Navigation Links
Reproductive tract secretions elicit ovulation
Date:4/17/2013

will. Mice with the same properties would be a much bigger challenge to produce and would yield results much more slowly. Of course, such studies could not be undertaken with humans.

Using these special tools, the researchers confirmed that one important role of reproductive tract secretions is to protect and store sperm. At least 25 secretory cells are required, and their products attract sperm to glands where they can remain safely while bathed in the secretory fluid. Similar storage takes place in a region of the human Fallopian tube known as the isthmus. Sperm are thought to persist in the isthmus for only a few days, but can be stored for a week or more in the case of fruit flies. When production of the secretion is compromised, sperm have difficulty getting to the gland and those that can make it undergo abnormal changes.

The secretory "machinery" studied in these experiments may allow the reproductive tract to signal the ovary when it is ready to receive an egg. Waiting for such a signal before releasing an egg could reduce the chance that an egg would fail to enter the reproductive tract or arrive before active sperm were available.

Interestingly, Spradling and Sun's work shows that different secretions are responsible for ovulation from those responsible for attracting and storing sperm. Identifying the specific secretory cell products (and the corresponding genes) that are required for successful ovulation would be an important step in understanding the mechanisms of this still-mysterious process.

This research has a possible connection to one of the most common forms of ovarian cancer, which was recently shown to derive from abnormalities in reproductive tract secretory cells. The genes and pathways that cells use in carrying out their normal functions are often the targets of the alternations that drive cancer cell growth. Thus, this work should stimulate investigation of the role played by genes such as Lrh1 in this deva
'/>"/>

Contact: Allan Spradling
spradling@ciwemb.edu
410-246-3015
Carnegie Institution
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Reproductive health providers should discuss environmental exposure risks with patients
2. Highly exposed to phthalates as fetuses, female mice have altered reproductive lives
3. BPA could affect reproductive capabilities, cause infection of the uterus
4. Rare cliffhanging plant species uses unique reproductive strategy
5. Report from the front lines of personalized reproductive medicine revolution
6. Sex of early birds suggests dinosaur reproductive style
7. Bisphenol A affects sex-specific reproductive behaviors in a monogamous animal species
8. Stanford scientist uncovers the reproductive workings of a harvester ant dynasty
9. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
10. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
11. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... , July 7, 2015  Based on ... Frost & Sullivan recognizes Credence ID, LLC with ... Entrepreneurial Company of the Year Award. Credence ID ... aid in its mission of offering enrollment and ... globally. As Credence ID was formed by experts ...
(Date:7/2/2015)... , July 2, 2015 Fingerprint Cards ... FPC1035, FPC1145 and FPC1155 from the distributor World Peace Industrial ... FPC,s distributors in Asia . Deliveries are ... sensors will be used by smartphone manufacturers in ... included in the communicated revenue guidance of approximately 2,200 MSEK ...
(Date:6/26/2015)... SPRINGVILLE, Utah , June 26, 2015 ATL ... assemblies and devices with specialties in single use solutions, headquartered ... acquisition of MedConx, Inc. (a California ... , and San Jose, Costa Rica ). ... Costa Rica with ATL Technology,s existing ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2
... compact microscope invented at Rice University is proving its ... published online today in the journal PLoS ONE ... his portable, battery-operated fluorescence microscope, which costs $240, stacks ... as $40,000 in diagnosing signs of tuberculosis. Miller ...
... University of Washington two years ago launched an ambitious project ... The game, Foldit, turns one of the hardest problems in ... Thousands of people have now played a game that asks ... or rescue a princess. Results published Thursday (Aug. 5) ...
... vast 1.5 million acres of mangrove swamps, sawgrass prairies ... of grass--be affected by the Gulf oil spill? ... entered the Loop Current or reached the Everglades, this ... study the effects of the spill on seagrasses and ...
Cached Biology News:Compact microscope a marvel 2Compact microscope a marvel 3Gaming for a cure: Computer gamers tackle protein folding 2Gaming for a cure: Computer gamers tackle protein folding 3Gaming for a cure: Computer gamers tackle protein folding 4Gulf oil spill: NSF funds research on impacts to Florida Everglades 2
(Date:7/30/2015)... ... July 30, 2015 , ... Leading regenerative veterinary medicine company, ... canine osteoarthritis stem cell product, currently under development for FDA approval. The product ... marketed in the US by Aratana. This product, termed AT-016, is an allogeneic ...
(Date:7/30/2015)... 30, 2015 Ascendis Pharma A/S (Nasdaq: ... its innovative TransCon technology to address significant unmet ... a six-month Phase 2 study to evaluate the ... in 53 treatment-naïve, pre-pubertal children with growth hormone ... pleased with the top-line results from our Phase ...
(Date:7/30/2015)... ... July 30, 2015 , ... GEA's Pony™ NS2006L ... operation up to 1500 bar. The sanitary design gauge of the NS2006L is ... , The Pony™ NS2006L homogenizer is an ideal solution for the processing of ...
(Date:7/29/2015)... US-Australian drug discovery company, Novogen Limited (ASX: ... committed to progressing its ground-breaking technology platforms to Phase ... ensure the Company delivers the best value for shareholders. ... , said the Company currently had an extensive program ... programs and academic partnerships and initiatives, and he was ...
Breaking Biology Technology:VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 2Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 4Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 6Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 7GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10
... Inc.,(OTC Bulletin Board: AVNA), announced today that its ... from SELEX GALILEO,totaling $629,000. SELEX GALILEO, a Finmeccanica ... organizations, is a leader in,surveillance, protection, tracking, targeting, ... the third order in 18 months from,SELEX GALILEO. ...
... CHAGRIN FALLS, Ohio, June 24 Knowledge Enterprises,Inc. ... the 4th Annual Orthopaedic Manufacturing & Technology Exposition ... 2007, with total attendance,nearing 1,000. "Based on the ... honored to report that OMTEC has secured a ...
... of Proven Clinical Trial Capability into the Frontage ... ... June 24 Frontage Laboratories,( http://www.frontagelab.com ) (Malvern and Exton, ... of bioanalytical, pre-clinical and,drug development services to the pharmaceutical industry, ...
Cached Biology Technology:Advance Nanotech's Owlstone Subsidiary Receives a $629,000 Order From Selex Galileo 2Advance Nanotech's Owlstone Subsidiary Receives a $629,000 Order From Selex Galileo 3Advance Nanotech's Owlstone Subsidiary Receives a $629,000 Order From Selex Galileo 4OMTEC 2008 Boasts Record Attendance and Secures Premier Position as Must-attend for Orthopaedic Companies 2Frontage Laboratories Completes Acquisition of Advanced Biomedical Research, Inc. (ABR) 2Frontage Laboratories Completes Acquisition of Advanced Biomedical Research, Inc. (ABR) 3Frontage Laboratories Completes Acquisition of Advanced Biomedical Research, Inc. (ABR) 4
Standard 2" or 3" Plastic can be ordered with 81 or 100 cell dividers. Mini 2" Plastics Boxes come standard with 25 cell dividers. Plastic boxes can also be ordered with corresponding freezer racks...
Ultra Pure Grade. Used in conjunction with IPTG to identify bacterial colonies that contain recombinant plasmids by blue/white selection. X-Gal forms an intense blue precipitate in the presence of be...
Request Info...
4-Hydroxy-3-nitrophenylacetyl hapten is conjugated to KLH (Keyhole Limpet Hemocyanin) lysine through amide bonds....
Biology Products: