Navigation Links
Researcher finds revolutionary way to treat eye cancer
Date:8/27/2010

AURORA, Colorado (August 27, 2010) Rare but devastating, eye cancer can strike anyone at any time and treating it often requires radiation that leaves half of all patients partially blind.

But a new technique developed by Scott Oliver, MD, assistant professor at the University of Colorado School of Medicine, may change all that.

Oliver has discovered that silicone oil applied inside the eye can block up to 55 percent of harmful radiation, enough to prevent blindness in most patients.

His findings, published in the July issue of the Archives of Ophthalmology, may revolutionize the way eye cancer is treated.

"If you get diagnosed with eye cancer you want to know, `Is this going to kill me? Is this going to make me go blind?''' said Oliver, director of the Ophthalmic Oncology Center at the Rocky Mountain Lions Eye Institute on the University of Colorado's Anschutz Medical Campus. "I believe this treatment will allow you to keep your eye and keep your vision."

Oliver focused on choroidal melanoma of the eye or uveal cancer, the most common and dangerous form of a disease that strikes over 2,000 people each year. It can spread quickly to the liver and lungs which is often fatal. The cancer can occur in people of any age - fair skin and sun exposure are thought to be a leading cause.

Physicians often treat it with a technique called plaque brachytherapy. Surgeons attach a gold cap containing radioactive seeds to the white part of the eye. For one week the radiation slowly incinerates the tumor but it also causes long-term damage.

"Radiation injures blood vessels and nerves in the back of the eye," Oliver said. "Half of all patients are legally blind in three years in the treated eye."

In his quest to save their eyesight, Oliver experimented with a series of substances that would block radiation from striking critical structures while allowing it to hit the tumor. He discovered that silicone oil, already used to treat retinal detachment, could screen out a majority of harmful radiation.

"You don't have to block out all the radiation to protect the eye because the vital structures in the eye can tolerate low doses of radiation," he said.

Oliver experimented on cadaver eyes and tested the oil on animals in the laboratory and found no harmful side-effects.

"We are now at the point where we can embark on a clinical trial," he said. "This is a significant development in the way we treat this disease. In the past, we could save the eye with radiation but we saved vision only half the time. With this treatment, I believe we will do much better in the future."


'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-503-7990
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Researchers discover novel mechanism protecting plants against freezing
2. UK researchers release draft sequence coverage of wheat genome
3. 2 Hispanic researchers from Argonne receive national acclaim
4. LSU expert teams with Ohio State researcher to track species affected by Gulf oil spill
5. Researchers find gene responsible for neurodegenerative disease in dogs, possibly in humans
6. Researchers study cinnamon extracts
7. K-state researchers explore physiological effects of space travel with NASA grant
8. Researchers connect APC protein to autism and mental retardation
9. MIT researchers develop a better way to grow stem cells
10. U of M researchers identify 2 FDA approved drugs that may fight HIV
11. Researchers advance understanding of enzyme that regulates DNA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2017)... DUBLIN , Feb 10, 2017 ... PharmaBiotech,s new report "Personalized Medicine - Scientific and Commercial ... ... in personalized medicine. Diagnosis is integrated with therapy for selection ... emphasis on early detection and prevention of disease in modern ...
(Date:2/8/2017)... About Voice Recognition Biometrics Voice recognition biometrics ... a stored voiceprint template. Acoustic features of an ... are compared to distinguish between individual voices. Voice ... PCs already have a microphone and can authenticate ... are most likely to be deployed in telephone-based ...
(Date:2/8/2017)... Report Highlights ... The global synthetic-biology market reached nearly $3.9 billion in ... a compound annual growth rate (CAGR) of 24.0% through 2021. ... for synthetic biology. - Analyses of global market trends, with ... annual growth rates (CAGRs) through 2021. - Coverage of core ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... 2017  VWR Corporation (NASDAQ: VWR), the leading global independent ... customers, today reported its financial results for the fourth quarter ... 4Q16 record quarterly net sales of ... organic basis. 4Q16 EMEA-APAC segment ... while the Americas net sales increased 2.5%, or down 0.9% ...
(Date:2/23/2017)... ... February 23, 2017 , ... BellBrook Labs is ... include an array of biochemical analyses critical for Lead Discovery. The company’s ... and SAR programs, including inhibitor potency and selectivity, mechanism of action, and inhibitor ...
(Date:2/23/2017)... upscale Capitol Hill neighborhood, with its swanky shops, parks and cafés, ... treatment salon to set up shop. But there,s Hair ... bistro on E Madison Ave, and CEO Maria Botham ... clinic, we pride ourselves on being a destination for parents ... stigma associated with lice. Everyone can get lice – it ...
(Date:2/23/2017)... ... February 23, 2017 , ... David Nolte, ... Recognition Reception at Purdue Research Park of West Lafayette, Indiana. , ... of outstanding contributions to, and success with, commercializing discoveries from Purdue research. “This ...
Breaking Biology Technology: