Navigation Links
Reproductive biologists move in vitro fertilization knowledge forward
Date:10/28/2013

cal process. And when the ionophore is washed away, the sperm retain just the calcium they need. They self-regulate the optimal calcium concentration and are ready to go on."

He adds, "Our laboratory is mainly interested in the basic science of how sperm acquire fertilizing capacity, but one interesting idea here is that this shortcut offers some translational possibilities for calcium ionophore use in IVF. This shortcut may address many of the difficult situations we encounter in IVF, in many species."

In the JBC finalist for "Paper of the Week," Visconti and colleagues including Ana Maria Salicioni address a long-standing question about the presence or not of transmembrane adenylyl cyclases in the highly compartmentalized sperm head and tail and their functional pathways.

Salicioni says, "We show that the rules for producing cAMP in head and tail are different and the targets are different. The main target in the tail is PKA. In the head the target is not clear yet, but it certainly is not PKA. So the cAMP pathways in head and tail are completely different, which is entirely new."

Using biochemical analysis methods in knockout mice, Visconti and colleagues show that while the soluble adenylyl cyclase (sAC) is present in the tail, transmembrane adenylyl cyclases (tmAC) are present in the head sperm compartment. These enzymes are involved in the synthesis of cAMP and, unexpectedly, the signaling pathways using this second messenger are different in the head and tail.


'/>"/>

Contact: Janet Lathrop
jlathrop@admin.umass.edu
413-545-0444
University of Massachusetts at Amherst
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Sex over survival: Reproductive trait in fish impedes tissue regeneration
2. Reproductive BioMedicine Online publishes study on assisted reproduction
3. Reproductive tract secretions elicit ovulation
4. Stanford scientist uncovers the reproductive workings of a harvester ant dynasty
5. Bisphenol A affects sex-specific reproductive behaviors in a monogamous animal species
6. Sex of early birds suggests dinosaur reproductive style
7. Report from the front lines of personalized reproductive medicine revolution
8. Rare cliffhanging plant species uses unique reproductive strategy
9. BPA could affect reproductive capabilities, cause infection of the uterus
10. Highly exposed to phthalates as fetuses, female mice have altered reproductive lives
11. Reproductive health providers should discuss environmental exposure risks with patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Reproductive biologists move in vitro fertilization knowledge forward
(Date:3/20/2015)... Conn. , March 20, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... smart wallet is one of the products featured in ... March 20th at 11:00 PM EST on the DIY ... to Las Vegas , site of ...
(Date:3/18/2015)... March 18, 2015 As mobile payments ... revolutionary smart wallets and apps continue to be introduced into ... in the mobile payment industry in focus today are:  NXT-ID, ... (NYSE: BABA ), Apple Inc. (NASDAQ: ... Facebook Inc. (NASDAQ: FB ) NXT-ID, ...
(Date:3/17/2015)... NEW YORK , March 17, 2015 /PRNewswire/ ... , the largest exhibition for service robots ever ... . RoboUniverse takes place on May 11-13, 2015 ... Sponsors and exhibitors for the event include: Acorn ... Motion Control; EZ-Robot; Infranor; Kinova Robotics; Littler; NewBotic ...
Breaking Biology News(10 mins):NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2
... This press release is available in ... have found that unmanned aerial vehicles (UAVs), a tool used ... on changing land-use patterns across vast tracts of western rangeland. ... to survey vast, remote rangelands to see how they are ...
... sorghum hybrid that does not flower and accumulates as much ... may help the bioenergy industry, according to a study appearing ... Sciences. A team at Texas AgriLife Research has ... proceedings. "For energy crops, we want to prevent plants ...
... DigitalPersona, Inc. , a global provider of ... portfolio of fingerprint biometric Civil ID solutions ... Tampa, Fla. Supported by the National Institute of Standards ... the Biometric Consortium Conference is focused on biometric technologies ...
Cached Biology News:A labor saving way to monitor vast rangelands 2Gene controlling flowering boosts energy production from sorghum 2Gene controlling flowering boosts energy production from sorghum 3DigitalPersona Showcases Fingerprint Biometrics for Civil ID Applications at the Biometric Consortium Conference 2DigitalPersona Showcases Fingerprint Biometrics for Civil ID Applications at the Biometric Consortium Conference 3
(Date:4/16/2015)... 2015 /CNW/ - Bioenterprise Corporation is pleased to announce that ... Charlottetown , PEI.  Bioenterprise has established a ... Council for the commercialization of agricultural technologies and innovations. ... PEI ADAPT.  They have been at the heart of ... explains Dave Smardon , President & CEO of ...
(Date:4/16/2015)... DIEGO , April 16, 2015  AnaptysBio, ... development of therapeutic antibodies, today announced the ... antibody program into IND-enabling studies. The Company,s ... novel treatment for generalized pustular psoriasis (GPP), ... unmet medical need. ANB019 is wholly owned within ...
(Date:4/16/2015)... 2015  EMD Serono today announced the US ... Germany , appointed Alise Reicin , ... Clinical Development.  Dr. Reicin brings extensive research and ... and Immunology. She is an accomplished pharmaceutical executive ... Vice President in various capacities across R&D at ...
(Date:4/16/2015)... 16, 2015 Fairleigh Dickinson University ... Gulfo to become the Executive Director of the ... announced the kick-off of the Initiative for Patient ... Dr. Gulfo, under the Rothman Institute of Innovation ... and in collaboration with FDU’s School of Pharmacy’s ...
Breaking Biology Technology:Bioenterprise Corporation Expands into the Maritimes 2AnaptysBio Advances First-In-Class Anti-IL-36 Receptor Antibody Program To Treat Orphan Inflammatory Disease 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 3Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 2Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 3
... DIEGO, Nov. 6 Halozyme Therapeutics, Inc.,(Nasdaq: ... targeting the extracellular matrix for the drug delivery,endocrinology, ... the three and nine months ended September 30, ... been stronger and I am,pleased with the initiation ...
... 6 /PRNewswire-FirstCall/ - Dr. Brad Thompson, President,and CEO of ... a,corporate overview of the Company at the Rodman & ... at 11:10 a.m. ET. The,event will be held at ... A live audio webcast of the presentation will ...
... Highlights:, * Submitted NDA with FDA for NGX-4010 for management of pain ... ... EMEA,s scheduled Day 120 questions regarding MAA under ... SAN MATEO, Calif., Nov. 6 NeurogesX, Inc.,(Nasdaq: NGSX ), a biopharmaceutical ...
Cached Biology Technology:Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 2Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 3Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 4Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 5Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 6Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 7Halozyme Therapeutics Reports 2008 Third Quarter Financial Results 8Media Advisory - Oncolytics Biotech Inc. to Present at Rodman & Renshaw 10th Annual Healthcare Conference 2NeurogesX Reports Third Quarter 2008 Results 2NeurogesX Reports Third Quarter 2008 Results 3NeurogesX Reports Third Quarter 2008 Results 4NeurogesX Reports Third Quarter 2008 Results 5NeurogesX Reports Third Quarter 2008 Results 6NeurogesX Reports Third Quarter 2008 Results 7NeurogesX Reports Third Quarter 2008 Results 8NeurogesX Reports Third Quarter 2008 Results 9
Required to perform reference file generation, flatfield calibration and performance verification processes on the GSD-501...
Applications: Immunohistochemistry, ISH, FISH, CISH....
Applications: Immunohistochemistry, ISH, FISH, CISH....
Polypropylene test tube racks, used in Thermo Forma's line of Test Tube Rack holders...
Biology Products: