Navigation Links
Research team wins funds to unravel a DNA mystery
Date:4/22/2009

An international research team headed by two researchers from the University of Adelaide, Australia, has been awarded a US$900,000 grant to help unravel the phenomenon of "DNA looping".

DNA looping is responsible for controlling the expression of genes in cells. It is believed to play a key role in a number of diseases, including many cancers.

The looping occurs due to the binding of proteins to different regions of the DNA. These proteins interact with each other so that the DNA loops in between them.

The funding, from the Human Frontier Science Program based in France, has been awarded to Dr Keith Shearwin and Dr Ian Dodd in the University's School of Molecular and Biomedical Science.

Their research aims to discover how the correct DNA loops are formed to ensure that the right gene is turned on at the right time and place.

This will be done by comparing DNA looping inside the cell with looping in the test tube and with predictions obtained through computer simulation.

Dr Shearwin and Dr Dodd will be designing the DNA sequences that will be used for the project and will be testing DNA looping inside the cell.

"It is basic research which underpins applied science. Understanding how genes are controlled has huge implications for health and for anything that depends on biology, not only for humans but also all sorts of organisms," Dr Dodd said.

"There are some diseases known which seem to be caused by incorrect looping interactions and improper control of gene interactions including some cancers," Dr Shearwin said.

"Anything we can do to help explain the processes involved could go some way towards helping future research into cancer and other diseases, which is why this basic research has attracted international interest and funding."

Dr Shearwin is a lecturer in biochemistry, with his main research areas being the control of gene expression and the processes involved in genetic development.

Dr Dodd, who has been awarded the William Elliott Biochemistry Research Fellowship, carries out research in molecular biology with a strong interest in using mathematical models to understand complex systems.

Dr Shearwin and Dr Dodd will be working with two teams from Atlanta and Pittsburgh over the next three years.


'/>"/>

Contact: Dr. Keith Shearwin
keith.shearwin@adelaide.edu.au
61-883-035-361
University of Adelaide
Source:Eurekalert

Related biology news :

1. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
2. LSUHSC student awarded top national honor for diabetes research
3. International honor for University of East Anglia ocean researcher
4. UT Southwestern researchers probe kidney damage, protection in lupus
5. Innerscope Research(R) Receives Three Great Minds Innovation Awards from the Advertising Research Foundation
6. Concordia University receives more than $22 million for genomics research
7. Researchers use brain interface to post to Twitter
8. Research suggests vegetable juice may help people with metabolic syndrome lose weight
9. Male flower parts responsible for potent grapevine perfume: UBC research
10. TGen researchers discover possible way to block the spread of deadly brain tumors
11. Burnham researchers present at 100th AACR Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2017)... -- At this year,s CeBIT Chancellor Dr. Angela Merkel ... Chancellor came to the DERMALOG stand together with the Japanese Prime Minster ... country. At the largest German biometrics company the two government leaders could ... recognition as well as DERMALOG´s multi-biometrics system.   ... ...
(Date:3/13/2017)... Future of security: Biometric Face Matching software  Continue ... ... to match face pictures against each other or against large databases. The recognition ... ... software for biometric Face Matching on the market. The speed is at 100 ...
(Date:3/7/2017)... March 7, 2017 Brandwatch , the leading social ... The Prince,s Trust to uncover insights to support its reporting, ... The UK,s leading youth charity will be using Brandwatch ... and get a better understanding of the topics and issues that ... ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... ... 2017 , ... Mass spectrometry is becoming more widely for clinical testing and ... its potential to perform challenging analyses in complex matrices and sample types. While mass ... for it to be routinely used for medical testing. , In this ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... ... time members of the Modular Building Institute (MBI), an international modular trade organization, ... the permanent modular category for the Pagliuca Life Lab at Harvard University. The ...
(Date:3/28/2017)... 2017  The National Pharmaceutical Council (NPC) today announced ... research organization as its newest member. David Cox ... North America ), will serve as his ... "We,re pleased to have Ipsen and Dr. Cox join ... . "We welcome their insights in helping us identify ...
(Date:3/28/2017)... ... 2017 , ... LabKey and collaborator Just Biotherapeutics, Inc. (Just) ... LabKey Biologics . Built in collaboration with Just and designed with input from ... research teams tools for biological entity registration, assay data integration, and workflow management ...
Breaking Biology Technology: