Navigation Links
Research breakthrough on the question of life expectancy
Date:8/5/2010

Why do we grow old and what can we do to stop it? This is the question asked by many, but it appears that we are now closer to an answer thanks to new research published by Monash University researcher Dr Damian Dowling.

According to the research published in the August edition of the prestigious journal, the American Naturalist, a small set of genes in mitochondria (a membrane-enclosed organelle found in most eukaryotic cells), passed only from mothers to offspring, plays a more dynamic role in predicting life expectancies than ever previously anticipated.

The research discovered that particular mitochondrial haplotypes were linked to the life expectancies of females in the beetle species Callosobruchus maculatus.

"What we found in these beetles that some combinations of mitochondrial and nuclear genomes confer long life in virgin females, but these are not the same combinations that result in long life in females that mate once, or in females that mate many times," Dr Dowling said.

"Clearly, the genetic determinants underlying life expectancies are complex.

"As we unravel this complexity, we draw closer to the day in which we might use the genetic information encoded in the mitochondria to assist in the development of therapies that slow the onset of ageing in humans," Dr Dowling said.

In animals, most of the genetic material that controls bodily functions is found inside the cell nucleus. This is the nuclear genome it is passed on from generation to generation through both mothers and fathers, and it encodes somewhere between 14 thousand and 40 thousand proteins.

However, a separate genome exists that is found only within the energy-producing factories of our cells the mitochondria. To put things in perspective, the mitochondrial genome is tiny, encoding just 13 proteins. Despite being so small, it can pack a punch when it comes to its ability to affect a range of fundamental biologi
'/>"/>

Contact: Megan Gidley
megan.gidley@monash.edu
61-039-903-4843
Monash University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Inc., the leading personal genetics company, today announced the publication ... of individuals from across the United States ... hundred years ago, the United States ... continents. This study illuminates how American history and the ongoing ...
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM announced ... audit to confirm its adherence to current U.S. Food ... to conduct regulated smart device and smart phone application ... research quality. "HITLAB is determined to improve ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a technology ... measures the overall facial feature of a person such ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... that is a primary target of the degenerative brain ... as Alzheimer's disease in patients who develop dementia before ... recently in evolutionary history -- in a common ancestor ... in humans, and the finding supports the concept that ...
... researchers at the University of Illinois at Urbana-Champaign have ... of social behavior in humans. , "The honey bee ... social behavior," said Saurabh (pronounced SAW-rub) Sinha, a professor ... Institute for Genomic Biology. Using that model system, Sinha ...
... general public alike have been acutely aware of the potential ... people might still recall the pandemics of 1968 and 1957, ... recurrence on that scale--that causes the most trepidation. ... people died from this particular strain of the flu virus ...
Cached Biology News:Study offers window into human behavior, brain disease 2Study offers window into human behavior, brain disease 3Study offers window into human behavior, brain disease 4Honey bee genome holds clues to social behavior 2Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million 2Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million 3
(Date:1/22/2015)... Madison, WI (PRWEB) January 22, 2015 Dr. ... at the 12th annual Scripps Natural Supplements Pre-Conference seminar on ... Supplements Conference is an annual continuing education conference for health ... 15th and included the topic of probiotics in health. Dr. ...
(Date:1/22/2015)... 22, 2015   Cypher Genomics, Inc., the ... SQNM ), the leading molecular diagnostics ... generation noninvasive prenatal tests (NIPT). Through this agreement, ... Mantis™, to advance analysis of clinically-relevant fetal sub-chromosomal ...
(Date:12/24/2014)... Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval application ... the use of Medtronic,s SynchroMed ® II implantable ... use with United Therapeutics, Remodulin ® (treprostinil) Injection ...
(Date:12/24/2014)... GMO corn cases filed across the United States, and ... being consolidated in a Kansas federal court for pretrial proceedings. ... Corn Litigation, MDL No. 2591 in the U.S. District Court ... GMO corn multidistrict litigation (MDL) has been handed over to ...
Breaking Biology Technology:Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2
... Abstract , ... that produce highpurity total RNA from biological sources such as cultured ... other manual handling, and produce a highly pure product, free of ... These new techniques respond to the demand ...
... Overview , ... biomarkers increases in importance, extensive lists of candidate markers are being ... larger numbers of candidate genomic markers exist from DNA transcriptional profiling ... While these genomic markers can ...
... Wild-type T4 Polynucleotide Kinase (PNK) ... 5'-ends of DNA and oligonucleotides. Labeling, in particular, can be ... reaction (Fig. 1) (3) . Historically, T4 PNK has played ... be important in applications such as labeling of probes for ...
Cached Biology Technology:Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 2Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 3Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 4Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 5Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 6Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 2Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 3Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 4Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 5 USB OptiKinase Eliminates Base Bias in Labeling of Oligonucleotide 5'-Ends 2 USB OptiKinase Eliminates Base Bias in Labeling of Oligonucleotide 5'-Ends 3
Request Info...
Automated -80° C sample library for microplates and cryotube racks in SBS format; for integration into automated processes....
Automated -80° C sample library for microplates and cryotube racks in SBS format; for integration into automated processes....
Automated centrifuge for the processing of microplates and tubes; can be integrated into automated process using inexpensive robotics due to its unique sample handling platform....
Biology Products: