Navigation Links
Research team finds important role for junk DNA
Date:5/20/2009

Scientists have called it "junk DNA." They have long been perplexed by these extensive strands of genetic material that dominate the genome but seem to lack specific functions. Why would nature force the genome to carry so much excess baggage?

Now researchers from Princeton University and Indiana University who have been studying the genome of a pond organism have found that junk DNA may not be so junky after all. They have discovered that DNA sequences from regions of what had been viewed as the "dispensable genome" are actually performing functions that are central for the organism. They have concluded that the genes spur an almost acrobatic rearrangement of the entire genome that is necessary for the organism to grow.

It all happens very quickly. Genes called transposons in the single-celled pond-dwelling organism Oxytricha produce cell proteins known as transposases. During development, the transposons appear to first influence hundreds of thousands of DNA pieces to regroup. Then, when no longer needed, the organism cleverly erases the transposases from its genetic material, paring its genome to a slim 5 percent of its original load.

"The transposons actually perform a central role for the cell," said Laura Landweber, a professor of ecology and evolutionary biology at Princeton and an author of the study. "They stitch together the genes in working form." The work appeared in the May 15 edition of Science.

In order to prove that the transposons have this reassembly function, the scientists disabled several thousand of these genes in some Oxytricha. The organisms with the altered DNA, they found, failed to develop properly.

Other authors from Princeton's Department of Ecology and Evolutionary Biology include: postdoctoral fellows Mariusz Nowacki and Brian Higgins; 2006 alumna Genevieve Maquilan; and graduate student Estienne Swart. Former Princeton postdoctoral fellow Thomas Doak, now of Indiana Univer
'/>"/>

Contact: Kitta MacPherson
kittamac@princeton.edu
609-258-5729
Princeton University
Source:Eurekalert

Page: 1 2

Related biology news :

1. URI receives $18 million grant to strengthen biomedical research capacity in Rhode Island
2. ISU researcher identifies genetic pathway responsible for much of plant growth
3. MCG researcher among first to receive NIH stimulus funding
4. Komodo even more deadly than thought: Research
5. UCSD researchers make first direct observations of biological particles in high-altitude ice clouds
6. Vitamin D expert receives Linus Pauling Prize for Health Research
7. BIO 2009 -- R&D session: New stem cell research unlocks unknown therapies
8. 3-D kidney atlas created for researchers and physicians
9. Researchers gain genome-wide insights into patterns of the worlds human population structures
10. Development of an artificial simulator of the nervous system to do research into diseases
11. UCI awarded $45 million for infectious disease research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) ... Monitor: North America Perimeter Security Systems Market" report ... The North American perimeter security market ... from 2014 to 2019. Although the U.S. market holds ... is expected to grow at a higher ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB ... Good Clinical Practices (GCP) audit to confirm its ... (FDA) regulations. This accomplishment enables HITLAB to conduct ... utilizing the highest principles for patient safety and ... improve global healthcare access, quality, and delivery with ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has ... in the APAC Region 2015-2019"  report to their ... in this market is advances in technology. With ... upgrade biometric solutions to the latest standard that ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... St. Louis, MO, USA, February 1, 2009 A ... Journal of the American Dietetic Association presents ... Assessment Study (SNDA-III), conducted by Mathematica Policy Research, Inc., ... data. Sponsored by the Food and Nutrition Service of ...
... New Orleans, LA Huijing Xia, PhD, a postdoctoral ... Assistant Professor of Pharmacology at LSU Health Sciences Center ... reporting that a recently identified enzyme in the brain ... of blood pressure. The LSUHSC research team showed that ...
... Sports Technology , published by Wiley-Blackwell, spotlights ... between able-bodied athletes and para-athletes, with two published ... entitled "Biomechanics of double transtibial amputee sprinting using ... the sprinting mechanics data of able-bodied sprinters with ...
Cached Biology News:Results of the third school nutrition dietary assessment study published 2Results of the third school nutrition dietary assessment study published 3Results of the third school nutrition dietary assessment study published 4LSUSHC researchers find potential new target for hypertension treatment 2
(Date:12/24/2014)... , Dec. 24, 2014   BioLife Solutions , ... manufacturer and marketer of proprietary clinical grade hypothermic ... precision thermal shipping products for cells and ... will hold its 2015 Annual Meeting of Stockholders on ... the expected date for the Annual Meeting represents a ...
(Date:12/24/2014)... MA (PRWEB) December 23, 2014 Earlier ... Dr. James L. Sherley, director of the Adult Stem ... on an often overlooked and under appreciated unique property ... Self-Renewal by Distributed Stem Cells: Misunderstood in the Past, ... message to congress participants. He gave the address ...
(Date:12/24/2014)... 23, 2014 According to Ross Selinger, President ... of ITRA Global, the national office market continues to be ... This is evidenced by the third quarter’s surprising 3.9% GDP, ... Low energy costs have held inflation down and the Fed ... the housing market remaining soft. , This solid economic news ...
(Date:12/24/2014)... report expects global cell isolation and expansion market to ... carefully analyzed data about the vital drivers, restraints, trends, ... Copy of Report @ http://bit.ly/1yUxy0T , According ... will keep witnessing growth at an impressive CAGR during ... by rapid technological advancements, government funding and investments, and ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3
... press release is available in German . ... be no longer useless or even a problem. On the ... easily or to store data more efficiently! These are two ... made at the Physikalisch-Technische Bundesanstalt (PTB). This so-called "thermoelectric voltage" ...
... 2011 Pacira Pharmaceuticals, Inc. (Nasdaq: PCRX ), ... for the company,s third quarter ended September 30, 2011 will ... 2011. The Pacira management team will host a conference call ... developments on Monday, Oct. 31, 2011 at 9 a.m. ET. ...
... Mexico, Oct. 24, 2011 Synthetic Genomics Inc. (SGI), ... solutions to a variety of markets including biofuels, biochemicals, ... C.V., a Mexico based investing and management company with ... agribusiness, have announced the formation of a new company, ...
Cached Biology Technology:Magnetic nanoswitch for thermoelectric voltages 2Pacira Pharmaceuticals, Inc. Announces Timing for Third Quarter 2011 Financial Results Webcast and Conference Call 2Pacira Pharmaceuticals, Inc. Announces Timing for Third Quarter 2011 Financial Results Webcast and Conference Call 3Synthetic Genomics Inc. and Plenus, S.A. de C.V. Form New Sustainable Agriculture Company, Agradis, Inc. to Develop and Commercialize Products Using Genomic Technologies 2Synthetic Genomics Inc. and Plenus, S.A. de C.V. Form New Sustainable Agriculture Company, Agradis, Inc. to Develop and Commercialize Products Using Genomic Technologies 3Synthetic Genomics Inc. and Plenus, S.A. de C.V. Form New Sustainable Agriculture Company, Agradis, Inc. to Develop and Commercialize Products Using Genomic Technologies 4Synthetic Genomics Inc. and Plenus, S.A. de C.V. Form New Sustainable Agriculture Company, Agradis, Inc. to Develop and Commercialize Products Using Genomic Technologies 5
... suitable for use with a wide range ... to water and some of the higher ... of removing water and organic solvents from ... microplates, vials and round bottom flasks; making ...
... The Brownlee Precision Model 410 is a ... used to amplify small signals from sources which ... frequency noise. Each channel consists of a high ... 2-pole lowpass filter, and an output offset control. ...
Proliferin (N-14)...
Porcine Aortic Smooth Muscle Cells (PAOSMC) (>500,000 cells)...
Biology Products: