Navigation Links
Reducing gene-damaging impurities in medicines
Date:9/29/2010

Drug manufacturers have been adjusting to strict new government standards that limit the amount of potentially harmful impurities in medicine, according to the cover story of the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. The impurities are "genotoxic," capable of damaging the DNA in genes.

C&EN Senior Correspondent Ann Thayer notes that internationally accepted regulations long have limited the levels of impurities permitted in prescription drugs. But guidelines have not covered so-called genotoxic impurities (GTIs), substances that can potentially increase the risk of cancer. That changed in 2007, after European regulators put guidelines in place and the U.S. Food and Drug Administration soon after followed suit. The challenging new limits for GTIs are about 1,000 times lower than the levels allowed for most other impurities.

Although drug companies are complying with the guidelines, some regard the limits as too strict, the article notes. Some industry scientists also question the approaches proposed to categorize and test for GTIs. Nevertheless, drug companies are working to change or control their manufacturing methods so that GTIs either do not form in the first place or form at much lower levels.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Forest peoples rights key to reducing emissions from deforestation
2. Providing toilets, safe water is top route to reducing world poverty: UN University
3. Pollinator decline not reducing crop yields just yet
4. Reducing the damage of a heart attack
5. Effectiveness of progesterone in reducing preterm births may be altered by genetic predisposition
6. Biofuels can provide viable, sustainable solution to reducing petroleum dependence
7. Reducing CO2 through technology and smart growth
8. Reducing animal experiments through top-class research
9. Reducing the roadworks
10. The coming of biofuels: Study shows reducing gasoline emissions will benefit human health
11. Reducing risk of hospitalization in the elderly
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/9/2017)... MOUNTAIN VIEW, Calif. , March 9, 2017 /PRNewswire/ ... 23andMe , the leading personal genetics company, are ... can now provide customers with personalized nutrition plans that ... biometrics, but also genetic markers impacting how their body ... personalized food decision support platform uses biometrics such as ...
(Date:3/2/2017)... 2, 2017 Summary This report provides ... its partnering interests and activities since 2010. ... Read the full report: ... since 2010 report provides an in-depth insight into the partnering ... On demand company reports are prepared upon purchase ...
(Date:3/1/2017)... 2017  Aware, Inc. (NASDAQ: AWRE), a leading supplier ... P. Moberg has resigned, effective March 3, 2017, ... Officer and Treasurer of Aware citing a desire to ... member of the Board of Directors of Aware. ... Officer and co-President, General Counsel has been named Chief ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... Ca (PRWEB) , ... March 27, 2017 , ... ... colorectal cancer (mCRC) generally produce small, heterogeneous samples with limited tumor content in ... challenges remain to be resolved, such as the need for reliable detection of ...
(Date:3/27/2017)...  Perthera,s Chief Bioinformatics Officer and research faculty member ... Ph.D., will be speaking at the American Medical Informatics ... 27, 2017, she will be speaking on the topic ... and Care" (from 10:30 a.m. – 12:00 p.m. PST) ... a participant in the "Making Precision Oncology Data More ...
(Date:3/27/2017)... , ... March 27, 2017 , ... ... to engineer scalable and customizable vascular grafts in JoVE’s Video Journal, the world’s ... to new and improved ways of treating coronary artery disease (CAD). Lam is ...
(Date:3/27/2017)... , March 27, 2017 Neurotrope, Inc. ... therapies for neurodegenerative diseases, including Alzheimer,s disease, today ... application to list the Company,s common stock on ... The NASDAQ Stock Market, a unit of the ... will ring the Opening Bell at the NASDAQ ...
Breaking Biology Technology: