Navigation Links
Recurrence of group B strep high in subsequent pregnancies, say UT Houston obstetricians

A new study by researchers at The University of Texas Medical School at Houston could help experts better decide whether to continue the current practice of retesting women during their second pregnancies for a common bacterial infection if they had tested positive for the infection previously.

Group B Streptococcus, or GBS, is a type of bacterial infection that is harmless to carriers but in some cases can be deadly to an infant passing through the mother's birth canal. It is normally found in the vagina and/or lower intestine of 10 to 30 percent of all adult women. GBS is not a sexually transmitted disease. Those women who test positive for GBS are considered "colonized."

Published in the Aug. 1, issue of Obstetrics and Gynecology, the two-year study included more than 5,000 women who delivered their babies between 2003 and 2004 in the greater Houston area.

"Of those women, we were able to follow 418 women who gave birth vaginally, had a second child or more, were tested for GBS during their first and second pregnancies, and were not excluded from the study due to various factors. We found that of the 418, the risk of testing positive for GBS during a second pregnancy was 53 percent," said lead author Mark A. Turrentine, M.D., clinical assistant professor of obstetrics and gynecology at the UT Medical School at Houston.

According to Turrentine, research is ongoing to determine why some women are colonized and others are not. There also will need to be further studies conducted on how to use the information from this study.

Current guidelines by the Centers for Disease Control and Prevention (CDC) and the American College of Obstetricians and Gynecologists (ACOG) state that since colonization varies from pregnancy to pregnancy, women should be screened with each pregnancy.

"Our study did not tackle this issue, but the results could help experts decide whether it is cost effective to keep testing women in subsequent pregnancies if their risk of testing positive remains so high," said Turrentine.

Although GBS is not harmful to the mother, it can be deadly to an infant passing through the mother's birth canal. Signs and symptoms usually happen within hours of birth. They can include: difficulty breathing; heart, blood pressure, kidney and gastrointestinal problems; and sepsis, pneumonia or meningitis.

Some of the symptoms that increase a woman's risk of passing GBS to her baby include: labor before 37 weeks, rupture of her amniotic membrane 18 hours or more before delivery, fever during labor, a urinary tract infection as a result of GBS during pregnancy and a previous baby with GBS disease.

The CDC recommends routine screening for GBS for all pregnant women. The screening is given between the 35th and 37th week of pregnancy.

"The test involves a swab of the vaginal-rectal area. If a woman tests positive, and is therefore considered colonized, she will most likely be treated with intravenous (IV) antibiotic therapy during labor. The antibiotics will help protect the infant," said co-author Mildred M. Ramirez, M.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at the UT Medical School at Houston.

According to the CDC, one of every 100 to 200 babies whose mothers carry GBS will, without antibiotics, develop signs and symptoms of GBS disease.

If a woman's GBS status is unknown at the time of delivery, the CDC, ACOG and American Academy of Pediatrics recommend the women be given IV antibiotics during labor. The recommended regimen is intravenous penicillin.


Contact: Melissa McDonald
University of Texas Health Science Center at Houston

Related biology news :

1. Urologists identify 7 biomarkers that may help pinpoint prostate cancer recurrence
2. High levels of estrogen associated with breast cancer recurrence
3. Western diet linked to increased risk of colon cancer recurrence
4. Len Hunt Joins Gallup Consulting Group
5. Researchers report the cloning of a key group of human genes, the protein kinases
6. Titanium Group to Attend Regional ICT Meeting in Thailand
7. Titanium Group Announces Contract for Security Solution in High-End Residentials
8. Nations and conservation groups seek plan to protect Ghost of the Himalayas
9. Group led by Stanford physicist says theres an urgent need for nuclear detectives
10. Madagascars tortoises are crawling toward extinction, groups say
11. Environmental groups call for increased protection of coral reefs
Post Your Comments:
(Date:11/10/2015)... Nov. 10, 2015  In this report, ... basis of product, type, application, disease indication, ... this report are consumables, services, software. The ... safety biomarkers, efficacy biomarkers, and validation biomarkers. ... are diagnostics development, drug discovery and development, ...
(Date:11/9/2015)... , Nov. 9, 2015  Synaptics Inc. (NASDAQ: ... today announced broader entry into the automotive market with ... match the pace of consumer electronics human interface innovation. ... are ideal for the automotive industry and will be ... Europe , Japan ...
(Date:10/29/2015)... Minn. , Oct. 29, 2015   MedNet ... supports the entire spectrum of clinical research, is pleased ... Minnesota High Tech Association (MHTA) as one of only ... in the "Software – Small and Growing" category. The Tekne ... individuals who have shown superior technology innovation and leadership. ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... new market research report "Oligonucleotide Synthesis Market by Product ... (PCR, Gene Synthesis, Diagnostic, DNA, RNAi), End-User (Research, Pharmaceutical ... published by MarketsandMarkets, the market is expected to reach ... in 2015, at a CAGR of 10.1% during the ...
(Date:11/24/2015)... SHPG ) announced today that Jeff Poulton , Chief ... Annual Healthcare Conference in New York City , ... p.m. GMT). --> SHPG ) announced today that ... Jaffray 27 th Annual Healthcare Conference in New ... 8:30 a.m. EST (1:30 p.m. GMT). --> Shire plc ...
(Date:11/24/2015)... CITY , Nov. 24, 2015 /PRNewswire/ - ... "Company") announced today that the remaining 11,000 post-share ... Share Purchase Warrants (the "Series B Warrants") subject ... were exercised on November 23, 2015, which will ... Shares.  After giving effect to the issuance of ...
(Date:11/24/2015)... ... November 24, 2015 , ... InSphero AG, the leading supplier of easy-to-use solutions ... Melanie Aregger to serve as Chief Operating Officer. , Having joined InSphero ... team and was promoted to Head of InSphero Diagnostics in 2014. There ...
Breaking Biology Technology: