Navigation Links
Reducing gene-damaging impurities in medicines
Date:9/29/2010

Drug manufacturers have been adjusting to strict new government standards that limit the amount of potentially harmful impurities in medicine, according to the cover story of the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. The impurities are "genotoxic," capable of damaging the DNA in genes.

C&EN Senior Correspondent Ann Thayer notes that internationally accepted regulations long have limited the levels of impurities permitted in prescription drugs. But guidelines have not covered so-called genotoxic impurities (GTIs), substances that can potentially increase the risk of cancer. That changed in 2007, after European regulators put guidelines in place and the U.S. Food and Drug Administration soon after followed suit. The challenging new limits for GTIs are about 1,000 times lower than the levels allowed for most other impurities.

Although drug companies are complying with the guidelines, some regard the limits as too strict, the article notes. Some industry scientists also question the approaches proposed to categorize and test for GTIs. Nevertheless, drug companies are working to change or control their manufacturing methods so that GTIs either do not form in the first place or form at much lower levels.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Forest peoples rights key to reducing emissions from deforestation
2. Providing toilets, safe water is top route to reducing world poverty: UN University
3. Pollinator decline not reducing crop yields just yet
4. Reducing the damage of a heart attack
5. Effectiveness of progesterone in reducing preterm births may be altered by genetic predisposition
6. Biofuels can provide viable, sustainable solution to reducing petroleum dependence
7. Reducing CO2 through technology and smart growth
8. Reducing animal experiments through top-class research
9. Reducing the roadworks
10. The coming of biofuels: Study shows reducing gasoline emissions will benefit human health
11. Reducing risk of hospitalization in the elderly
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/18/2016)... LONDON , March 18, 2016 ... Established Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical ... & security companies in the border security market and ... and Europe has led ... your companies improved success. --> defence & ...
(Date:3/14/2016)... HANOVER , Allemagne, March 14, 2016 /PRNewswire/ ... http://www.apimages.com ) - --> - ... ) - --> ... les solutions biométriques, fournit de nouveaux lecteurs d,empreintes ... lecteur LF10 de DERMALOG sera utilisé pour produire ...
(Date:3/9/2016)... , March 9, 2016 This BCC Research ... states of the RNA Sequencing (RNA Seq) market for ... as instruments, tools and reagents, data analysis, and services. ... segments of the RNA-Sequencing market such as RNA-Sequencing tools ... the main factors affecting each segment and forecast their ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... NY (PRWEB) , ... May 26, 2016 , ... ... decades. FireflySci cuvettes are used in leading laboratories all over the globe. ... day. , In addition to manufacturing awesome cuvettes, FireflySci makes spectrophotometer calibration standards ...
(Date:5/25/2016)... ... 25, 2016 , ... The American Medical Informatics Association (AMIA) ... National Coordinator for Health IT (ONC) outlining a measurement approach to interoperability that ... when and where it was needed. The organization of health informatics professionals said ...
(Date:5/24/2016)... ... 24, 2016 , ... Cell therapies for a range of ... research at Worcester Polytechnic Institute (WPI) that yielded a newly patented method of ... The novel method, developed by WPI faculty members Raymond Page, PhD, professor of ...
(Date:5/23/2016)... ... May 23, 2016 , ... ... Precision Farming in 2017 and Beyond. The paper outlines the key trends that ... ag industry. , “We’ve witnessed a lot of highs and lows as the ...
Breaking Biology Technology: