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Rensselaer researchers create accurate computer model of RNA tetraloop
Date:9/16/2013

ose four bases, but only three sequences actually appear in tetraloops. Once formed, they are highly stable, outlasting other structures when subjected to the destructive force of increasing heat.

"Tetraloops are sequences which are highly conserved throughout evolution; you find them everywhere, from bacteria to humans," said Garcia. "From one organism to another, many things can change, but when tetraloops change, they change from one sequence of four bases to one of the other three. They stack against each other and they are hyperstable. And there is a reason for them to be arranged the way they are."


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Contact: Mary Martialay
martim12@rpi.edu
518-276-2146
Rensselaer Polytechnic Institute
Source:Eurekalert

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