Navigation Links
Research offers means to detoxify mycotoxin-contaminated grain intended for ethanol, animal feed
Date:9/12/2011

l environmental sciences, has been collaborating with Kevin Hicks, team leader, and John Nghiem, chemical engineer, at the USDA Agricultural Research Service Sustainable Biofuels research team in Wyndmoor, Pa. a partnership that began in 2001.

The Virginia Tech and USDA researchers decided to go after the most common mycotoxin in barley, deoxynivalenol (DON).

Previous research on a fungus (Fusarium graminearum) that produces DON in barley has identified several genes that convert trichothecenes to less toxic products. The research team selected two of these genes (TRI101 and TRI201), introduced them into a laboratory yeast strain (RW2802), and compared the results to commercial yeast that has been optimized to produce fuel ethanol. The researchers fermented four varieties of barley that Griffey's team created for biofuel use, hulless Eve and VA06H-25 and hulled Thoroughbred and Price.

Measurements of the resulting mash and animal feed revealed that DON had indeed been converted to a less toxic form (3ADON) during fermentation, with the transgenic yeast expressing either TRI101 or TRI201. The researchers wrote, "We found large reductions in DON via conversion (52.4 percent to 58.1 percent) during fermentation of the hulless barley line VA06H-25, which contained the highest levels of DON in its starting ground grain."

"But in all cases, using the yeast with the added genes resulted in decreased DON as it was converted to the less toxic form (3ADON)," said Khatibi.

"To our knowledge, this is the first detailed report of yeast expressing a DON modification enzyme during barley ethanol fermentation," said Schmale.

Khatibi said, "This study sets the foundation for modifying mycotoxins during fermentation and provides a model for future work when we find an enzyme that can actually destroy the toxin."

The research was supported by Schmale and Griffey's grants from the USDA, Virginia Agriculture Council, and M
'/>"/>

Contact: Susan Trulove
strulove@vt.edu
540-231-5646
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UT researcher investigates Deepwater Horizon oil spill impact on coast
2. UTHealth, BCM researchers find common gene variant associated with aortic dissection
3. Researchers find high levels of toxic PCBs in Indiana Harbor and Ship Canal
4. Louisville researcher awarded $12.8 million NIH grant renewal for adult stem cell project
5. $21.5 million for materials research at the University of Utah
6. UH researchers work to develop screening method for superbug
7. Researchers find hormone that predicts premature death in kidney patients
8. NSF establishes Triangle (NC) Center for Soft Matter Research
9. Scripps Research team overcomes major obstacle for stem cell therapies and research
10. Chinese researchers identify insect host species of a famous Tibetan medicinal fungus
11. Researchers publish study on neuronal RNA targeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... VIEW, Calif. , July 7, 2015 /PRNewswire/ ... biometrics market, Frost & Sullivan recognizes Credence ID, ... Sullivan Entrepreneurial Company of the Year Award. ... suite to aid in its mission of offering ... under-recognized populations globally. As Credence ID was formed ...
(Date:7/2/2015)... 2015 Research and ... the "Natural Language Processing Market by Type ... Pattern & Image Recognition) - Worldwide Forecast to ... The key vendors occupying the market are 3M, ... Corporation, NetBase Solutions, SAS Institute Inc., Verint Systems ...
(Date:7/2/2015)... Fingerprint Cards has received an order ... from the distributor World Peace Industrial Group (WPI), part of ... Asia . Deliveries are planned to take place ... by smartphone manufacturers in Asia . The ... revenue guidance of approximately 2,200 MSEK for 2015. ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... at Michigan State University have shown a prebiotic may ... infection and reduce inflammation, greatly decreasing the risk of ... as food for the trillions of tiny bacteria living ... growth of the "good" bacteria. The evolution of prebiotic ...
... presented at Europe,s leading breast cancer translational research conference ... differences between individual breast cancers. Focused on ... sensitive to important therapies, the new studies will help ... for millions of patients. "Despite major advances in ...
... of long-forgotten habitats and the resurgence of species unseen for ... natural disaster. Yet that,s exactly what researchers have found on ... earthquake and devastating tsunami in 2010. Their study also revealed ... a major symptom of climate change. In a ...
Cached Biology News:Researchers show prebiotic can reduce severity of colitis 2New data improve understanding of breast cancer's multiple varieties 2New data improve understanding of breast cancer's multiple varieties 3New data improve understanding of breast cancer's multiple varieties 4New data improve understanding of breast cancer's multiple varieties 5New data improve understanding of breast cancer's multiple varieties 6First-of-its-kind study reveals surprising ecological effects of earthquake and tsunami 2First-of-its-kind study reveals surprising ecological effects of earthquake and tsunami 3
(Date:7/27/2015)... July 27, 2015 The Brain ... winners of its annual Klerman and Freedman Prizes, ... who have been supported by NARSAD Young Investigator ... pursue innovative ideas in neurobiological and psychosocial research, ... for the early detection, treatment, prevention and cure ...
(Date:7/27/2015)... Maine , July 27, 2015 IDEXX ... more than 8,000 clinics have submitted over 100,000 specimens ... testing in just the first 10 days since the ... kidney disease (CKD) is a leading cause of suffering ... the submitted specimens are consistent with generally accepted kidney ...
(Date:7/26/2015)... ... July 26, 2015 , ... Maine ... calibration verification / linearity test kit. The VALIDATE® ANEMIA kit contains Ferritin, Folate, ... is prepared using the CLSI recommended “equal delta” method for linearity testing and ...
(Date:7/24/2015)... -- Ryan & Maniskas, LLP that a class ... for the Northern District of California ... common stock of Avalanche Biotechnologies, Inc. ("Avalanche" or the "Company") ... 15, 2015, inclusive (the "Class Period"). Avalanche shareholders ... for appointment as a lead plaintiff of the Class.  If ...
Breaking Biology Technology:Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 2Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 3Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 4Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 5Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 6Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 2Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 3Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 4Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 5Maine Standards Company, LLC Announces Release of VALIDATE® ANEMIA Calibration Verification / Linearity Test Kit 2Ryan & Maniskas, LLP Announces Class Action Lawsuit Against Avalanche Biotechnologies, Inc. 2Ryan & Maniskas, LLP Announces Class Action Lawsuit Against Avalanche Biotechnologies, Inc. 3
... Northwest,Biotherapeutics, Inc. (OTC Bulletin Board: NWBO; AIM: NWBT and ... and Promissory Note,(the "Note") with SDS Capital Group SPC, Ltd ... Note is an unsecured obligation of,the Company and accrues interest ... Note is six months, with a maturity date of April ...
... PARIS, Oct. 1 The 2008 Frost & ... of the Year,Award is presented to Biospace Lab ... product portfolio. The company,s outstanding,product line has allowed ... leading to increased market share., "An in-depth ...
... Horizon Therapeutics, Inc., a,privately held biopharmaceutical company, ... executive officer, will present a corporate,overview at the ... on,Tuesday, October 7 at 9 a.m. ET at ... Therapeutics, Horizon Therapeutics, Inc. is a late-stage ...
Cached Biology Technology:Northwest Secures US$1.0 Million Debt Financing 2Northwest Secures US$1.0 Million Debt Financing 3Northwest Secures US$1.0 Million Debt Financing 4Small Animal Imaging Market: Biospace Lab Wins Frost & Sullivan Accolade for Its Successful Product Line Strategy 2Small Animal Imaging Market: Biospace Lab Wins Frost & Sullivan Accolade for Its Successful Product Line Strategy 3Small Animal Imaging Market: Biospace Lab Wins Frost & Sullivan Accolade for Its Successful Product Line Strategy 4
... ion exchange media are rigid macroporous hydrophilic ... flow rates at moderate pressures, while the ... and the hydrophilic matrix reduces nonspecific binding. ... strong anion exchanger with very high flow ...
... collection of phage display libraries, human ... and mouse tissues. All cDNA libraries ... size of cDNA inserts has been ... 1000bp by gel electrophoresis of DNA ...
... IDS Corticosterone kit is a competitive enzymeimmunoassay ... in mouse or rat serum or plasma. ... corticosteroid in rats and mice, and in ... and reptiles. Most mammals produce both corticosterone ...
Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen ( Abpromise for all tested applications). Antigen: Purified F1 antigen of Y. pestis vaccine strain EB....
Biology Products: