Both green chemistry and industrial biotechnology are important emerging trends worldwide. Enzymes are central to both disciplines so developments are likely to increase the focus on biocatalysis and encourage its wider implementation within industry.
There are many potential sources of innovative enzymes that could meet the needs of pharma. These include organisms from extreme environments and genomic databases. New and old enzymes can be optimized for their properties using technologies such as directed evolution.
Key reasons to purchase this research
- What benefits do enzymes offer compared with conventional chemical synthesis?
- How can an enzymatic steps be integrated into an existing manufacturing process and what are the challenges in so doing?
- Why are enzymes such a key focus in both green chemistry and industrial biotechnology?
- How can a natural enzyme be modified so that its properties are compatible with process conditions typically found in the pharmaceutical industry?
- What sectors of industry currently make the best use of enzymes in their processes and can pharma follow suit?
Table of Contents
About the author 2
Executive summary 11
Industrial biotechnology 11
Green chemistry in drug manufacturing 12
Enzymes and the enzyme industry 13
Overview of the use of enzymes in drug manufacturing 13
Case histories of biocatalysis 14
Industrial enzymes from extremophiles 15
The way forward 16
Enzyme companies and their products 17
Chapter 1 Introduction 18
Technical advantages of biocatalysis 21
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