Navigation Links
Research improves diagnosis and treatment of bleeding disorder
Date:2/16/2011

A rare bleeding disorder that can lead to life-threatening bleeding episodes is misdiagnosed in 15 per cent of cases according to findings from a new international research project led by a Queen's professor.

"Correct diagnosis is critical because it determines the treatment decision," says Maha Othman, a professor in the Department of Anatomy and Cell Biology who led the three-year research project on the rare platelet type of von Willebrand disease (VWD).

Patients with VWD are commonly treated with drugs that help control their condition. However, these drugs aggravate bleeding in patients with the rarer platelet form of the disease, and misdiagnosis can leave these patients vulnerable to severe life-threatening bleeding episodes in situations like pregnancy and surgical operations.

Although both forms of VWD are genetic disorders that share many diagnostic features, the defect actually lies in two different genes. A correct diagnosis can only be made by closely examining certain areas of both genes to determine where the defect lies.

Dr. Othman's study is the first large study to investigate the occurrence of the two types of VWD worldwide and to evaluate DNA analysis as a diagnostic tool.

In addition to pioneering this international project, Dr. Othman has also created an online registry aimed at determining the frequency of the rare platelet form of VWD and to collect data about the disorder. Despite its relative rarity, VWD is actually the most common genetically inherited bleeding disorder, affecting about one per cent of the general population.

Dr. Othman's research will be published in the March issue of the Thrombosis and Haemostasis Journal.


'/>"/>

Contact: Christina Archibald
christina.archibald@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert

Page: 1

Related biology news :

1. NIDCD research at ARO Midwinter Meeting
2. MU researchers believe discovery could lead to testing that displaces colonoscopies
3. Researchers link gene mutations to Ebsteins anomaly
4. Whitehead member Rudolf Jaenisch honored for groundbreaking stem cell research
5. UT researchers link algae to harmful estrogen-like compound in water
6. FASEB praises President Obama for increasing funding for research in his FY 2012 budget
7. Ben-Gurion U. researchers develop techniques to manipulate plant adaption in arid climates
8. Jefferson researchers provide genetic evidence that antioxidants can help treat cancer
9. Earliest humans not so different from us, research suggests
10. Researchers working toward automating sedation in intensive care units
11. U of Alberta researcher discovers potential cancer therapy target
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... 31, 2016  Genomics firm Nabsys has completed a ... Barrett Bready , M.D., who returned to the company ... technical leadership team, including Chief Technology Officer, John ... Steve Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys ...
(Date:3/21/2016)... 2016 Unique technology combines ... superior security   Xura, Inc. ... secure digital communications services, today announced it is working ... enterprise customers, particularly those in the Financial Services Sector, ... authentication within a mobile app, alongside, and in combination ...
(Date:3/14/2016)... 2016 NXTD ) ("NXT-ID" or the ... announces the airing of a new series of commercials on ... March 21 st .  The commercials will air on Bloomberg ... on the Street show. --> NXTD ) ("NXT-ID" ... commerce market, announces the airing of a new series of ...
Breaking Biology News(10 mins):
(Date:5/19/2016)... 19, 2016  AdvancedFlow Systems Inc. (AFS), a ... out of Maple Ridge, British Columbia ... its existing portfolio of contract manufacturing clients by ... with its sister companies Surround Technologies (STI) and ... industrial group that specializes in providing contract manufacturing ...
(Date:5/19/2016)... 19, 2016 - I dati ... durante il 52 ° Congresso ... - Le conclusioni dello studio indicano un ... trattati, di cui il 90% presenta una d urata ... più. Il settantadue per cento dei pazienti ha riscontrato un ...
(Date:5/18/2016)... ... , ... STACS DNA Inc., the sample tracking software company, today announced that ... processing to help them save time and reduce errors. , Sexual Assault kits are ... and victims informed of results. Due to a previous lack of tools, many forensic ...
(Date:5/17/2016)... 2016 Haselmeier announces the launch ... approval by EMA, the European Medicines Agency. Originally launched ... company, the new pen version includes enhancements to further ... confidence to patients during use. Its enhanced ... to handle with a larger display window that improves ...
Breaking Biology Technology: