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Research highlights from ICAAC meeting

cal application.

Symposium 132

New Treatment for Lung Infection

Treatment with interleukin-18 binding protein (IL-18BP) in a mouse model of Pseudomonas aeruginosa acute lung infection resulted in significantly increased survival, decreased lung injury and decreased weight loss. P. aeruginosa is a significant cause of lung infections in hospitalized and cystic fibrosis patients and one of its virulence factors is its ability to cause inflammation by inducing the immune system to secrete IL-18.

Emmanuel Faure, Lille 2 Teaching Hosp., Lille, France

Poster Session 143, Paper B-1055 (summary available)

ESBL Antibiotic Resistance in Netherlands

A large scale study of antibiotic resistance in the Netherlands finds approximately 7% of enterobacteriaceae harbored extended-spectrum betalactamase (ESBL), a slight increase relative to earlier studies. The good news is 95% of ESBLs were still suceptible to the antibiotic ertapenem and other alternate therapies.

Wouter van den Bijllaardt, St. Elisabeth Hosp., Tilburg, Netherlands

Poster Session 148, Paper C2-1116 (summary available)

Antibiotic Synergy Overcomes Multidrug Resistance

Synergistic or additive effects between the antibiotics tigecycline and colistin may be useful therapies against multidrug-resistant bacteria such as those carrying the plasmid for NDM-1.

Jonathan Betts, Queen Mary, Univ. of London, London, United Kingdom

Poster Session 152, Paper E-1157 (summary available)

New Compound Active Against Multiple STDs

An experiemental compound displays potent activity against a variety of bacterial pathogens that cause sexually transmitted diseases.

Susanne Paukner, Nabriva Therapeutics AG, Vienna, Austria

Poster Session 153, Paper E-1183 (summary available)

Can Vitamin D Prevent Ear Infections?

Children receiving vitamin D supplements are significantly less like to have recurring acute otitis medi

Contact: Garth Hogan
American Society for Microbiology

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