Navigation Links
Red alert! How disease disables tomato plant's 'intruder alarm'
Date:12/4/2008

How a bacterium overcomes a tomato plant's defences and causes disease, by sneakily disabling the plant's intruder detection systems, is revealed in new research out today (4 December) in Current Biology.

The new study focuses on a pathogen which causes bacterial speck disease in tomato plants. This bacterial invasion causes black lesions on leaves and fruit. Severe infection can cause extensive and costly damage to tomato crops, and researchers believe that understanding more about how this microbe works could lead to new ways of tackling it, and other plant diseases, without the need for pesticides.

Scientists have found that the pathogen is very effective at attacking tomato plants because it deactivates and destroys receptors which normally alert the plant to the presence of a dangerous disease - in the same way that an intruder would deactivate the burglar alarm before gaining entry to a house.

Professor John Mansfield from Imperial College London's Department of Life Sciences, one of the authors of the paper, says: "Once the receptors have been taken out, the plant's defences are 'offline' and the bacterium is able to spread rapidly, feeding on the plant without encountering any kind of resistance."

Together with colleagues at the Max Planck Institute in Cologne and Zurich-Basel Plant Science Centre, Professor Mansfield used an experimental model plant called Arabidopsis, which is also affected by the disease, to examine what happens at the molecular level when bacterial speck infects a plant. The team found that the pathogen injects a protein into the host cell, which then deactivates and destroys, from the inside, receptors on the cell's surface which are designed to alert the plant to the presence of invading microbes.

Deactivating the receptors stalls the plant's defence mechanism in its initial stages - ordinarily the cell surface receptors would kickstart a chain reaction leading to the production of antimicrobial compounds to fight and kill off the bacterial invader.

Professor Mansfield says: "This area of research has a wider significance beyond black speck disease in tomato, because the microbes that cause plant diseases probably all employ similar attacking strategies to suppress resistance in their hosts. The more we understand about how the pathogens that cause disease overcome the innate immunity to infection in crop plants, the better our chances of developing approaches to disease control that do not require the use of potentially harmful pesticides"


'/>"/>

Contact: Danielle Reeves
danielle.reeves@imperial.ac.uk
44-020-759-42198
Imperial College London
Source:Eurekalert

Related biology news :

1. Antioxidant overload may underlie a heritable human disease
2. Gender, coupled with diabetes, affects vascular disease development
3. Study links cat disease to flame retardants in furniture and to pet food
4. Humans fostering forest-destroying disease
5. Emerging (disease) markets
6. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
7. Clemson chemists discover new way antioxidants fight debilitating diseases
8. Finding that 1-in-a-billion that could lead to disease
9. Study shows link between alcohol consumption and hiv disease progression
10. Natural chemical found in broccoli helps combat skin blistering disease
11. 60 second test could help early diagnosis of common brain diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
(Date:3/30/2017)... NEW YORK , March 30, 2017 ... by type (physiological and behavioral), by technology (fingerprint, AFIS, ... recognition, voice recognition, and others), by end use industry ... travel and immigration, financial and banking, and others), and ... Europe , Asia Pacific ...
(Date:3/28/2017)... India , March 28, 2017 ... IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software ... Vertical, and Region - Global Forecast to 2022", published ... Billion in 2016 and is projected to reach USD ... between 2017 and 2022. The base year considered for ...
Breaking Biology News(10 mins):
(Date:4/19/2017)... ... 19, 2017 , ... ThermaGenix, the PCR Improvement Company, announces ... several other early achievements at ThermaGenix, including the business formation and licensing agreements, ... will use proceeds from the Series A-1 round to:, , ...
(Date:4/19/2017)... ... April 19, 2017 , ... As part of the ... to novices as well as experienced users, attendees will gain a better understanding ... tests. , Hemostasis testing quality is determined by preanalytical variables which encompass ...
(Date:4/19/2017)... Calif. , April 19, 2017  As ... Drug Abuse and Heroin Summit ,  Proove┬« Biosciences, ... study analyzing genetics, environmental, and lifestyle factors to ... from the University of Southern California (USC), the ... , and Proove publish results showing that Proove ...
(Date:4/19/2017)... Calif. , April 19, 2017 ... ) today announced that it will report its ... market on Wednesday, May 3, 2017. Following the announcement, Veracyte,s management ... at 4:30 p.m. Eastern Time to discuss the company,s financial ... webcast and subsequent replay may be accessed by ...
Breaking Biology Technology: