Navigation Links
Researcher finds revolutionary way to treat eye cancer
Date:8/27/2010

AURORA, Colorado (August 27, 2010) Rare but devastating, eye cancer can strike anyone at any time and treating it often requires radiation that leaves half of all patients partially blind.

But a new technique developed by Scott Oliver, MD, assistant professor at the University of Colorado School of Medicine, may change all that.

Oliver has discovered that silicone oil applied inside the eye can block up to 55 percent of harmful radiation, enough to prevent blindness in most patients.

His findings, published in the July issue of the Archives of Ophthalmology, may revolutionize the way eye cancer is treated.

"If you get diagnosed with eye cancer you want to know, `Is this going to kill me? Is this going to make me go blind?''' said Oliver, director of the Ophthalmic Oncology Center at the Rocky Mountain Lions Eye Institute on the University of Colorado's Anschutz Medical Campus. "I believe this treatment will allow you to keep your eye and keep your vision."

Oliver focused on choroidal melanoma of the eye or uveal cancer, the most common and dangerous form of a disease that strikes over 2,000 people each year. It can spread quickly to the liver and lungs which is often fatal. The cancer can occur in people of any age - fair skin and sun exposure are thought to be a leading cause.

Physicians often treat it with a technique called plaque brachytherapy. Surgeons attach a gold cap containing radioactive seeds to the white part of the eye. For one week the radiation slowly incinerates the tumor but it also causes long-term damage.

"Radiation injures blood vessels and nerves in the back of the eye," Oliver said. "Half of all patients are legally blind in three years in the treated eye."

In his quest to save their eyesight, Oliver experimented with a series of substances that would block radiation from striking critical structures while allowing it to hit the tumor. He discovered that silicone oil, already used to treat retinal detachment, could screen out a majority of harmful radiation.

"You don't have to block out all the radiation to protect the eye because the vital structures in the eye can tolerate low doses of radiation," he said.

Oliver experimented on cadaver eyes and tested the oil on animals in the laboratory and found no harmful side-effects.

"We are now at the point where we can embark on a clinical trial," he said. "This is a significant development in the way we treat this disease. In the past, we could save the eye with radiation but we saved vision only half the time. With this treatment, I believe we will do much better in the future."


'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-503-7990
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Researchers discover novel mechanism protecting plants against freezing
2. UK researchers release draft sequence coverage of wheat genome
3. 2 Hispanic researchers from Argonne receive national acclaim
4. LSU expert teams with Ohio State researcher to track species affected by Gulf oil spill
5. Researchers find gene responsible for neurodegenerative disease in dogs, possibly in humans
6. Researchers study cinnamon extracts
7. K-state researchers explore physiological effects of space travel with NASA grant
8. Researchers connect APC protein to autism and mental retardation
9. MIT researchers develop a better way to grow stem cells
10. U of M researchers identify 2 FDA approved drugs that may fight HIV
11. Researchers advance understanding of enzyme that regulates DNA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOGĀ“s multi-biometrics system.   ... ...
(Date:3/16/2017)... HANOVER, Germany , March 16, 2017 CeBIT 2017 - Against ... Continue Reading ... Used combined in one project, multi-biometric solutions ... ... Identification Systems) ...
(Date:3/9/2017)... , March 9, 2017 4Dx has ... World Lung Imaging Workshop at the University of Pennsylvania. ... invited to deliver the latest data to world leaders ... event brings together leaders at the forefront of the ... lung imaging. "The quality of the ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... ... March 28, 2017 , ... ... with the American Association for the Advancement of Science (AAAS), the world's ... partnership, ReadCube will enhance its high-impact scholarly collection across its cross-platform reference ...
(Date:3/28/2017)... ... March 28, 2017 , ... Benchworks announced that ... Philadelphia. The event was offered by the Chamber of Commerce for Greater Philadelphia ... groups and interaction with speakers who are leaders in their industries. Topics included ...
(Date:3/28/2017)... WASHINGTON , March 28, 2017  (AACR17, ... single-cell sequencing during the American Association for Cancer Research ... Center in Washington, D.C. , April ... gene expression of thousands of cells at the individual ... Experts on-hand at AACR to discuss expanded ...
(Date:3/28/2017)... , March 28, 2017 Dr. ... life sciences corporation Anpac Bio-Medical Science Company ... new, international record, processing and reporting over 40,000 ... Differentiation Analysis" (CDA) liquid biopsy tests. ... Prize Laureate Summit publications, Anpac Bio,s CDA medical ...
Breaking Biology Technology: