processes going in a certain timescale.

"The way this is all accomplished [in nature] is with a type of branched network, similar to how a tree is naturally structured. There is a trunk, and distribution occurs throughout a large volume by branches of various lengths and thicknesses that emanate from that trunk. This allows transport to penetrate inside a large volume, until the distance between branches and stems is minimized. It's all really an issue of transport."

Framing the challenge in those terms, Ugaz began contemplating how such a complex architecture could be artificially mimicked. He was well aware of a phenomenon known as the Lichtenberg effect. Named after German physicist Georg Christoph Lichtenberg, the effect is responsible for the creation of a fractal pattern
'/>"/>

Contact: Victor Ugaz
ugaz@tamu.edu
979-458-1002
Texas A&M University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Researchers find genetic link between physical pain and social rejection
2. UTSA biology researchers demystify elusive war zone bacterium
3. UGA researchers propose model for disorders caused by improper transmission of chromosomes
4. Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
5. NIH-funded researchers sequence exomes of 12 people
6. USC researchers identify regulatory genetic sequences that may predict risk for prostate cancer
7. K-State lab gives researchers the tools to study porcine circovirus associated diseases
8. Hebrew U. researchers shed light on the brain mechanism responsible for processing of speech
9. SLAC researchers reveal the dance of water
10. McGill/JGH researchers successfully reverse multiple sclerosis in animals
11. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... ,Models of Life, is a non-traditional biophysics textbook and ... book is a journey of discovery into biological systems ... and biological regulation. It is about how our genes ... between the billions of cells in an organism. It ... between principles, which can be found on both large ...
(Date:10/15/2014)... in female mice to an enzyme activated by the ... resistant to respiratory infections than males. Now, an international ... bacterial pneumonia in female mice is linked to the ... that this enzyme is ultimately activated by the release ... lead by Professor Lester Kobzik at the Harvard University ...
(Date:10/15/2014)... 15, 2014   Neurotechnology , a provider ... availability of the VeriLook Surveillance 3.0 software ... real-time biometric face identification using live video streams ... The new version not only identifies faces in ... objects while they are moving through the video ...
Breaking Biology News(10 mins):New book about life as seen from physics 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3
... of tissue damage depends on the balance between the generation ... In a significant minority of people who get injury to ... can progress to chronic liver disease and cirrhosis where the ... blood or produce vital hormones and clotting factors. Liver scars ...
... how autism miswires the brain are emerging from a ... disorders that affects fewer than 20 people worldwide. ... National Institutes of Health have grown patients, skin cells ... brain in Timothy Syndrome. Affected children often show symptoms ...
... about the importance of proteins called B-type lamins in the ... different varieties of cells. New research from a team led ... B-type lamins are not necessary for stem cells to renew ... work is published November 24 by Science Express. ...
Cached Biology News:Neurons grown from skin cells may hold clues to autism 2Neurons grown from skin cells may hold clues to autism 3Surprise role of nuclear structure protein in development 2
(Date:10/19/2014)... 19, 2014 The report "Unmanned ... Homeland Security), Technology, Payload, Type & by Geography ... the global unmanned ground vehicle market into various ... of market sizes. The report also identifies the ... impacting it along with the adoption trends. , ...
(Date:10/18/2014)... The Asia-Pacific Bio-based Advanced Phase Change Materials Market ... change material market in Asia-Pacific with analysis and ... of the Asia-Pacific Bio-based Advanced Phase Change Materials ... in-depth analysis provided. This also provides a glimpse ... phase change material market, and is supported by ...
(Date:10/18/2014)... The Asia-Pacific hardware encryption display market report defines ... and forecast of revenue. This market was valued $5,154.0 ... million by 2018, at a CAGR of 58.4% from ... the Asia-Pacific hardware encryption market report, to get an ... a glimpse of the segmentation of the market, and ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... rate in the five years to 2014. The industry's ... renewable energy tax credits that encouraged the use of ... renewable portfolio standards (RPSs), which require local utilities to ... their total energy portfolio. Increased campaigning for green technology ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 4The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 3Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3
... , SAN DIEGO, Sept. 14 aTyr ... class of naturally occurring proteins as biotherapeutics, will present at ... Friday, September 18th. Jeff Watkins, CEO of aTyr Pharma, ... and lead program based on naturally occurring resected proteins of ...
... ATLANTA, Sept. 14 CryoLife, Inc. (NYSE: ... tissue processing company, announced today that it is scheduled to participate ... Hyatt New York in New York City. , , ... Inc., will present Monday, September 21 at 2:00 p.m., Eastern Time. ...
... ... of protein expression, many researchers have abandoned cloning in favor of synthetic genes, ... Unlike a natural gene, a synthetic gene can be designed to use any ... huge advantage, as most researchers have come to accept that "codon optimization" can ...
Cached Biology Technology:aTyr Pharma to Present at BioPharm America 2009 2CryoLife to Present at UBS Global Life Sciences Conference 2DNA2.0 Unlocks The Secrets Of Optimized Gene Design: Company Identifies Codon Choice Design Principles for Optimal Protein Expression 2DNA2.0 Unlocks The Secrets Of Optimized Gene Design: Company Identifies Codon Choice Design Principles for Optimal Protein Expression 3DNA2.0 Unlocks The Secrets Of Optimized Gene Design: Company Identifies Codon Choice Design Principles for Optimal Protein Expression 4
The Protein Kinase Factsbooks (2 Volume Set)...
... M. Walker (1996) • This book ... for studying proteins and peptides. Each ... step-by-step instruction, timesaving troubleshooting tips, alternative ... of reagents and suppliers. Topics covered ...
All serum is collected from U.S.D.A. fryers and broilers. Pricing: $15/unit for 1 - 10 units; $12/unit for 11 - 50 units...
...
Biology Products: