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Research elucidates way lungs fight bacteria and prevent infection
Date:1/23/2009

thick and sticky, leaving the lung more prone to infection and inflammation, while still killing infection-causing bacteria.

The findings, in mice, demonstrate a way to inhibit proteases and restrict the junctions between cells in the airway mucosa, meaning that fewer white blood cells can get into the airway causing less inflammation.

Thus, epithelial proteases could be an important target to control inflammation in the lung, and could serve as the basis for the development of novel drugs to help the human body get the optimal number of white blood cells to an infection site without letting inflammation spiral out of control.


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Contact: Alex Lyda
mal2133@columbia.edu
212-305-0820
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

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