Navigation Links
Reliability of neuroscience research questioned
Date:4/10/2013

New research has questioned the reliability of neuroscience studies, saying that conclusions could be misleading due to small sample sizes.

A team led by academics from the University of Bristol reviewed 48 articles on neuroscience meta-analysis which were published in 2011 and concluded that most had an average power of around 20 per cent a finding which means the chance of the average study discovering the effect being investigated is only one in five.

The paper, being published in Nature Reviews Neuroscience today [10 April], reveals that small, low-powered studies are 'endemic' in neuroscience, producing unreliable research which is inefficient and wasteful.

It focuses on how low statistical power caused by low sample size of studies, small effects being investigated, or both can be misleading and produce more false scientific claims than high-powered studies.

It also illustrates how low power reduces a study's ability to detect any effects, and shows that when discoveries are claimed, they are more likely to be false or misleading.

The paper claims there is substantial evidence that a large proportion of research published in scientific literature may be unreliable as a consequence.

Another consequence is that the findings are overestimated because smaller studies consistently give more positive results than larger studies. This was found to be the case for studies using a diverse range of methods, including brain imaging, genetics and animal studies.

Kate Button, from the School of Social and Community Medicine, and Marcus Munaf, from the School of Experimental Psychology, led a team of researchers from Stanford University, the University of Virginia and the University of Oxford.

She said: "There's a lot of interest at the moment in improving the reliability of science. We looked at neuroscience literature and found that, on average, studies had only around a 20 per cent chance of detecting the effects they were i
'/>"/>

Contact: Philippa Walker
philippa.walker@bristol.ac.uk
44-117-928-7777
University of Bristol
Source:Eurekalert

Page: 1 2

Related biology news :

1. University of Minnesota invention helps advance reliability of alternative energy
2. The neuroscience of finding your lost keys
3. Scripps Florida scientist awarded prestigious Javits Neuroscience Investigator Award
4. RayBiotech, Inc. Executes Neuroscience Biomarker Master Services Agreement with Banner Sun Health Research Institute
5. Neuroscience: The extraordinary ease of ordinal series
6. Media registration opens for Neuroscience 2012, worlds largest brain science meeting
7. Wiring bats for neuroscience research
8. UCSF pair win Gruber Foundation Neuroscience prize
9. 6th Annual Canadian Neuroscience Meeting, Vancouver, May 20-23, 2012
10. Stanford and MIT scientists win Perl-UNC Neuroscience prize
11. Measuring microbes makes wetland health monitoring more affordable, says MU researcher
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... 20, 2015 Research and Markets ... the "India Sensors Market Forecast and Opportunities ... The sensor market is projected to grow at ... Consumer electronics, automotive, industrial and healthcare sectors are ... country. In addition, adoption of MEMS technology in ...
(Date:3/19/2015)... Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, announces its biometric payment technology, the Wocket® smart wallet ... on Washington DC,s Fox 5 News ... Next Great Thing", host Laura Evans calls the ... really big breakthrough in mobile payment.,  Award-winning ...
(Date:3/17/2015)...  MecklerMedia Corporation (OTCQX: MECK) announced its ... ever held in New York City ... 2015 at the Javits Convention Center. ... Acorn Product Development; Axis NJ; c-Link Systems; CoroWare; ... NewBotic Corporation; Neya Systems LLC; Reliabotics; RoboKind; RocketFarm ...
Breaking Biology News(10 mins):India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2
... herbs, especially Mexican oregano, all contain apigenin and luteolin, ... lab by inhibiting an important enzyme, according to two ... cell death in two aggressive human pancreatic cancer cell ... pre-treated cancer cells with apigenin for 24 hours, then ...
... In a study published on line this week in ... Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular ... Medical School, along with their colleagues, reported the unexpected ... inherited form of macular degeneration, turning off the animals, ...
... published papers, Tufts University School of Engineering researchers have ... cholera epidemics months before they occur and with a ... remote satellite imaging. Taken together, findings from these ... strengthen intervention efforts before the outbreak of cholera in ...
Cached Biology News:Celery, artichokes contain flavonoids that kill human pancreatic cancer cells 2Researchers report a critical role for the complement system in early macular degeneration 2Researchers report a critical role for the complement system in early macular degeneration 3Tufts scientists develop new early warning system for cholera epidemics 2Tufts scientists develop new early warning system for cholera epidemics 3
(Date:3/25/2015)... Diagnostics Inc. ("SQI" or the "Company") (TSX-V: SQD; OTCQX: ... with certain shareholders representing approximately 45% of the outstanding ... certain matters including the appointment of auditors at its ... 2015 (the "Meeting") it intends to adjourn the Meeting ... when the Meeting reconvenes. The Meeting will be reconvened ...
(Date:3/25/2015)... Vernon Hills, IL (PRWEB) March 25, 2015 ... new Cole-Parmer® Symmetry® Top-Loading Balances and Analytical Balances ... savvy. The expanded line of weighing balances from ... PT Precision Toploading Balances increase your efficiency ... of a variety of samples. Weighing modes include ...
(Date:3/25/2015)... , March 25, 2015  Point-of-Care Partners, ... management consulting firm, has launched the ePrescribing State ... simplify tracking of ePrescribing regulatory requirements in all ... ePrescribing regulatory landscape continues to change rapidly, so ... what the industry, and ultimately patients, need," said ...
(Date:3/25/2015)... HAGUE, Netherlands , March 25, 2015  EndoStim ... for chronic gastro-esophageal reflux disease (GERD) in the March ... Surgery . 2015; 157(3):556-567 ], establishing the long term ... The study included 25 patients with severe GERD ... prescribed daily proton pump inhibitor (PPI) medication for an ...
Breaking Biology Technology:SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5New Economical Top-Loading and Analytical Symmetry Balances from Cole-Parmer 2Point-of-Care Partners Launches the ePrescribing State Law Capsule 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 3
... Corporation,(OTC Bulletin Board: CONX), a worldwide developer and ... call on Thursday, September,25, 2008, at 4:00 PM ... for its fiscal year ended June 30, 2008, ... marketing activities., Corgenix invites all those interested ...
... ANNAPOLIS, Md., Sept. 15 PharmAthene, Inc.,(Amex: ... in the development and,commercialization of medical countermeasures ... it has received notification from,the Department of ... Company,s,proposal for its recombinant protective antigen anthrax ...
... Calif., Sept. 15 Advanced Chemical,Transport, one of ... the opening of a new location in Merced, ... environmental services -- hazardous,biological and radioactive waste disposal, ... environmental health and,safety outsourcing -- from the location ...
Cached Biology Technology:PharmAthene Response to DHHS Request for Proposals for Recombinant Protective Antigen Anthrax Vaccine Deemed Technically Acceptable and Within Competitive Range for Procurement Consideration 2PharmAthene Response to DHHS Request for Proposals for Recombinant Protective Antigen Anthrax Vaccine Deemed Technically Acceptable and Within Competitive Range for Procurement Consideration 3PharmAthene Response to DHHS Request for Proposals for Recombinant Protective Antigen Anthrax Vaccine Deemed Technically Acceptable and Within Competitive Range for Procurement Consideration 4Advanced Chemical Transport Opens Merced Facility 2
... is a G1 cyclin required for G1-phase ... a proto-oncogene. cyclin D2 can phosphorylate ... Species Reactivity: Human, Mouse, and Rat. ... is particularly well suited for neutralization of ...
Mouse Anti-Human Methyl-CpG binding domain protein 2 (MBD2 Monoclonal Antibody Family: Other Applications: Western Blot...
... Synthetic peptide corresponding to ... Antigen Family: Regulator ... Subfamily: not assigned-Regulator ... Storage: Long term: ...
V beta 5 Purified Anti-Human clone MH3-2, Isotype Mouse IgG 2a , kappa, 0.1 mg Consult technical datasheet for details....
Biology Products: