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Reportlinker Adds Biomarkers - technologies, markets and companies
Date:9/7/2010

coproteomics for development of personalized medicine.

Many of the regulatory issues concerning biomarkers are related to genomics, proteomics, molecular diagnostics and pharmacogenomics/pharmacogenetics. Validation of biomarkers and their role in clinical trials is discussed.

Biomarker markets are estimated from 2009 to 2019 according to share of markets for various technologies and applications: proteomics, metabolomics, molecular diagnostics, drug discovery, clinical trials, and bioinformatics. Market values are further split according to therapeutic applications and major geographical areas. Unfulfilled needs in biomarkers are identified as well as the drivers for biomarker markets. Challenges facing the biomarker industry and strategies for developing biomarker markets are discussed.

A large number of companies with varying technical backgrounds are involved in biomarkers and 265 of these are profiled in part 2 of the report with classification into various categories.These also include major pharmaceutical companies. There is tabulation of 479 collaborations between companies and additional academic collaborations are mentioned in the individual profiles of companies. The report is supplemented by 800 references, 62 tables and 12 figures

TABLE OF CONTENTS

0. Executive Summary 19

1. Introduction 21

Definitions 21

Historical aspects of biomarkers 21

Classification of biomarkers 22

Biological marker as response to therapeutic intervention 23

Pharmacokinetic/pharmacodynamics biomarkers 23

Predictive biomarkers 23

Valid biomarkers 24

Types of biomarkers 24

Genes as biomarkers 24

Proteins as biomarkers 25

Proteomics 25

DNA biomarkers 26

Mitochondrial DNA 26

Mitochondrial mutations 26

RNA biomarkers 26

Transcriptomics 27

MicroRNAs 28

Metabolomics 28

Glycomics 28

Single nucleotide p
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