Navigation Links
Researcher finds revolutionary way to treat eye cancer
Date:8/27/2010

AURORA, Colorado (August 27, 2010) Rare but devastating, eye cancer can strike anyone at any time and treating it often requires radiation that leaves half of all patients partially blind.

But a new technique developed by Scott Oliver, MD, assistant professor at the University of Colorado School of Medicine, may change all that.

Oliver has discovered that silicone oil applied inside the eye can block up to 55 percent of harmful radiation, enough to prevent blindness in most patients.

His findings, published in the July issue of the Archives of Ophthalmology, may revolutionize the way eye cancer is treated.

"If you get diagnosed with eye cancer you want to know, `Is this going to kill me? Is this going to make me go blind?''' said Oliver, director of the Ophthalmic Oncology Center at the Rocky Mountain Lions Eye Institute on the University of Colorado's Anschutz Medical Campus. "I believe this treatment will allow you to keep your eye and keep your vision."

Oliver focused on choroidal melanoma of the eye or uveal cancer, the most common and dangerous form of a disease that strikes over 2,000 people each year. It can spread quickly to the liver and lungs which is often fatal. The cancer can occur in people of any age - fair skin and sun exposure are thought to be a leading cause.

Physicians often treat it with a technique called plaque brachytherapy. Surgeons attach a gold cap containing radioactive seeds to the white part of the eye. For one week the radiation slowly incinerates the tumor but it also causes long-term damage.

"Radiation injures blood vessels and nerves in the back of the eye," Oliver said. "Half of all patients are legally blind in three years in the treated eye."

In his quest to save their eyesight, Oliver experimented with a series of substances that would block radiation from striking critical structures while allowing it to hit the tumor. He discovered that silicone oil, already used to treat retinal detachment, could screen out a majority of harmful radiation.

"You don't have to block out all the radiation to protect the eye because the vital structures in the eye can tolerate low doses of radiation," he said.

Oliver experimented on cadaver eyes and tested the oil on animals in the laboratory and found no harmful side-effects.

"We are now at the point where we can embark on a clinical trial," he said. "This is a significant development in the way we treat this disease. In the past, we could save the eye with radiation but we saved vision only half the time. With this treatment, I believe we will do much better in the future."


'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-503-7990
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Researchers discover novel mechanism protecting plants against freezing
2. UK researchers release draft sequence coverage of wheat genome
3. 2 Hispanic researchers from Argonne receive national acclaim
4. LSU expert teams with Ohio State researcher to track species affected by Gulf oil spill
5. Researchers find gene responsible for neurodegenerative disease in dogs, possibly in humans
6. Researchers study cinnamon extracts
7. K-state researchers explore physiological effects of space travel with NASA grant
8. Researchers connect APC protein to autism and mental retardation
9. MIT researchers develop a better way to grow stem cells
10. U of M researchers identify 2 FDA approved drugs that may fight HIV
11. Researchers advance understanding of enzyme that regulates DNA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2016)... Securus Technologies, a leading provider of ... safety, investigation, corrections and monitoring announced that after ... secured the final acceptance by all three (3) ... Systems (MAS) installed. Furthermore, Securus will have contracts ... by October, 2016. MAS distinguishes between legitimate wireless ...
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. and ... business relationship that includes integrating Syngrafii,s patented LongPen™ ... project. This collaboration will result in greater convenience ... credit union, while maintaining existing document workflow and ... ...
(Date:6/1/2016)... NEW YORK , June 1, 2016 ... Biometric Technology in Election Administration and Criminal Identification to ... According to a recently released TechSci Research report, " ... Sector, By Region, Competition Forecast and Opportunities, 2011 - ... $ 24.8 billion by 2021, on account of growing ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 Houston Methodist Willowbrook Hospital has ... Association to serve as their official health care ... Willowbrook will provide sponsorship support, athletic training services, ... coaches, volunteers, athletes and families. "We ... Association and to bring Houston Methodist quality services ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry ... Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s mission ... hardware projects are designed, built and brought to market. , The Design Lab ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
(Date:6/23/2016)...  Amgen (NASDAQ: AMGN ) today announced ... life sciences incubator to accelerate the development of new ... at QB3@953 was created to help high-potential life science ... early stage organizations - access to laboratory infrastructure. ... two "Amgen Golden Ticket" awards, providing each winner with ...
Breaking Biology Technology: