Navigation Links
Research reveals first glimpse of brain circuit that helps experience to shape perception
Date:3/2/2014

Cold Spring Harbor, NY Odors have a way of connecting us with moments buried deep in our past. Maybe it is a whiff of your grandmother's perfume that transports you back decades. With that single breath, you are suddenly in her living room, listening as the adults banter about politics. The experiences that we accumulate throughout life build expectations that are associated with different scents. These expectations are known to influence how the brain uses and stores sensory information. But researchers have long wondered how the process works in reverse: how do our memories shape the way sensory information is collected?

In work published today in Nature Neuroscience, scientists from Cold Spring Harbor Laboratory (CSHL) demonstrate for the first time a way to observe this process in awake animals. The team, led by Assistant Professor Stephen Shea, was able to measure the activity of a group of inhibitory neurons that links the odor-sensing area of the brain with brain areas responsible for thought and cognition. This connection provides feedback so that memories and experiences can alter the way smells are interpreted.

The inhibitory neurons that forge the link are known as granule cells. They are found in the core of the olfactory bulb, the area of the mouse brain responsible for receiving odor information from the nose. Granule cells in the olfactory bulb receive inputs from areas deep within the brain involved in memory formation and cognition. Despite their importance, it has been almost impossible to collect information about how granule cells function. They are extremely small and, in the past, scientists have only been able to measure their activity in anesthetized animals. But the animal must be awake and conscious in order to for experiences to alter sensory interpretation. Shea worked with lead authors on the study, Brittany Cazakoff, graduate student in CSHL's Watson School of Biological Sciences, and Billy Lau, PhD a p
'/>"/>

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tackling tumors with space station research
2. First-of-its-kind web portal to bolster research and treatment for rare diseases
3. Researchers reveal the dual role of brain glycogen
4. Montreal researchers find a link between pollutants and certain complications of obesity
5. CNIO researchers discover new strategies for the treatment of psoriasis
6. Researchers trap moths with plant-produced sex pheromone
7. New research indicates causal link between vitamin D, serotonin synthesis and autism
8. 3D microgels on-demand offer new potential for cell research
9. Research: Fructose not responsible for increase in non-alcoholic fatty liver disease
10. Dartmouth-led research shows temperature, not snowfall, driving tropical glacier size
11. Researchers generate new neurons in brains, spinal cords of living adult mammals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... link between autism and disrupted brain development is ... disease, and is largely unknown. However, thanks to ... (SFARI), George Washington University (GW) researcher Anthony-Samuel LaMantia, ... and in-depth answers to these key questions in ... professor of pharmacology and physiology at the GW ...
(Date:7/25/2014)... in the International Journal of Cancer earlier ... cancer based on findings showing successful reduction in the ... population of cells in the cervix. , The ... junction cells, or SCJ cells. These cells reside in ... origins of cervical cancer. A research team co-led by ...
(Date:7/25/2014)... 600 scientists from 25 countries and 35 states ... by the Genetics Society of America (GSA) next ... The conference will feature close to 500 presentations ... topics including gene expression and regulation, functional genomics, ... aging, and a variety of diseases. , ...
Breaking Biology News(10 mins):GW researcher receives grant to answer the how and why of autism during development 2Clearing cells to prevent cervical cancer 2Yeast meeting to showcase latest breakthroughs in genetics and molecular biology 2
... known as the winter vomiting bug, is one of the ... highly contagious, causing vomiting and diarrhea, and the number of ... have to let the virus run its course for a ... associated with outbreaks of hNoV but it remains difficult to ...
... home to countless microorganisms that we can,t see, but these ... known as the skin microbiome - contribute to our health ... from pathogens, and mediating skin disorders. In a new study, ... in a contact sport, using roller derby as their model ...
... French . Researchers at the University of Montreal,s ... new mechanism that allows some cells in our body to move ... soldiers depicted in the Asterix series. Collective cell migration is an ... is also used by cancerous cells to disseminate efficiently in the ...
Cached Biology News:What impact does a day of roller derby have on our skin microbiome? 2Asterix's Roman foes -- Researchers have a better idea of how cancer cells move and grow 2
(Date:7/24/2014)... 2014 WIRB-Copernicus Group ® ("WCG")™, ... review services for clinical research, announced today that ... of Richmond, VA -based Alliance ... biosecurity consulting firm in the United ... division – WCG Biosafety™ – will be able ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 The first ... Dose Escalation in First in Human Studies” will cover ... better go/no-go decisions. , With increasing R&D costs and ... companies need to maximize the knowledge collected in early ... and improve success in late stage development. , Next, ...
(Date:7/24/2014)...  Spherix Incorporated (SPEX) -- an intellectual property development ... property, today announced that the Company will issue a ... on Monday, August 18, 2014 for shareholders. Management has ... Monday, August 18, 2014 to discuss the company,s progress ... Anthony Hayes . Following prepared remarks, ...
(Date:7/24/2014)... 24, 2014 As part of the ... in the MENA region during 2014 with potential global ... provider agreement with DZS to manage our clinical trials ... Global VP of R&D and President of SBI pharmaceuticals ... operational practices with a focus on utilizing eClinical software ...
Breaking Biology Technology:WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3Best Practices for Optimizing Dose Escalation in First in Human Studies, New Webinar August 6th Hosted by Xtalks 2Spherix Schedules Shareholder Update Call 2SBI Pharmaceuticals Co. Ltd. Enters into Preferred Provider Agreement with DZS Clinical Services 2
... contact the Communications and External Relations staff member identified at ... and its research and development activities, please refer to one ... question or comment, you can send it to news@ornl.gov ... . Nanoscale robots that can flow through blood ...
... July 13, 2011 Emerson Ecologics, LLC, the ... healthcare practitioner market, today announced that the company ... national distributor for their full product line of ... focused on reversing chronic illness and improving health ...
... July 13, 2011 Reportlinker.com announces that ... in its catalogue: Industrial ... http://www.reportlinker.com/p0570053/Industrial-Biotechnology-China-News-1106.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Renewable_energy In this ... policy and regulation about biofuel, which include ...
Cached Biology Technology:Story tips from the Department of Energy's Oak Ridge National Laboratory, July 2011 2Story tips from the Department of Energy's Oak Ridge National Laboratory, July 2011 3Story tips from the Department of Energy's Oak Ridge National Laboratory, July 2011 4Emerson Ecologics Expands Partnership With Metagenics, Announces National Distribution Agreement 2Emerson Ecologics Expands Partnership With Metagenics, Announces National Distribution Agreement 3Industrial Biotechnology China News 1106 2Industrial Biotechnology China News 1106 3Industrial Biotechnology China News 1106 4
Antibodies were affinity purified using epitopes specific to UBAP2L/NICE4 immobilized on solid support....
UltraPure DNase/RNase-Free Distilled Water is designed for use in all molecular biology applications. It is 0.1-m membrane-filtered and tested for DNase and RNase activity....
...
Water Distilled (Gibco™) is membrane filtered and endotoxin screened....
Biology Products: