Navigation Links
Research team wins funds to unravel a DNA mystery
Date:4/22/2009

An international research team headed by two researchers from the University of Adelaide, Australia, has been awarded a US$900,000 grant to help unravel the phenomenon of "DNA looping".

DNA looping is responsible for controlling the expression of genes in cells. It is believed to play a key role in a number of diseases, including many cancers.

The looping occurs due to the binding of proteins to different regions of the DNA. These proteins interact with each other so that the DNA loops in between them.

The funding, from the Human Frontier Science Program based in France, has been awarded to Dr Keith Shearwin and Dr Ian Dodd in the University's School of Molecular and Biomedical Science.

Their research aims to discover how the correct DNA loops are formed to ensure that the right gene is turned on at the right time and place.

This will be done by comparing DNA looping inside the cell with looping in the test tube and with predictions obtained through computer simulation.

Dr Shearwin and Dr Dodd will be designing the DNA sequences that will be used for the project and will be testing DNA looping inside the cell.

"It is basic research which underpins applied science. Understanding how genes are controlled has huge implications for health and for anything that depends on biology, not only for humans but also all sorts of organisms," Dr Dodd said.

"There are some diseases known which seem to be caused by incorrect looping interactions and improper control of gene interactions including some cancers," Dr Shearwin said.

"Anything we can do to help explain the processes involved could go some way towards helping future research into cancer and other diseases, which is why this basic research has attracted international interest and funding."

Dr Shearwin is a lecturer in biochemistry, with his main research areas being the control of gene expression and the processes involved in genetic development.

Dr Dodd, who has been awarded the William Elliott Biochemistry Research Fellowship, carries out research in molecular biology with a strong interest in using mathematical models to understand complex systems.

Dr Shearwin and Dr Dodd will be working with two teams from Atlanta and Pittsburgh over the next three years.


'/>"/>

Contact: Dr. Keith Shearwin
keith.shearwin@adelaide.edu.au
61-883-035-361
University of Adelaide
Source:Eurekalert

Related biology news :

1. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
2. LSUHSC student awarded top national honor for diabetes research
3. International honor for University of East Anglia ocean researcher
4. UT Southwestern researchers probe kidney damage, protection in lupus
5. Innerscope Research(R) Receives Three Great Minds Innovation Awards from the Advertising Research Foundation
6. Concordia University receives more than $22 million for genomics research
7. Researchers use brain interface to post to Twitter
8. Research suggests vegetable juice may help people with metabolic syndrome lose weight
9. Male flower parts responsible for potent grapevine perfume: UBC research
10. TGen researchers discover possible way to block the spread of deadly brain tumors
11. Burnham researchers present at 100th AACR Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/5/2017)... LONDON , April 4, 2017 KEY ... is anticipated to expand at a CAGR of 25.76% ... neurodegenerative diseases is the primary factor for the growth ... full report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The ... of product, technology, application, and geography. The stem cell ...
(Date:3/30/2017)... 30, 2017 Trends, opportunities and forecast in ... by technology (fingerprint, AFIS, iris recognition, facial recognition, hand ... by end use industry (government and law enforcement, commercial ... banking, and others), and by region ( North ... Asia Pacific , and the Rest of ...
(Date:3/24/2017)... Research and Markets has announced the addition ... Trends - Industry Forecast to 2025" report to their offering. ... The Global Biometric ... of around 15.1% over the next decade to reach approximately $1,580 ... market estimates and forecasts for all the given segments on global ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... 2017 , ... A new study published in Fertility and ... in vitro fertilization (IVF) transfer cycles. The multi-center matched cohort study ... comparing the results from the fresh and frozen transfer cohorts, the authors of ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... conjugate (ADC) therapeutics, today confirmed licensing rights that give it exclusive global ... technology developed in collaboration with Children’s Hospital Los Angeles (CHLA). Additionally, ...
(Date:10/10/2017)... firm Parks Associates announced today that Tom Kerber , ... Meeting , October 11 in Scottsdale, Arizona . Kerber ... smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and the introduction ...
(Date:10/10/2017)... ... October 10, 2017 , ... The ... prestigious awards honoring scientists who have made outstanding contributions to analytical ... during Pittcon 2018, the world’s leading conference and exposition for laboratory science, which ...
Breaking Biology Technology: