Shorter, Once-Daily Treatment Just as Effective
In a pivotal study of two antibiotic treatment regimens for acute skin and skin structure infections, once-daily treatment with the antibiotic tedizolid for 6 days was found to be as effective as twice-daily treatment with the antibiotic linezolid for 10 days.
Carisa De Anda, Trius Therapeutics, San Diego, CA, United States
Poster Session 21, Paper L-203
Single Dose Drug Candidate Equal to Week of Vancomycin
Phase III clinical results show that a single dose of the in-development drug oritavancin is just as effective as 7-10 days of vancomycin in adults with acute bacterial skin and skin structure infections requiring intravenous therapy.
Ralph Corey, Duke Clin. Res. Inst., Durham, NC, United States
Poster Session 21, Paper L-204 (summary available)
Breath Test for Fungal Disease
Researchers have identified specific volatile organic compounds found only in the breath of patients with the invasive fungal disease apergillosis, which could lead to the development of a diagnostic breath test for the disease.
Sophia Koo, Brigham & Women's Hosp., Boston, MA, United States
Poster Session 23, Paper M-219 (summary available)
Can Vitamins and Nutritional Supplements Prevent or Treat Disease?
There is much interest in the role of nutrients and micronutrients in the support of host defense against infections. However, there is controversy in the ability of supplements to help prevent or treat infections. This session sheds light on the intersection of human nutrition and infectious diseases. Presentations will focus on the role of vitamin D supplements on tuberculosis and the common cold, micronutrients in HIV and zinc therapy for infection in special populations.
Toxin Reduces Antibiotic Efficacy
Neutralization of the S. aureus alpha-toxin (AT) mak
|Contact: Garth Hogan|
American Society for Microbiology