Navigation Links
Research team shows how bacterial community evolves to survive
Date:5/12/2010

CINCINNATIAn international team led by a University of Cincinnati (UC) researcher has shown how a bacterial community evolves to survive hostile host defenses in the body.

The team, led by Malak Kotb, PhD, chair of UC's of molecular genetics, biochemistry and microbiology department, analyzed the evolution over time of the community structure of Group A streptococcus (also known as GAS or Strep A), a bacterium often found in the throat or on the skin. It can cause many human diseases, ranging from strep throat to debilitating and often deadly diseases of the heart, skin, kidney and brain.

In the 1980s, hypervirulent strains of the Strep A bacteria emerged, including necrotizing fasciitis (commonly known as the flesh-eating disease), an invasive GAS that is an infection of the deeper layers of skin and subcutaneous tissue. About 9,000 to 11,500 cases of invasive GAS diseasein which bacteria get into parts of the body where bacteria usually are not foundoccur each year in the United States, resulting in 1,000 to 1,800 deaths annually, according to the Centers for Disease Control and Prevention (CDC). In Greater Cincinnati, there have been several highly publicized cases associated with death or amputation.

The research team's findings appear in PLoS ONE, an open-access online journal of peer-reviewed articles.

"This is the first organized attempt to capture the dynamics of bacterial evolution in live species and to discover molecular events that are associated with stark changes in the demographics of the bacterial community as they sacrifice the majority of their members and select the fittest ones to survive host defenses," says Kotb, who is also director of the Midwest Center for Emerging Infectious Diseases (MI-CEID).

Researchers found that as dominant members of the population surrendered to host immune defenses, they were replaced by a hyperaggressive, mutant minority population that thrived and took over the abandoned comm
'/>"/>

Contact: Keith Herrell
keith.herrell@uc.edu
513-558-4559
University of Cincinnati Academic Health Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biofuel chemistry more complex than petroleum, say Sandia and Lawrence Livermore researchers
2. Researchers share insights into RNA
3. UT Southwestern researchers find mechanism that may stop E. coli from developing in cattle
4. A new effective strategy for treating tobacco addiction was developed by researchers from the CAS
5. Researchers offer first proof that chemicals from seaweeds damage coral on contact
6. UNC researchers receive $100,000 Grand Challenges Exploration Grant to develop male contraceptive
7. As monarch butterflies journey north, gardeners can help protect species, researcher says
8. Rensselaer researchers to send bacteria into orbit aboard space shuttle Atlantis
9. Researchers discover metabolic vulnerability in TB and potential drug target
10. ESCEO-IOF-ABBH Young Investigator Awards recognize research excellence
11. Researchers use entire islands in the Bahamas to test survival of the fittest
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/2/2015)... April 2, 2015 According to ... attributed to somewhat higher than 125 MSEK. This exceeds ... report 2014 that revenues for Q1 2015 would be ... reported for Q4 2014. The operating result for the ... The complete interim report will as previously communicated be ...
(Date:4/1/2015)... BOSTON , April 1, 2015   Medisafe ... 1.5 million users across iOS and ... has begun integrating biofeedback into the platform to allow ... health outcomes. For the first time, patients will be ... missing a dose impacts important biometrics, such as glucose ...
(Date:3/30/2015)... , Mar. 26, 2015 Research and Markets ... of the "Global Gesture Recognition Market in Automotive ... The analysts forecast the Global Gesture Recognition market in ... over the period 2013-2018. Gesture recognition is ... to different gestures of an individual. Gesture recognition technology ...
Breaking Biology News(10 mins):Fingerprint Cards Revises Revenues for Q1 2015 2Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2
... American Pregnancy Association, six million women a year deal with ... hope to women who want to conceive ― in the ... shelves right now. Prof. Adrian Shulman of Tel Aviv ... has found a statistical connection between the over-the-counter vitamin supplement ...
... at the Living Planet Symposium have been hearing about ... almost three months, the satellite is in excellent health ... presented at the symposium. Prof. Duncan Wingham, Lead ... in very good shape exceeding in-orbit specifications, the ...
... study of the occurrence of fishes in the ocean,s deepest ... species of fishes are more numerous at such depths than ... published in the July/August issue of BioScience , observed ... meters around a baited video lander in the Japan Trench. ...
Cached Biology News:Increasing fertility threefold 2CryoSat-2 exceeding expectations 2Study suggests more fish than thought may thrive in the ocean's depths 2
(Date:4/30/2015)... - Continued Advancement Toward Goal of ... Shire (LSE: SHP, NASDAQ: SHPG ) announces ... 2015. Financial Highlights Q1 2015 Growth(1) ... $1,488 million +11% +15% Non GAAP operating income $683 ... operations $475 million +55% Non GAAP EBITDA margin (excluding ...
(Date:4/30/2015)... 2015 Available in select spas ... , Phytomer’s DOUCEUR INTEMPORELLE Restorative Shield Cream ... while battling the weakening threat of inflammaging, aging ... formulated with star ingredient GLYCOSEA, a complex of ... complex of soothing minerals and trace elements. GLYCOSEA ...
(Date:4/30/2015)... Sterlitech is proud to offer Synder ... PY, and PZ Polyacrylonotrile (PAN) membranes , as ... to be ideal for oil removal in wastewater ... process requirements where the presence of oils in ... on industrial wastewater discharge and quality requirements for ...
(Date:4/29/2015)... 29, 2015 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the Company") today ... 2014. Biorem,s complete fiscal 2014 year-end financial statements and MD&A have been ... , 2013 , 2014 , 2013 Revenue ... 19,596 Gross profit 1,326 , 1,703 , 2,231 ... 1,493 , 3,377 , 4,562 Ebitda* 92 ...
Breaking Biology Technology:Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 2Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 3Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 4Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 5Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 6Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 7Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 8Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 9Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 10Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 11Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 12Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 13Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 14Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 15Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 16Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 17Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 18Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 19Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 20Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 21Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 22Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 23Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 24Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 25Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 26Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 27Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 28Shire Delivers Strong Revenue Growth and Cash Generation; 20% Increase in Non GAAP Earnings per ADS 29Phytomer introduces DOUCEUR INTEMPORELLE Restorative Shield Cream 2Phytomer introduces DOUCEUR INTEMPORELLE Restorative Shield Cream 3Sterlitech Offers New Ultrafiltration Membranes 2Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 2Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 3Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 4
... applications for the real world, has formalized ... Inc. One of the many businesses that ... Tier 1 automotive supplier focusing on technology-rich ... and Lumidigm will bring patented biometric functionality ...
... N.J., Aug. 5 Ortho Biotech is announcing,that it is voluntarily ... cracks in the necks of a,small number of vials upon post-manufacturing ... Approximately 44,292 vials of lot,P114942A in the following packaging configurations were ... NDC ...
... Replidyne, Inc.,(Nasdaq: RDYN ) today announced its financial ... 2008., Replidyne reported a net loss of $18.7 million ... per basic and diluted common share of $0.69,per share, compared ... share or $1.65 per common share on a fully diluted ...
Cached Biology Technology: Lumidigm Signs Strategic Agreement with Methode Electronics : Automotive Supplier Invests in Biometric Component Development 2Ortho Biotech Announces Nationwide Voluntary Recall of Procrit(R) (Epoetin Alfa) Lot Number P114942A 2Replidyne Announces Second Quarter 2008 Results From Operations 2Replidyne Announces Second Quarter 2008 Results From Operations 3Replidyne Announces Second Quarter 2008 Results From Operations 4Replidyne Announces Second Quarter 2008 Results From Operations 5Replidyne Announces Second Quarter 2008 Results From Operations 6Replidyne Announces Second Quarter 2008 Results From Operations 7
...
Use as the souce of CETP enzyme for screening CETP inhibitors. Use in conjunction with the CETP activity assay kit (K601-100)....
For mRNA Differential Display with three one-base anchored oligo-dT primers and rationally designed arbitrary 13mers. These kits feature the latest generation of isotopic mRNA Differential Display t...
22 x 50 mm; No. 1 thickness range: 0.13 to 0.17 mm, suitable for work in histology, cytology, urinalysis and microbiology, precleaned, store at room temperature ...
Biology Products: