Navigation Links
Research of zebrafish neurons may lead to understanding of birth defects like spina bifida
Date:2/18/2014

o genes in higher vertebrates including mammals.

Chandrasekhar's work contributes to a better understanding of how neuronal networks are organized and "wired" during development. These studies also may provide insight into birth defects like spina bifida, which affects 1 in every 2,000 births, according to the National Institutes of Health.

"One of the hallmarks of spina bifida is an open neural tube in the spinal cord," Chandrasekhar said. "The cells closing the neural tube actually know left from right, and front from back, just like the neurons migrating to their appointed places in the zebrafish hindbrain. Additionally, mutations in many genes that result in defective neuronal migration can lead to defects in neural tube closure. We anticipate that understanding the genes and mechanisms controlling neuronal migration in zebrafish will shed light on the mechanisms of human neural tube closure, and why this process goes awry in spina bifida."

Chandrasekhar's study, "Structural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafish" was recently published in February 2014 edition of Mechanisms of Development. He also published a related study, "The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function," in the October 2013 edition of Developmental Biology.


'/>"/>

Contact: Jeff Sossamon
573-882-3346
University of Missouri-Columbia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers propose a better way to make sense of Big Data
2. Research team establishes benchmark set of human genotypes for sequencing
3. Researchers shed new light on the genetic history of the European beaver
4. Two NYU faculty win Sloan Foundation research fellowships
5. Researchers identify new way to control stone fruit disease
6. Researchers warn against abrupt stop to geoengineering method
7. Researchers hijack cancer migration mechanism to move brain tumors
8. CU-Boulder stem cell research may point to new ways of mitigating muscle loss
9. MLB largely responsible for players steroid abuse, UTA researcher says
10. Hot issues in climate change research to be debated at AAAS Annual Meeting
11. Plastic shopping bags make a fine diesel fuel, researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research of zebrafish neurons may lead to understanding of birth defects like spina bifida
(Date:4/17/2015)... BURNABY, Canada , April 17, 2015 /PRNewswire/ ... projects, growing security concerns, and technological advancement to ... Arabia until 2020   ... " Saudi Arabia Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric ... is projected to register growth at CAGR ...
(Date:4/14/2015)... April 14, 2015  HYPR Corp. today announced ... ® ) Alliance tm , an industry consortium ... commit to share technology and collaborate to deliver ... interoperable, more secure and private, and easier to ... verification that protects sensitive user information and eliminates ...
(Date:4/14/2015)... April 14, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, announces ... the 2015 New York Design Awards under the category  ... York City Design Awards are part of a global ... 2,500 ratings from the marketplace, industry and judging panel. ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... Oncogenes are genes that when mutated or expressed in high ... from Tel Aviv University is demonstrating that Ras, one of ... well as harm. Ph.D. student Oded Rechavi and ... have found that Ras has the ability to transfer from ...
... Diabetes Research Foundation said today that for the fourth time ... a collaboration agreement with a large pharmaceutical company to move ... trials. According to JDRF, a leader in setting the ... and advocate of type 1 diabetes research, the development is ...
... The SIB Swiss Institute of Bioinformatics and the Biozentrum ... Computational Biology Conference "Molecular Evolution", opened today at the ... the 200th birthday of Charles Darwin and the 150th ... the Origin of the Species". Invited speakers include ...
Cached Biology News:Cancer-causing protein can also help fight the tumors it causes 2Another JDRF partner moves research forward with collaboration agreement for diabetes treatment 27th annual [BC]2 Basel Computational Biology Conference 'Molecular Evolution' June 18-19, 2009 27th annual [BC]2 Basel Computational Biology Conference 'Molecular Evolution' June 18-19, 2009 3
(Date:4/17/2015)... LC Sciences LLC, a leading developer ... it is seeking beta testers for the VariantPro™ ... targeted sequencing technology. The system offers cost-effective, minimal ... detection of rare variants. It utilizes novel and ... will collaborate with beta testers to generate test ...
(Date:4/16/2015)... Spirax Sarco, the leader in ... newly designed, state-of-the-art website in the first quarter ... promotes the Spirax Sarco brand, company capabilities, and ... a site visitor might be looking for including ... serviced, the latest company news, careers, and much ...
(Date:4/16/2015)... Mass. (PRWEB) April 16, 2015 ... smart data solutions driven by Semantic Web technology, ... of specialist information and services for the academic ... announced that its joint solution ‘Smart Data Lake ... a finalist for the 2015 Bio-IT ‘Best of ...
(Date:4/16/2015)... FL (PRWEB) April 16, 2015 ... cap distribution and physician network in Europe and ... company has appointed Fernando Bermúdez, former Business Development ... , An industry veteran, Mr. Bermúdez’s professional achievements ... 75% in Spain, while also penetrating the Portuguese ...
Breaking Biology Technology:LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 2LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 3Spirax Sarco website has a new look 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 3Capillus, LLC Extends Laser Hair Therapy Products to Europe and Asia 2
... CANTON, Mass., Aug. 18 Metabasis, a San Diego-based biotech ... equipment that is no longer essential to their ongoing operations. ... listed the premium lab and analytical equipment on the EquipNet ... , Metabasis is a biotech firm, specializing ...
... , , BOSTON, Aug. 18 ... Communications, is pleased to host their September Congress taking place at ... current economic climate, with heightened M & A activity in the ... and governance has become more critical," says Sharon Langan, Senior Program ...
... The University of Georgia Research Foundation, Inc. (UGARF) and ... non-exclusive license for a portfolio of glow-in-the-dark pigments that ... of the visible spectrum for nearly a day. ... Phosphorescence is a process in which energy ...
Cached Biology Technology:Massive Inventory of Premium Lab & Analytical Equipment Now Available 2CBI Hosts 5th Annual Pharma/Biotech Enterprise Governance, Risk and Controls Congress 2UGA, UPR grant license for long-persistence glow materials, in any color 2UGA, UPR grant license for long-persistence glow materials, in any color 3UGA, UPR grant license for long-persistence glow materials, in any color 4
... an endoribonuclease, the RNA strand of ... origin, e.g. that of phage FX174, ... x poly(dT). RNase H produces ribonucleotides ... no activity is detected with polyribonucleotides ...
... an overproducing clone of T4 DNA Ligase. Description: ... phosphodiester bond between juxtaposed 5' phosphoryl and ... repairs single-stranded nicks in duplex DNA, RNA or ... cohesive-end fragments of duplex DNA or RNA (1) ...
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
SHEEP ANTI BOVINE BETA-LACTOGLOBULIN A...
Biology Products: