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Red blood cell hormone modulates the immune system
Date:1/20/2011

at EPO may exert beneficial effects in non-infectious inflammatory diseases.

"Our results provide novel evidence that EPO acts as a potent anti-inflammatory immune modulator by specifically targeting (NF)-B-driven inflammatory pathways," concludes Manfred Nairz, first author of the paper. "Although high dose EPO treatment in humans may lead to a dangerous excess of red blood cells, EPO derivatives that do not influence red blood cell production have been developed and these could possibly serve as valuable therapeutic tools in treatment of pathologic inflammation."


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Contact: Elisabeth Lyons
elyons@cell.com
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Cell Press
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