Navigation Links
Rensselaer researcher wins prestigious American Cancer Society award for work on cancer
Date:10/14/2010

ine milk ducts. In the early stages of the disease, the epithelial cells begin to grow abnormally, but are still confined within the lining of the milk ducts. At that point, the cancerous growth can still be excised with a surgeon's knife.

But with continued growth, the cancerous cells break through the barrier between the lining and the surrounding tissue the stroma at which point they come into contact with a different type of cell called fibroblasts. Now the cancer is progressing into the body. Unchecked, it will reach the bloodstream at which point it becomes far more difficult to treat.

"Normally fibroblasts live in stroma, epithelial cells live in ducts, and they never make physical contact. They don't come into contact with one another until there is pathological situation cancerous cells have broken the membrane, and invaded the stroma," Ligon said. "When that happens, they run into each other and we don't know much about the consequences of that contact between epithelial cells and fibroblasts."

In an earlier study, Ligon found that cancerous epithelial cells and fibroblasts do adhere to one another, despite expressing different cadherins.

"Everyone thought they wouldn't stick together, but when we introduced mildly invasive cancerous epithelial cells to normal fibroblasts, a certain percentage stick together," Ligon said.

"What we don't know is whether that will happen with normal epithelial cells or more invasive cancerous epithelial cells and fibroblasts," Ligon said. Those questions will form the basis for her next series of experiments, in which Ligon will introduce cancerous epithelial cells of varying invasiveness to healthy fibroblasts and observe the outcome.

Ligon said the results of her experiments could shed light on another puzzle: Whether her early results in which the cancerous epithelial cells and healthy fibroblasts did adhere bode ill or good for the patient.

"It is
'/>"/>

Contact: Mary Martialay
martim12@rpi.edu
518-276-2146
Rensselaer Polytechnic Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Rensselaer professors Dordick and Interrante named ACS Fellows
2. Purifying proteins: Rensselaer researchers use NMR to improve drug development
3. Rensselaer professor uncovers mysterious workings of cholera bacteria
4. Left or right? Early clues to soccer penalty kicks revealed at Rensselaer Polytechnic Institute
5. Rensselaer Polytechnic Institute professor Peter M. Tessier named Pew Scholar
6. Rensselaer Polytechnic Institute professor Patrick Underhill receives NSF CAREER award
7. Rensselaer Polytechnic Institute wins $2.45 million grant to support stem cell research
8. Rensselaer researchers to send bacteria into orbit aboard space shuttle Atlantis
9. Rensselaer leads effort to replace 1 of the most widely used drugs in American hospitals
10. Rensselaer receives more than $2 million from New York State to fund stem cell research
11. Trustee makes donation to start new solar energy research center at Rensselaer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... DUBLIN , Dec. 22, 2014 /PRNewswire/ ... ) has announced the addition of the ... report to their offering. ... This insight provides an overview of the ... Watermarking aims to control and monitor piracy ...
(Date:12/19/2014)... 2014   LaunchKey , the first decentralized mobile ... Internet of Things era, today announced the close of ... was led by Metamorphic Ventures with participation from ENIAC ... and others.  LaunchKey has raised $4 million to date, ... team and bring LaunchKey to market in 2015. ...
(Date:12/17/2014)... DUBLIN , Dec. 16, 2014 Research ... announced the addition of the "Global Chemical ... http://photos.prnewswire.com/prnh/20130307/600769 ... is the increasing demand for medical sensors in ... patient data for quick and correct diagnosis during ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... - Materials engineers have created a new type of ... might be used for environmental cleanup, water purification and ... than conventional filters for separating oil from water and ... are usually mutually exclusive. Researchers attached the material to ...
... campaign, Barack Obama proposed an economic plan that would ... "green collar" jobs do, in fact, present the next ... Duke University. , Highlighting the direct linkages between ... manufacturing is poised to grow in a low-carbon economy. ...
... Landing, California--Off the coast of Central California, in the ... metal pyramid about the size of two compact cars ... pyramid is the heart of the Monterey Accelerated Research ... continental United States. Six years and $13.5 million dollars ...
Cached Biology News:New filtering technology has environmental, industrial applications 2New filtering technology has environmental, industrial applications 3Duke study pinpoints potential 'green collar' job growth in US 2New deep-sea observatory goes live 2New deep-sea observatory goes live 3New deep-sea observatory goes live 4
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. ... on gynecologic disease, announced today that the Company ... including Oracle Investment Management, Jack W. Schuler ... Total proceeds were $10.5 million, before offering expenses.  ... and general corporate purposes. Under the ...
(Date:12/24/2014)... 2014 SoundConnect’s ... to introduce cutting edge communication technology, provide ... of platform upgrades. This webinar series demonstrates ... in their quest to leverage web conferencing’s ... to SoundConnect’s Marketing Manager, Seanna Baumgartner, “Our ...
(Date:12/24/2014)... The report expects global cell isolation and ... also provides a carefully analyzed data about the vital ... market. , Full Copy of Report @ http://bit.ly/1yUxy0T ... for cell expansion will keep witnessing growth at an ... to be driven by rapid technological advancements, government funding ...
(Date:12/24/2014)... Sigma-Aldrich Corporation (NASDAQ: SIAL ... the Hart-Scott-Rodino Antitrust Improvements Act (HSR Act) in ... 2014, thereby completing the U.S. HSR Act antitrust ... the Company by Merck KGaA, Darmstadt, Germany.  ... to closing the transaction, which remains subject to ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3
... full day with the announcement of the 2010 Kavli ... by Harold Varmus, co-chair of President Obama,s Council of ... live simulcast of the announcement of the laureates by ... Norway. A panel discussion follows, moderated by Elizabeth ...
... Abviva, Inc. (Pink Sheets: ABVV), a biomedical company engaged in ... today provided further details about worldwide patent protection for its breast ... , , ... Office issued two patents on the core technology that may be ...
... MILFORD, Mass. , May 21 Waters® Corporation ... Maryland announced today they have formed a groundbreaking partnership ... scientists from foreign governments and manufacturers on the state-of-the-art methods ... standards. Set to open next year, the International Food Safety ...
Cached Biology Technology:Abviva Details Patent Information for its Breast Cancer Risk Assessment Technology 2Abviva Details Patent Information for its Breast Cancer Risk Assessment Technology 3Groundbreaking International Training Lab to Strengthen Food Safety in U.S. and Globally 2Groundbreaking International Training Lab to Strengthen Food Safety in U.S. and Globally 3Groundbreaking International Training Lab to Strengthen Food Safety in U.S. and Globally 4
The LIC Duet™ Mini Adaptor encodes a T7 promoter, lac operator, ribosome binding site (rbs), and an ATG translation initation codon. This adaptor is designed for expression of a target protei...
... Cell Whole Genome Amplification Kit utilizes ... fragmentation of genomic DNA and conversion ... PCR-amplifiable library molecules flanked by universal ... PCR amplification of the library molecules ...
...
From formula-fed bovine calves Sterile, Cell culture tested...
Biology Products: